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1:CAS:528:DC%2BC3cXhsVSjsb4%3D 20333343 This is a good complementary review of gene transfer for therapy for erectile dysfunction
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A Melman KP Davies 2009 Gene therapy in the management of erectile dysfunction (ED): past, present, and future Scientific World Journal 9 846 854 1:CAS:528:DC%2BC3cXhsVSjsb4%3D 20333343 This is a good complementary review of gene transfer for therapy for erectile dysfunction
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Dec 25 (Epub ahead of print). This report demonstrates the versatility of plasmid-based therapy. In this case, the hSlo gene was used in a plasmid backbone with a smooth muscle-activated-only promoter. In addition, it demonstrated that the product could correct erectile dysfunction that was caused by atherosclerosis in a primate model
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•• Christ GJ, Andersson KE, Williams K, et al.: Smooth-Muscle-Specific Gene Transfer with the Human Maxi-K Channel Improves Erectile Function and Enhances Sexual Behavior in Atherosclerotic Cynomolgus Monkeys. Eur Urol 2008 Dec 25 (Epub ahead of print). This report demonstrates the versatility of plasmid-based therapy. In this case, the hSlo gene was used in a plasmid backbone with a smooth muscle-activated-only promoter. In addition, it demonstrated that the product could correct erectile dysfunction that was caused by atherosclerosis in a primate model.
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