Seizures in extremely low birth weight infants are associated with adverse outcome

Journal of Pediatrics

Volumn 157, Issue 5, 2010, Pages

  Davis, Alexis S ^a   Hintz, Susan R ^a   Van Meurs, Krisa P ^a   Li, Lei ^b   Das, Abhik ^b   Stoll, Barbara J ^c   Walsh, Michele C ^d   Pappas, Athina ^e   Bell, Edward F ^f   Laptook, Abbot R ^g   Higgins, Rosemary D ^h  

^a STANFORD UNIVERSITY   (United States)

^b RTI INTERNATIONAL   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF IOWA   (United States)

^g BROWN UNIVERSITY   (United States)

^h EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

aEEG; Amplitude integrated EEG; ANS; Antenatal steroids; Birth weight; BPD; Bronchopulmonary dysplasia; BW; Cardiopulmonary resuscitation; Central nervous system; Cerebral palsy; CNS; CP; CPR; Early onset sepsis; EEG; ELBW; Electroencephalography; EOS; Extremely low birth weight; GA; Gestational age; Intraventricular hemorrhage; IVH; Late onset sepsis; LOS; Magnetic resonance imaging; MDI; Mental Development Index; MRI; National Institute of Child Health and Human Development; NDI; NEC; Necrotizing enterocolitis; Neonatal Research Network; Neurodevelopmental impairment; NICHD; NRN; Odds ratio; OR; Patent ductus arteriosus; PDA; PDI; Periventricular leukomalacia; PHH; PMA; Post hemorrhagic hydrocephalus; Postmenstrual age; Psychomotor Development Index; PVL; SGA; Small for gestational age; Ultrasound scanning; US

Indexed keywords

ARTICLE; BRAIN HEMORRHAGE; CEREBRAL PALSY; CONFOUNDING VARIABLE; DEMOGRAPHY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENCEPHALOMALACIA; EXTREMELY LOW BIRTH WEIGHT; FEMALE; HUMAN; INDEPENDENT VARIABLE; INFANT; INFANT MORTALITY; MAJOR CLINICAL STUDY; MALE; MENINGITIS; NEUROLOGIC DISEASE; NEWBORN; NEWBORN MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEIZURE; SEPSIS; SURVIVOR; COMPLICATION; DEVELOPMENTAL DISABILITIES; NERVOUS SYSTEM DISEASES; PROGNOSIS; SEIZURES; TIME;

DEVELOPMENTAL DISABILITIES; HUMANS; INFANT, EXTREMELY LOW BIRTH WEIGHT; INFANT, NEWBORN; NERVOUS SYSTEM DISEASES; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SEIZURES; TIME FACTORS;

EID: 77958033380     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2010.04.065     Document Type: Article

References (34)

