Reply to Bauer et al.: Murine pDC recognition of vaccinia viral DNA is mediated by TLR8

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 36, 2010, Pages

  Martinez, Jennifer ^a   Yang, Yiping ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9;

ANTIGEN RECOGNITION; CELL ACTIVATION; CROSS REACTION; CYTOKINE PRODUCTION; DNA VIRUS; INNATE IMMUNITY; LETTER; MOLECULAR RECOGNITION; MOUSEPOX; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; VACCINIA VIRUS; VIRUS INFECTION;

MURINAE;

EID: 77958021510     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009858107     Document Type: Letter

References (6)

1. Martinez J, Huang X, Yang Y (2010) Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA. Proc Natl Acad Sci USA 107:6442-6447.
2. Bauer S, et al. (2010) A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC? Proc Natl Acad Sci USA 107:E139.
3. Samuelsson C, et al. (2008) Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection. J Clin Invest 118:1776-1784. (Pubitemid 351632380)
4. Waibler Z, et al. (2007) Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses. J Virol 81:12102-12110. (Pubitemid 350085825)
5. Edwards AD, et al. (2003) Toll-like receptor expression in murine DC subsets: Lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines. Eur J Immunol 33:827-833.
6. Colamonici OR, Domanski P, Sweitzer SM, Larner A, Buller RM (1995) Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon alpha transmembrane signaling. J Biol Chem 270:15974-15978.