Effects of CCK-8 and its receptor antagonists on μ-opioid receptor in prefrontal cortex, cauduate putamen and hippocampus of morphine withdrawal rats

Chinese Pharmacological Bulletin

Volumn 26, Issue 7, 2010, Pages 867-871

  Wen, Di ^a   Ma, Chun Ling ^a   Cong, Bin ^a   Zhang, Ya Jing ^a   Yang, Sheng Chang ^a   Yu, Feng ^a   Ni, Zhi Yu ^a   Li, Shu Jin ^a  

^a NONE

Author keywords

CCK receptor antagonists; CCK 8; Forensic toxicology; Morphine withdrawal; Radioligand binding assay; opioid receptor

Indexed keywords

CHOLECYSTOKININ OCTAPEPTIDE; DEVAZEPIDE; MORPHINE; MU OPIATE RECEPTOR; N (4 BROMOPHENYL) 3 OXO 4,5 DIPHENYL 1 PYRAZOLIDINECARBOXAMIDE; NALOXONE; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING ASSAY; DRUG DEPENDENCE; DRUG RECEPTOR BINDING; HIPPOCAMPUS; MORPHINE WITHDRAWAL SYNDROME; NONHUMAN; PREFRONTAL CORTEX; PUTAMEN; RAT; RECEPTOR UPREGULATION; WITHDRAWAL SYNDROME;

EID: 77958074934     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Faris P L, Komisaruk B R, Watkins L R, et al. Evidence for the neuropeptide cholecystokinin as an antagonist of opiate analgesia [J]. Science, 1983,219(4582):310-2.
2. Hebb A L, Poulin J F, Roach S P, et al. Cholecystokinin and endogenous opioid peptides: Interactive influence on pain, cognition and emotion [J]. Prog Neuropsychopharmacol Biol, Psychiatry, 2005,29(8):1225-38.
3. Gu J P, Cong B, Zhu G Y, et al. Effects of melatonin on cAMP and cGMP contents in some brain regions of morphine withdrawal rats [J]. Chin J Drug Depend, 2005,14(1):24-6.
4. Geliert V F, Holtzman S G. Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions [J]. J Pharmacol Exp Ther, 1978,205(3):536-46.
5. Tortorici V, Nogueira L, Salas R, et al. Involvement of local cholecystokinin in the tolerance induced by morphine microinjections into the periaqueductal gray of rats [J]. Pain, 2003,102(1-2):9-16.
6. Lu L, Huang M S, Liu Z Y, et al. CCK2 receptor antagonist attenuate morphine dependence and withdrawal in rats [J]. Neroreport, 2000,11(4):829-32. (Pubitemid 30173932)
7. Mitchell J M, Bergren L J, Chen K S, Fields H L. Cholecystokinin is necessary for the expression of morphine conditioned place preference [J]. Pharmacol Biochem Behav, 2006,85(4):787-95.
8. Rezayat M, Azizi N, Zarrindast M R. On the mechanism(s) of cholecystokinin(CCK): Receptor stimulation attenuates morphine dependence in mice [J]. Pharmacol Toxicol, 1997,81(3):124-9. (Pubitemid 27401988)
9. Yang C X, Yang B F, Zhang H, et al. Effects of CCK-8 on the withdrawal symptoms and expression of c-jun protein in Cd of morphinomania rats [J]. Chin Pharmacol Bull, 2008,24(9):1166-70.
10. Itoh S, Katsuura G, Maeda Y. Caerulein and cholecystokinin suppress beta-endorphin-induced analgesia in the rat [J]. Eur J Pharmacol, 1982,80(4):421-5. (Pubitemid 12032174)
11. Doi T, Juma I. Analgesic effect of intrathecal morphine demonstrated in ascending nociceptive activity in the rat spinal cord an in effectiveness of caerulein and CCK-8 [J]. Brain Res, 1982,234(2):399-407. (Pubitemid 12175905)
12. Zhou Y, Bendor J, Hofmann L, et al. Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal [J]. J Endocrinol, 2006,191(1):137-45. (Pubitemid 44756516)
13. i, CaM activity and CaMK II α expression in hippocampal neurons during naloxone-precipitated withdrawal in morphine-dependent rats [J]. Chin J Anesthesiol, 2009,29(11):1008-12.
14. Zhao L, Cong B, Wu Y Y, et al. Effect of expression of cholecystokinin receptor mRNA in primary culturing hippocampus neurons of newborn rat induced by morphine [J]. Chin Pharmacol Bull, 2006,22(4):479-83.
15. Yan Y X, Hu W L, Cong B, et al. Expressions of μ opioid receptor and CCK receptor in rat primary hippocampal neurons and effect of chronic morphine exposure on them [J]. J Fourth MilMed Univ, 2007,28(13):1214-7.