1. M.J. Lanska, and D.J. Lanska Neonatal seizures in the United States: results of the National Hospital Discharge Survey Neuroepidemiology 15 1996 117 125
2. G.M. Ronen, S. Penney, and W. Andrews The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study J Pediatr 134 1999 71 75
3. K. Holden, E. Mellits, and J. Freeman Neonatal seizures I. Correlation of prenatal and perinatal events with outcomes Pediatrics 70 1982 165 176
4. M. Toet, F. Groenendaal, D. Osredkar, A. van Huffelen, and L. de Vries Postneonatal epilepsy following amplitude-integrated EEG-detected neonatal seizures Pediatr Neurol 32 2005 241 247
5. J. Walstab, R. Bell, D. Reddihough, S. Brennecke, C. Bessell, and N. Beischer Factors identified during the neonatal period associated with risk of cerebral palsy Austr N Z J Obstet Gynaecol 44 2004 342 346
6. M. McBride, N. Laroia, and R. Guillet Electrographic seizures in neonates correlate with poor neurodevelopmental outcome Neurology 55 2000 506 513
7. J. Perlman, and J. Volpe Seizures in the preterm infant: effects on cerebral blood flow velocity, intracranial pressure, and arterial blood pressure J Pediatr 102 1983 288 293 (Pubitemid 13194720)
8. M. Zupanc Neonatal seizures Pediatr Clin N Am 51 2004 961 978
9. L.G. van Rooij, M.C. Toet, A.C. van Huffelen, F. Groenendaal, W. Laan, and A. Zecic Effect of treatment of subclinical neonatal seizures detected with aEEG: randomized, controlled trial Pediatrics 125 2010 e358 e366
10. E. Mizrahi, and R. Clancy Neonatal seizures: early-onset seizure syndromes and their consequences for development Ment Retard Dev Disabil Res Rev 6 2000 229 241
11. E. Mellits, K. Holden, and J. Freeman Neonatal seizures II. A multivariate analysis of factors associated with outcome Pediatrics 70 1982 177 185
12. M.L. Nunes, M.P. Martins, B.M. Barea, R.C. Wainberg, and J.C. da Costa Neurological outcome of newborns with neonatal seizures Arq Neuropsiquiatr 66 2008 168 174
13. R. Guillet, and J. Kwon Seizure recurrence and developmental disabilities after neonatal seizures: outcomes are unrelated to use of phenobarbital prophylaxis J Child Neurol 22 2007 389 395
14. E. Broitman, N. Ambalavanan, R. Higgins, B. Vohr, A. Das, and B. Bhaskar Clinical data predict neurodevelopmental outcome better than head ultrasound in extremely low birth weight infants J Pediatr 151 2007 500 505
15. A.P. Neubauer, W. Voss, and E. Kattner Outcome of extremely low birth weight survivors at school age: the influence of perinatal parameters on neurodevelopment Eur J Pediatr 167 2008 87 95
16. F. Pisani, A. Barilli, L. Sisti, G. Bevilacqa, and S. Seri Preterm infants with video-EEG confirmed seizures: outcome at 30 months of age Brain Dev 30 2008 20 30
17. A.A. Fanaroff, B.J. Stoll, L.L. Wright, W.A. Carlo, R.A. Ehrenkranz, and A.R. Stark Trends in morbidity and mortality for very low birthweight infants Am J Obstet Gynecol 196 2007 147.e1 147.e8
18. G.R. Alexander, J.H. Himes, R.B. Kaufman, J. Mor, and M. Kogan A United States national reference for fetal growth Obstet Gynecol 87 1996 163 168
19. L.A. Papile, J. Burstein, R. Burstein, and H. Koffler Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1500 gm J Pediatr 92 1978 529 534
20. M.J. Bell, J.L. Ternberg, R.D. Feigin, J.P. Keating, R. Marshall, and L. Barton Neonatal necrotizing enterocolitis: therapeutic decisions based on clinical staging Ann Surg 187 1978 1 7
21. J.J. Volpe Neonatal seizures: current concepts and classification Pediatrics 84 1989 422 428
22. N. Bayley Bayley Scales of Infant Development II 1993 Psychological Corp San Antonio, Texas
23. J. Volpe Neurology of the newborn 5th ed. 2008 WB Saunders Company Philadelphia
24. M.P. Thiebault-Eybalin, A. Lortie, and L. Carmant Neonatal seizures: do they damage the brain? Pediatr Neurol 40 2009 175 180
25. G.L. Holmes, and Y. Ben-Ari Seizures in the developing brain: perhaps not so benign after all Neuron 21 1998 1231 1234
26. B.K. McCabe, D.C. Silveira, M.R. Cilio, B.H. Cha, X. Liu, and Y. Sogawa Reduced neurogenesis after neonatal seizures J Neurosci 21 2001 2094 2103
27. P. Bittigau, M. Sifringer, K. Genz, E. Reith, D. Pospischil, and S. Govindarajalu Antiepileptic drugs and apoptotic neurodegeneration in the developing brain Proc Nat Acad Sci U S A 99 2002 15089 15094 (Pubitemid 35334614)
28. F.S. Silverstein, F.E. Jensen, T. Inder, L. Hellstrom-Westas, D. Hirtz, and D.M. Ferriero Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop report J Pediatr 153 2008 12 15
29. B. Vohr, M. Msall, D. Wilson, L. Wright, S. McDonald, and W. Poole Spectrum of gross motor function in extremely low birth weight children with cerebral palsy at 18 months of age Pediatrics 116 2005 123 129
30. G.M. Ronen, D. Buckley, S. Penney, and D.L. Streiner Long-term prognosis in children with neonatal seizures: a population-based study Neurology 69 2007 1816 1822
31. H.C. Glass, D. Glidden, R.J. Jeremy, A.J. Barkovich, D.M. Ferriero, and S.P. Miller Clinical neonatal seizures are independently associated with outcome in infants at risk for hypoxic-ischemic injury J Pediatr 155 2009 318 323
32. D. Kohelet, R. Schochat, A. Lusky, and B. Reichman Risk factors for neonatal seizures in very low birthweight infants: population-based survey J Child Neurol 19 2004 123 128
33. D.M. Murray, G.B. Boylan, I. Ali, C.A. Ryan, B.P. Murphy, and S. Connolly Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures Arch Dis Child Fetal Neonat Ed 93 2008 F187 F191
34. D.K. Shah, J. Zempel, T. Barton, K. Lukas, and T.E. Inder Electrographic seizures in preterm infants during the first week of life are associated with cerebral injury Pediatr Res 67 2010 102 106