Insulin resistance, a link between maternal overweight and fetal macrosomia in nondiabetic pregnancies

Hormone Research in Paediatrics

Volumn 74, Issue 4, 2010, Pages 267-274

  Ahlsson, Fredrik ^a,b   Diderholm, Barbro ^a   Jonsson, Björn ^a   Nordén Lindberg, Solvig ^a   Olsson, Roger ^a   Ewald, Uwe ^a   Forslund, Anders ^a   Stridsberg, Mats ^a   Gustafsson, Jan ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY CHILDREN S HOSPITAL   (Sweden)

Author keywords

Insulin resistance; Large for gestational age infants; Lipolysis

Indexed keywords

GLYCEROL;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; ENERGY EXPENDITURE; FEMALE; FETUS; FETUS GROWTH; FETUS WEIGHT; GLUCONEOGENESIS; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; LIPOLYSIS; MACROSOMIA; OBESITY; PREGNANCY; PRIORITY JOURNAL; RESTING SPORE;

ADIPOSITY; ADULT; BASAL METABOLISM; BODY COMPOSITION; BODY MASS INDEX; FEMALE; FETAL MACROSOMIA; FETAL WEIGHT; GLUCONEOGENESIS; HUMANS; INFANT, NEWBORN; INSULIN RESISTANCE; LIPOLYSIS; OVERWEIGHT; PREGNANCY; PREGNANCY TRIMESTER, THIRD; ULTRASONOGRAPHY, PRENATAL;

EID: 77958044177     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000295710     Document Type: Article

References (46)

