Social interaction modulates autonomic, inflammatory, and depressive-like responses to cardiac arrest and cardiopulmonary resuscitation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 37, 2010, Pages 16342-16347

  Norman, Greg J ^a   Zhang, Ning ^a   Morris, John S ^a   Karelina, Kate ^a   Berntson, Gary G ^a   DeVries, A Courtney ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Depression; Ischemia; Parasympathetic; Sympathetic

Indexed keywords

CD11B ANTIGEN; CORTICOSTERONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BRAIN ISCHEMIA; CONTROLLED STUDY; DEPRESSION; FORCED SWIMMING TEST; HEART ARREST; HEART RATE VARIABILITY; HIPPOCAMPUS; INFLAMMATION; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OPEN FIELD TEST; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESUSCITATION; SOCIAL INTERACTION; SOCIAL ISOLATION; ANIMAL; C57BL MOUSE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOPHYSIOLOGY; SOCIAL BEHAVIOR;

ANIMALIA; MUS;

ANIMALS; CARDIOPULMONARY RESUSCITATION; CYTOKINES; DEPRESSION; FEMALE; GENE EXPRESSION REGULATION; HEART ARREST; INFLAMMATION MEDIATORS; MALE; MICE; MICE, INBRED C57BL; OVARIECTOMY; RNA, MESSENGER; SOCIAL BEHAVIOR;

EID: 77957998100     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007583107     Document Type: Article

References (38)

1. Rosamond W, et al. (2007) Heart disease and stroke statistics -2007 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115:e69-e171. (Pubitemid 46226160)
2. Garza AG, et al. (2009) Improved patient survival using a modified resuscitation protocol for out-of-hospital cardiac arrest. Circulation 119:2597-2605.
3. Drezner JA (2009) Preparing for sudden cardiac arrest - the essential role of automated external defibrillators in athletic medicine: A critical review. Br J Sports Med 43:702-707.
4. Tiainen M, et al. (2009) Arrhythmias and heart rate variability during and after therapeutic hypothermia for cardiac arrest. Crit Care Med 37:403-409.
5. Cronberg T, Lilja G, Rundgren M, Friberg H, Widner H (2009) Long-term neurological outcome after cardiac arrest and therapeutic hypothermia. Resuscitation 80:1119-1123.
6. Adrie C, et al. (2002) Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome. Circulation 106:562-568.
7. Offner H, Vandenbark AA, Hurn PD (2009) Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression. Neuroscience 158:1098-1111.
8. Sunnerhagen KS, Johansson O, Herlitz J, Grimby G (1996) Life after cardiac arrest; a retrospective study. Resuscitation 31:135-140.
9. House JS, Landis KR, Umberson D (1988) Social relationships and health. Science 241:540-545.
10. Frasure-Smith N, et al. (2009) Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure. Circulation 120:134-140.
11. Harukuni I, Bhardwaj A (2006) Mechanisms of brain injury after global cerebral ischemia. Neurol Clin 24:1-21.
12. Qiu J, et al. (2008) Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab 28:927-938. (Pubitemid 351589627)
13. Micieli G, Cavallini A (2008) The autonomic nervous system and ischemic stroke: A reciprocal interdependence. Clin Auton Res 18:308-317.
14. Neigh GN, et al. (2009) Cardiac arrest and cardiopulmonary resuscitation dysregulates the hypothalamic-pituitary-adrenal axis. J Cereb Blood Flow Metab 29:1673-1682.
15. Balanescu S, Corlan AD, Dorobantu M, Gherasim L (2004) Prognostic value of heart rate variability after acute myocardial infarction. Med Sci Monit 10:CR307-CR315.
16. Thayer JF, Lane RD (2007) The role of vagal function in the risk for cardiovascular disease and mortality. Biol Psychol 74:224-242.
17. Moynihan J, Kruszewska B, Madden K, Callahan T (2004) Sympathetic nervous system regulation of immunity. J Neuroimmunol 147:87-90. (Pubitemid 38114953)
18. Tracey KJ (2009) Reflex control of immunity. Nat Rev Immunol 9:418-428.
19. Offner H, et al. (2006) Experimental stroke induces massive, rapid activation of the peripheral immune system. J Cereb Blood Flow Metab 26:654-665.
20. Neigh GN, et al. (2009) Anxiety after cardiac arrest/cardiopulmonary resuscitation: Exacerbated by stress and prevented by minocycline. Stroke 40:3601-3607.
21. Empana JP, et al. (2006) Clinical depression and risk of out-of-hospital cardiac arrest. Arch Intern Med 166:195-200.
22. Norman GJ, et al. (2010) Social interaction prevents the development of depressive-like behavior post nerve injury in mice: A potential role for oxytocin. Psychosom Med 72:519-526.
23. Weil ZM, et al. (2008) Social isolation potentiates cell death and inflammatory responses after global ischemia. Mol Psychiatry 13:913-915.
24. Karelina K, et al. (2009) Social isolation alters neuroinflammatory response to stroke. Proc Natl Acad Sci USA 106:5895-5900.
25. Yenari M, Kitagawa K, Lyden P, Perez-Pinzon M (2008) Metabolic downregulation: A key to successful neuroprotection? Stroke 39:2910-2917.
26. Corbett D, Thornhill J (2000) Temperature modulation (hypothermic and hyperthermic conditions) and its influence on histological and behavioral outcomes following cerebral ischemia. Brain Pathol 10:145-152.
27. Berntson GG, Cacioppo JT, Quigley KS (1994) Autonomic cardiac control. I. Estimation and validation from pharmacological blockades. Psychophysiology 31:572-585.
28. Weil ZM, Norman GJ, DeVries AC, Berntson GG, Nelson RJ (2009) Photoperiod alters autonomic regulation of the heart. Proc Natl Acad Sci USA 106:4525-4530.
29. Karelina K, Norman GJ, Zhang N, DeVries AC (2009) Social contact influences histological and behavioral outcomes following cerebral ischemia. Exp Neurol 220:276-282.
30. Kiecolt-Glaser JK, et al. (1984) Psychosocial modifiers of immunocompetence in medical students. Psychosom Med 46:7-14. (Pubitemid 14183488)
31. Cole SW, et al. (2007) Social regulation of gene expression in human leukocytes. Genome Biol 8:R189.
32. Waje-Andreassen U, et al. (2005) IL-6: An early marker for outcome in acute ischemic stroke. Acta Neurol Scand 111:360-365.
33. Berntson GG, Norman GJ, Hawkley LC, Cacioppo JT (2008) Cardiac autonomic balance versus cardiac regulatory capacity. Psychophysiology 45:643-652.
34. Pohjasvaara T, et al. (1998) Frequency and clinical determinants of poststroke depression. Stroke 29:2311-2317. (Pubitemid 28511949)
35. Berg A, Palomäki H, Lehtihalmes M, Lönnqvist J, Kaste M (2003) Poststroke depression: An 18-month follow-up. Stroke 34:138-143.
36. Berntson GG, et al. (1997) Heart rate variability: Origins, methods, and interpretive caveats. Psychophysiology 34:623-648.
37. Howden R, et al. (2008) The genetic contribution to heart rate and heart rate variability in quiescent mice. Am J Physiol Heart Circ Physiol 295:H59-H68.
38. Porsolt RD (2000) Animal models of depression: Utility for transgenic research. Rev Neurosci 11:53-58. (Pubitemid 30006576)