Increased risk for acute lymphoblastic leukemia in children with cytochrome P450 A1(CYP1A1)- and NAD(P)H:quinone oxidoreductase 1 (NQO1)-inherited gene variants

Acta Haematologica

Volumn 124, Issue 3, 2010, Pages 182-184

  Yamaguti, Gabriela G ^a   Lourenço, Gustavo J ^a   Silveira, Vanessa S ^c   Tone, Luiz G ^c   Lopes, Luiz F ^b   Lima, Carmen S P ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A; OXIDOREDUCTASE; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CANCER RISK; CHILD; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

BRAZIL; CASE-CONTROL STUDIES; CHILD, PRESCHOOL; CYTOCHROME P-450 CYP1A1; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; INFANT; MALE; METABOLIC DETOXICATION, DRUG; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); POLYCYCLIC HYDROCARBONS, AROMATIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RISK FACTORS;

EID: 77958015683     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000320275     Document Type: Article

References (12)

1. Steffen C, Auclerc MF, Auvrignon A, Baruchel A, Kebaili K, Lambilliotte A, Leverger G, Sommelet D, Vilmer E, Hémon D, Clavel J: Acute childhood leukaemia and environmental exposure to potential sources of benzene and other hydrocarbons: a case-control study. Occup Environ Med 2004;61:773-778.
2. Joseph T, Kusumakumary P, Chacko P, Abraham A, Pillai MR: Genetic polymorphism of CYP1A1, CYP2D6, GSTM1 and GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children. Pediatr Blood Cancer 2004;43:560-567.
3. Clavel J, Bellec S, Rebouissou S, Ménégaux F, Feunteun J, Bonaïti-Pellié C, Baruchel A, Kebaili K, Lambilliotte A, Leverger G, Sommelet D, Lescoeur B, Beaune P, Hémon D, Loriot MA: Childhood leukaemia, polymorphisms of metabolism enzyme genes, and interactions with maternal tobacco, coffee and alcohol consumption during pregnancy. Eur J Cancer Prev 2005;14:531-540.
4. Pakakasama S, Mukda E, Sasanakul W, Kadegasem P, Udomsubpayakul U, Thithapandha A, Hongeng S: Polymorphisms of drug-metabolizing enzymes and risk of childhood acute lymphoblastic leukemia. Am J Hematol 2005;79:202-205.
5. Aydin-Sayitoglu M, Hatirnaz O, Erensoy N, Ozbek U: Role of CYP2D6, CYP1A1, CYP2E1, GSTT1 and GSTM1 genes in the susceptibility to acute leukemias. Am J Hematol 2006;84:162-170.
6. Smith MT, Wang Y, Skibola CF, Slater DJ, Lo Nigro L, Nowell PC, Lange BJ, Felix CA: Low NAD (P) H: quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children. Blood 2002;100:4590-4593.
7. Kracht T, Schrappe M, Strehl S, Reiter A, Eisner HA, Trka J, Cario G, Viehmann S, Harbott J, Borkhardt A, Metzler M, Langer T, Repp R, Marschalek R, Welte K, Haas OA, Stanulla M: NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms. Haematologica 2004;89:1492-1497.
8. Sirma S, Agaoglu L, Yildiz I, Cayli D, Horgusluoglu E, Anak S, Yuksel L, Unuvar A, Celkan T, Apak H, Karakas Z, Devecioglu O, Ozbek U: NAD (P) H:quinone oxidoreductase 1 null genotype is not associated with pediatric de novo acute leukemia. Pediatr Blood Cancer 2004;43:568-570.
9. Eguchi-Ishimae M, Eguchi M, Ishii E, Knight D, Sadakane Y, Isoyama K, Yabe H, Mizutani S, Greaves M: The association of a distinctive allele of NAD (P) H: quinone oxidoreductase with pediatric acute lymphoblastic leukemias with MLL fusion genes in Japan. Haematologica 2005;90:1511-1515.
10. Lanciotti M, Dufour C, Corral L, Di Michele P, Pigullo S, De Rossi G, Basso G, Leszl A, Luciani M, Lo Nigro L, Micalizzi C, Valsecchi MG, Biondi A, Haupt R: Genetic polymorphism of NAD (P) H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements. Leukemia 2005;19:214-216.
11. Yeoh AE, Lu Y, Chan JY, Chan YH, Ariffin H, Kham SK, Quah TC: Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group. Leuk Res 2010;34:276-283.
12. Larson RA, Wang Y, Banerjee M, Wiemels J, Hartford C, Le Beau MM, Smith MT: Prevalence of the inactivating 609C3T polymorphism in the NAD (P) H: quinone oxidoreductase (NQOl) gene in patients with primary and therapy-related myeloid leukemia. Blood 1999;94:803-807.