Obstructive sleep apnea is independently associated with the metabolic syndrome in obese asian Indians in Northern India

Metabolic Syndrome and Related Disorders

Volumn 8, Issue 5, 2010, Pages 431-435

  Bhushan, Bharat ^a   Misra, Anoop ^b,c   Guleria, Randeep ^d  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Fortis Hospitals   (India)

^c National Diabetes Obesity and Cholesterol Foundation   (India)

^d ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ADULT; ARTICLE; BODY MASS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENDER; HUMAN; INDIAN; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; OBESITY; POLYSOMNOGRAPHY; PREVALENCE; PRIORITY JOURNAL; REGRESSION ANALYSIS; SLEEP APNEA SYNDROME;

ADULT; ANTHROPOMETRY; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; COMORBIDITY; FEMALE; HUMANS; INDIA; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY; POLYSOMNOGRAPHY; SLEEP APNEA, OBSTRUCTIVE;

EID: 77958145300     PISSN: 15404196     EISSN: None     Source Type: Journal    
DOI: 10.1089/met.2009.0125     Document Type: Article

References (24)

1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among mid¬dle-aged adults. N Engl J Med 1993;328:1230-1235.
2. Udwadia ZF, Doshi AV, Lonkar SG, Singh CI. Prevalence of sleep-disordered breathing and sleep apnea in middle-aged urban Indian men. Am J Respir Crit Care Med 2004;169: 168-173.
3. Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Nieto JF, O'Connor GT, Boland LI, Schwartz HE, Samet JM for the Sleep Heart Health Study Research Group. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 2001;163:19-25.
4. Misra A, Khurana L. Obesity and the metabolic syndrome in developing countries. J Clin Endocrinol Metab 2008;93(11 Suppl 1):S9-S30.
5. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syn¬drome. Lancet 2005;365:1415-1428.
6. Ahmed QA. Metabolic complications of obstructive sleep apnea syndrome. Am J Med Sci 2008;335:60-64.
7. Kiely JL, McNicholas WT. Cardiovascular risk factors in patients with obstructive sleep apnoea syndrome. Eur Respir J 2000;16:128-133.
8. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000;342:1378-1384.
9. Bhushan B, Guleria R, Misra A, Luthra K, Vikram N. K. TNF-alpha gene polymorphism and TNF-alpha levels in obese Asian Indians with obstructive sleep apnea. Respir Med 2008;103:386-392.
10. Vikram NK, Misra A, Pandey RM, Dwivedi M, Luthra K, Dhingra V, Talwar KK. Association between subclinical in¬flammation & fasting insulin in urban young adult north Indian males. Indian J Med Res 2006;124:677-682.
11. Dudeja V, Misra A, Pandey RM, Devina G, Kumar G, Vik-ram NK. BMI does not accurately predict overweight in Asian Indians in northern India. Br J Nutr 2001;86:105-112.
12. Bhushan B, Guleria R, Misra A, Pandey RM, Luthra K, Vikram NK. Obstructive Sleep Apnoea correlates with C-reactive protein in obese Asian Indians. Nutr Metab Cardio-vasc Dis 2009;19:184-189.
13. Rechtschaffen A, Kales A. A Manual of Standardized Ter¬minology, Techniques and Scoring System for Seep Stages of Human Subjects. Washington, DC: National Institutes of Health; 1968.
14. Sleep related breathing disorders in adults; recommenda¬tions for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22:667-689.
15. Misra A, Chowbey P, Makkar BM, Vikram NK, Wasir JS, Chadha D, Joshi SR, Sadikot S, Gupta R, Gulati S, Munjal YP. Consensus statement for diagnosis of obesity, abdomi¬nal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management. J Assoc Physicians India 2009:163-170
16. ASDA Diagnostic Classification Steering Committee. The International Classification of Sleep Disorders. Diagnostic and Coding Manual, 2nd ed. ASDA; 1997.
17. Ip MS, Lam B, Ng MM, Lam WK, Tsang KW, Lam KS. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med 2002;165:670-676.
18. Vikram NK, Misra A, Pandey RM, Luthra K, Bhatt SP. Distribution and cutoff points of fasting insulin in Asian Indian adolescents and their association with metabolic syndrome. J Assoc Physicians India 2008;56:949-954.
19. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SS Jr, Spertus JA, Costa F. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific State¬ment. Circulation 2005;112:2735-2752.
20. Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, D'Agostino AB, Lebowitz MD, Pickering TG. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA 2000;283:1829-1836.
21. Tassone F, Lanfranco F, Gianotti L, Pivetti S, Navone F, Rossetto R, Grottoli S, Gai V, Ghigo E, Maccario M. Ob¬structive sleep apnoea syndrome impairs insulin sensitivity independently of anthropometric variables. Clin Endocrinol (Oxf) 2003;59:374-379.
22. Coughlin SR, Mawdsley L, Mugarza JA, Calverley PM, Wilding JP. Obstructive sleep apnoea is independently as¬sociated with an increased prevalence of metabolic syn¬drome. Eur Heart J 2004;25:735-741.
23. Brooks B, Cistulli PA, Borkman M, Ross G, McGhee S, Grunstein RR, Sullivan CE, Yue DK. Obstructive sleep apnea in obese noninsulin-dependent diabetic patients: effect of continuous positive airway pressure treatment on insulin responsiveness. J Clin Endocrinol Metab 1994;79: 1681-1685.
24. Davies RJ, Turner R, Crosby J, Stradling JR. Plasma insulin and lipid levels in untreated obstructive sleep apnoea and snoring; their comparison with matched controls and re¬sponse to treatment. J Sleep Res 1994;3:180-185.