1. Arbuckle TE, Sherman GJ: An analysis of birth weight by gestational age in Canada. CMAJ 1989; 140: 157-160, 165.
2. Alberman E: Are our babies becoming bigger? J R Soc Med 1991; 84: 257-260.
3. Power C: National trends in birth weight: implications for future adult disease. BMJ 1994; 308: 1270-1271.
4. Oja H, Koiranen M, Rantakallio P: Fitting mixture models to birth weight data: a case study. Biometrics 1991; 47: 883-897.
5. Singhal PK, Paul VK, Deorari AK, Singh M, Sundaram KR: Changing trends in intrauterine growth curves. Indian Pediatr 1991; 28: 281-283.
6. Surkan PJ, Hsieh CC, Johansson AL, Dickman PW, Cnattingius S: Reasons for increasing trends in large for gestational age births. Obstet Gynecol 2004; 104: 720-726.
7. Eriksson J, Forsen T, Tuomilehto J, Osmond C, Barker D: Size at birth, childhood growth and obesity in adult life. Int J Obes Relat Metab Disord 2001; 25: 735-740.
8. Eriksson M, Tibblin G, Cnattingius S: Low birthweight and ischaemic heart disease. Lancet 1994; 343: 731.
9. Welin L, Tibblin G, Svardsudd K, Tibblin B, Ander-Peciva S, Larsson B, Wilhelmsen L: Prospective study of social influences on mortality. The study of men born in 1913 and 1923. Lancet 1985; 1: 915-918. (Pubitemid 15009191)
10. Ekbom A, Hsieh CC, Lipworth L, Wolk A, Ponten J, Adami HO, Trichopoulos D: Perinatal characteristics in relation to incidence of and mortality from prostate cancer. BMJ 1996; 313: 337-341.
11. Innes K, Byers T, Schymura M: Birth characteristics and subsequent risk for breast cancer in very young women. Am J Epidemiol 2000; 152: 1121-1128.
12. Dahlquist G, Bennich SS, Kallen B: Intrauterine growth pattern and risk of childhood onset insulin dependent (type I) diabetes: population based case-control study. BMJ 1996; 313: 1174-1177.
13. Wei JN, Sung FC, Li CY, Chang CH, Lin RS, Lin CC, Chiang CC, Chuang LM: Low birth weight and high birth weight infants are both at an increased risk to have type 2 diabetes among schoolchildren in Taiwan. Diabetes Care 2003; 26: 343-348.
14. Ryan EA, Enns L: Role of gestational hormones in the induction of insulin resistance. J Clin Endocrinol Metab 1988; 67: 341-347.
15. Catalano PM, Tyzbir ED, Roman NM, Amini SB, Sims EA: Longitudinal changes in insulin release and insulin resistance in nonobese pregnant women. Am J Obstet Gynecol 1991; 165: 1667-1672.
16. Catalano PM, Tyzbir ED, Wolfe RR, Calles J, Roman NM, Amini SB, Sims EA: Carbohydrate metabolism during pregnancy in control subjects and women with gestational diabetes. Am J Physiol 1993; 264:E60-E67.
17. Ciaraldi TP, Kettel M, el-Roeiy A, Madar Z, Reichart D, Yen SS, Olefsky JM: Mechanisms of cellular insulin resistance in human pregnancy. Am J Obstet Gynecol 1994; 170: 635-641.
18. Stanley K, Fraser R, Bruce C: Physiological changes in insulin resistance in human pregnancy: longitudinal study with the hyperinsulinaemic euglycaemic clamp technique. Br J Obstet Gynaecol 1998; 105: 756-759.
19. Metzger BE, Unger RH, Freinkel N: Carbohydrate metabolism in pregnancy. XIV. Relationships between circulating glucagon, insulin, glucose and amino acids in response to a 'mixed meal' in late pregnancy. Metabolism 1977; 26: 151-156.
20. Sivan E, Homko CJ, Chen X, Reece EA, Boden G: Effect of insulin on fat metabolism during and after normal pregnancy. Diabetes 1999; 48: 834-838.
21. Kalhan S, Rossi K, Gruca L, Burkett E, O'Brien A: Glucose turnover and gluconeogenesis in human pregnancy. J Clin Invest 1997; 100: 1775-1781.
22. Diderholm B, Stridsberg M, Ewald U, Lindeberg- Norden S, Gustafsson J: Increased lipolysis in non-obese pregnant women studied in the third trimester. BJOG 2005; 112: 713-718.
23. Diderholm B, Stridsberg M, Norden-Lindeberg S, Gustafsson J: Decreased maternal lipolysis in intrauterine growth restriction in the third trimester. BJOG 2006; 113: 159-164.
24. Catalano PM, Drago NM, Amini SB: Maternal carbohydrate metabolism and its relationship to fetal growth and body composition. Am J Obstet Gynecol 1995; 172: 1464-1470.
25. Ferrannini E: The theoretical bases of indirect calorimetry: a review. Metabolism 1988; 37: 287-301.
26. Frayn KN: Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983; 55: 628-634.
27. Lukaski HC, Siders WA, Nielsen EJ, Hall CB: Total body water in pregnancy: assessment by using bioelectrical impedance. Am J Clin Nutr 1994; 59: 578-585.
28. Lof M, Olausson H, Bostrom K, Janerot-Sjoberg B, Sohlstrom A, Forsum E: Changes in basal metabolic rate during pregnancy in relation to changes in body weight and composition, cardiac output, insulin-like growth factor I, and thyroid hormones and in relation to fetal growth. Am J Clin Nutr 2005; 81: 678-685.
29. Rohl J, Huston-Presley L, Amini S, Stepanchak B, Catalano P: Factors associated with fetal growth and body composition as measured by ultrasound. Am J Obstet Gynecol 2001; 185: 1416-1420.
30. Ahlsson F, Gustafsson J, Tuvemo T, Lundgren M: Females born large for gestational age have a doubled risk of giving birth to large for gestational age infants. Acta Paediatr 2007; 96: 358-362.
31. Guideline on Validation of Limulus Amebocyte Lysate Test as an End-Product Endotoxin Test for Human and Animal Parenteral Drugs, Biological Products and Medical Devices. Washington, Food and Drug Administration, 1987.
32. Sjodin AM, Forslund AH, Westerterp KR, Andersson AB, Forslund JM, Hambraeus LM: The influence of physical activity on BMR. Med Sci Sports Exerc 1996; 28: 85-91.
33. Weir JB: New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949; 109: 1-9.
34. Forslund AH, Johansson AG, Sjodin A, Bryding G, Ljunghall S, Hambraeus L: Evaluation of modified multicompartment models to calculate body composition in healthy males. Am J Clin Nutr 1996; 63: 856-862.
35. Persson PH, Weldner BM: Intra-uterine weight curves obtained by ultrasound. Acta Obstet Gynecol Scand 1986; 65: 169-173.
36. Ahlsson FS, Diderholm B, Ewald U, Gustafsson J: Lipolysis and insulin sensitivity at birth in infants who are large for gestational age. Pediatrics 2007; 120: 958-965.
37. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
38. Niklasson A, Ericson A, Fryer JG, Karlberg J, Lawrence C, Karlberg P: An update of the Swedish reference standards for weight, length and head circumference at birth for given gestational age (1977-1981). Acta Paediatr Scand 1991; 80: 756-762.
39. Sivan E, Homko CJ, Whittaker PG, Reece EA, Chen X, Boden G: Free fatty acids and insulin resistance during pregnancy. J Clin Endocrinol Metab 1998; 83: 2338-2342.
40. Durnin JV, McKillop FM, Grant S, Fitzgerald G: Energy requirements of pregnancy in Scotland. Lancet 1987; 2: 897-900.
41. Kopp-Hoolihan LE, van Loan MD, Wong WW, King JC: Longitudinal assessment of energy balance in well-nourished, pregnant women. Am J Clin Nutr 1999; 69: 697-704.
42. Forsum E, Kabir N, Sadurskis A, Westerterp K: Total energy expenditure of healthy Swedish women during pregnancy and lactation. Am J Clin Nutr 1992; 56: 334-342.
43. Forsum E, Sadurskis A, Wager J: Resting metabolic rate and body composition of healthy Swedish women during pregnancy. Am J Clin Nutr 1988; 47: 942-947.
44. Bronstein MN, Mak RP, King JC: Unexpected relationship between fat mass and basal metabolic rate in pregnant women. Br J Nutr 1996; 75: 659-668.
45. Horowitz JF, Coppack SW, Paramore D, Cryer PE, Zhao G, Klein S: Effect of short-term fasting on lipid kinetics in lean and obese women. Am J Physiol 1999; 276:E278-E284.
46. Hills FA, English J, Chard T: Circulating levels of IGF-I and IGF-binding protein-1 throughout pregnancy: relation to birthweight and maternal weight. J Endocrinol 1996; 148: 303-309.