Antiplasmodial activity and cytotxicity of semi purified fractions from Zacthoxylum zanthoxyloïdes Lam. bark of trunk

International Journal of Pharmacology

Volumn 6, Issue 6, 2010, Pages 921-925

  Gansane, A ^a   Sanon, S ^a   Ouattara, P L ^a   Hutter, S ^b   Olhvier, E ^b   Azas, N ^b   Traore, A ^a   Traore, A S ^c   Guissou, I P ^c   Nebie, I ^a   Sirima, B S ^a,d  

^a Burkina Faso   (Burkina Faso)

^b AIX MARSEILLE UNIVERSITY   (France)

^c UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

^d Centre de Recherche Action en Sante GRAS   (Burkina Faso)

Author keywords

Antiplasmodial activity; Chromatograpty; Cytotoxicity; Fractions; Zanthoxylum zanthoxyloides

Indexed keywords

ALKALOID; CHLOROQUINE; DOXORUBICIN; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG; ZANTHOXYLUM ZANTHOXYLOIDES EXTRACT;

ANTIMICROBIAL ACTIVITY; ARTICLE; BARK; BURKINA FASO; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG PURIFICATION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM; SOLVENT EXTRACTION; ZANTHOXYLUM; ZANTHOXYLUM ZANTHOXYLOIDES;

EID: 77958013393     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2010.921.925     Document Type: Article

References (13)

1. Deharo, E., G. Bourdy, C. Quenevo, V. Munoz, G. Ruiz and M. Sauvain., 2001. A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part V. Evaluation of the antimalarial activity of plants used by the Tacana Indians. J. Ethnopharmacol., 77: 91-98.
2. Gansane, A., I. Nebie, I. Soulama, A. Tiono and A. Diarrax et al.2009a. Change of antimalarial first line treatment in burkina faso in 2005. Bull. Soc. Pathol. Exot, 102: 31-35.
3. Gansane, A., S. Sanon, L.P. Ouattara, A. Traore and S. Hutter et al, 2009b. Antiplasmodial activity and toxicity of crude extracts from alternatives parts of plants widely used for the treatment of malaria in burkina faso: Contribution for their preservation. Parasitol. Res., 106: 335-340.
4. Kassim, O.O., M. Loyevsky, B. Elliott, A. Geall, H. Amonoo and V.R. Gordeuk, 2005. Effects of root extracts of Fagara zanthoxyloides on the in vitro growth and stage distribution of Plasmodium falciparum. Antimicrob. Agents Chemother., 49: 264-268.
5. Messmer, W.M., M. Tin-Wa, H.H. Fong, C. Bevelle, N.R. Farnsworth, D.J. Abraham and J. Trojanek, 1972. Fagaronine, a new tumor inhibitor isolated from Fagara zanthoxyloides Lam. (Rutaceae). J. Pharm. Sci.,61: 1858-1859.
6. Ouattara, B., L. Angenot, P. Guissou, P. Fondu and J. Dubois et al, 2004. LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam. Phytochemistry, 65: 1145-1151.
7. Ouattara, B., O. Jansen, L. Angenot, LP. Guissou, M. Fredench, P. Fondu and M. Tits, 2009. Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae). Phytomedicine, 16: 125-129.
8. Prado, S., S. Michel, F. Tillequin, M. Koch and B. Pfeiffer et al., 2004. Synthesis and cytotoxic activity of benzo[c][l,7] and [l,8]phenanfhrolines analogues of nitidine and fagaronine. Bioorg. Med. Chem., 12: 3943-3953.
9. Rogier, C. and J.F. Trape, 1999. Malaria: Organizations, network and new initiatives. Med. Trop., 59: 55-56.
10. Rowe, A.K., S.Y. Rowe, RW. Snow, E.L. Korenromp, and J.R. Schellenberg, et al, 2006. 2006 The burden of malaria mortality among African children in the year 2000. Int. J. Epidemiol, 35: 691-704.
11. Snow, R.W., M. Craig, U. Deichmann, and K. Marsh, 1999. Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population. Bull. World Health Organ., 77: 624-640.
12. Trager, W. and J. Jensen, 1976. Human malaria parasites in continuous culture. Sciences, 193: 673-675.
13. Traore, A., A.I. Derme, S. Sanon, A. Gansane, Y. Ouattara, I. Nebie and S.B. Sirima, 2009. Connaissances efhnobotaniques et pratiques phytofherapeutiques des tradipraticiens de sante de la Comoe pour le traitement du paludisme: Processus d'une recherche scientifique de nouveaux antipaludiques au Burkina Faso. Efhnopharmacologia, 43: 35-46.