Kojyl thioether derivatives having both tyrosinase inhibitory and anti-inflammatory properties

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6569-6571

  Rho, Ho Sik ^a   Ahn, Soo Mi ^a   Yoo, Dae Sung ^c   Kim, Myung Kyoo ^b   Cho, Dong Ha ^c   Cho, Jae Youl ^c  

^a AmorePacific Corporation   (South Korea)

^b Samkyung Costech Co Ltd   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Anti inflammatory property; Derivatives; Kojyl thioether; Tyrosinase

Indexed keywords

2 (CYCLOHEXYLTHIOMETHYL) 5 HYDROXY 4H PYRAN 4 ONE; 2 (HEXYLTHIOMETHYL) 5 HYDROXY 4H PYRAN 4 ONE; 2 (PENTYLTHIOMETHYL) 5 HYDROXY 4H PYRAN 4 ONE; ALKYL GROUP; CYCLOHEXANE; ETHER DERIVATIVE; HEXANE; JV2 326; JV2 346; JV2 695; JV2 697; JV4 345; JV5 40; JV5 42; KOJIC ACID; MONOPHENOL MONOOXYGENASE; NITRIC OXIDE; PENTANE; SULFIDE; SULFONE; SULFONE DERIVATIVE; SULFOXIDE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASSAY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; LIPOPHILICITY; SYNTHESIS;

ANTI-INFLAMMATORY AGENTS; MODELS, MOLECULAR; MONOPHENOL MONOOXYGENASE; SULFIDES;

EID: 77958049068     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.042     Document Type: Article

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18. 570) was measured using a Spectramax 250 microplate reader (Molecular Devices, Sunnyvale, CA, USA). A standard curve of NO was made with sodium nitrite.
19. 570-630) was measured by a Spectramax 250 microplate reader.