Impaired glomerular and tubular antioxidative defense mechanisms in nephrotic syndrome

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 4, 2010, Pages

  Granqvist, Anna ^a   Nilsson, Ulf A ^a   Ebefors, Kerstin ^a   Haraldsson, Börje ^a   Nyström, Jenny ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Oxidative stress; Puromycin aminonucleoside

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE 3; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; THIOREDOXIN REDUCTASE 1; ANTIOXIDANT; GLUTATHIONE PEROXIDASE; PUROMYCIN AMINONUCLEOSIDE; THIOREDOXIN REDUCTASE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEFENSE MECHANISM; ELECTRON SPIN RESONANCE; FEMALE; GLOMERULUS; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; KIDNEY TUBULE; LIPID PEROXIDATION; MALE; NEPHROTIC SYNDROME; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; ANIMAL; BIOPSY; CASE CONTROL STUDY; CHEMICALLY INDUCED; DISEASE MODEL; ENZYMOLOGY; GLOMERULUS FILTRATION RATE; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADULT; AGED; ANIMALS; ANTIOXIDANTS; BIOPSY; CASE-CONTROL STUDIES; CATALASE; DISEASE MODELS, ANIMAL; FEMALE; GLOMERULAR FILTRATION RATE; GLUTATHIONE PEROXIDASE; HUMANS; KIDNEY GLOMERULUS; KIDNEY TUBULES; LIPID PEROXIDATION; MALE; MIDDLE AGED; NEPHROTIC SYNDROME; OXIDATIVE STRESS; PUROMYCIN AMINONUCLEOSIDE; RATS; RATS, SPRAGUE-DAWLEY; THIOREDOXIN-DISULFIDE REDUCTASE;

EID: 77957989613     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00124.2010     Document Type: Article

References (43)

1. Albertini R, Passi A, Abuja PM, De Luca G. The effect of glycosaminoglycans and proteoglycans on lipid peroxidation. Int J Mol Med 6:129-136, 2000.
2. Beaman M, Birtwistle R, Howie AJ, Michael J, Adu D. The role of superoxide anion and hydrogen peroxide in glomerular injury induced by puromycin aminonucleoside in rats. Clin Sci (Lond) 73: 329-332, 1987. (Pubitemid 17095113)
3. Beckman JS, Minor RL Jr, White CW, Repine JE, Rosen GM, Freeman BA. Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance. J Biol Chem 263: 6884-6892, 1988.
4. Bjornson Granqvist A, Ebefors K, Saleem MA, Mathieson PW, Haraldsson B, Nystrom JS. Podocyte proteoglycan synthesis is involved in the development of nephrotic syndrome. Am J Physiol Renal Physiol 291: F722-F730, 2006. (Pubitemid 44506968)
5. Boute N, Gribouval O, Roselli S, Benessy F, Lee H, Fuchshuber A, Dahan K, Gubler MC, Niaudet P, Antignac C. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat Genet 24: 349-354, 2000.
6. Bulucu F, Vural A, Aydin A, Sayal A. Oxidative stress status in adults with nephrotic syndrome. Clin Nephrol 53: 169-173, 2000. (Pubitemid 30141326)
7. Candiano G, Musante L, Petretto A, Bruschi M, Santucci L, Urbani A, Scolari F, Gusmano R, Carraro M, Zennaro C, Vincenti F, Ghiggeri GM. Proteomics of plasma and urine in primary nephrotic syndrome in children. Contrib Nephrol 160: 17-28, 2008.
8. Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 59: 527-605, 1979.
9. Chen HC, Guh JY, Lai YH. Alterations of glomerular and extracellular glutathione peroxidase levels in patients and rats with focal segmental glomerulosclerosis. J Lab Clin Med 137: 279-283, 2001.
10. Datta PK, Koukouritaki SB, Hopp KA, Lianos EA. Heme oxygenase-1 induction attenuates inducible nitric oxide synthase expression and proteinuria in glomerulonephritis. J Am Soc Nephrol 10: 2540-2550, 1999.
11. Diamond JR, Bonventre JV, Karnovsky MJ. A role for oxygen free radicals in aminonucleoside nephrosis. Kidney Int 29: 478-483, 1986. (Pubitemid 16129057)
12. El-Far MA, Bakr MA, Farahat SE, Abd El-Fattah EA. Glutathione peroxidase activity in patients with renal disorders. Clin Expl Nephrol 9:127-131, 2005. (Pubitemid 40875101)
13. Erel O. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem 37: 277-285, 2004. (Pubitemid 38314881)
14. Gao F, Koenitzer JR, Tobolewski JM, Jiang D, Liang J, Noble PW, Oury TD. Extracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronan. J Biol Chem 283:6058-6066, 2008.
15. Guan N, Ding J, Zhang J, Yang J. Expression of nephrin, podocin, alpha-actinin, and WT1 in children with nephrotic syndrome. Pediatr Nephrol 18: 1122-1127, 2003. (Pubitemid 37406858)
16. Guo J, Ananthakrishnan R, Qu W, Lu Y, Reiniger N, Zeng S, Ma W, Rosario R, Yan SF, Ramasamy R, D'Agati V, Schmidt AM. RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis. J Am Soc Nephrol 19: 961-972, 2008.
17. Gwinner W, Deters-Evers U, Brandes RP, Kubat B, Koch KM, Pape M, Olbricht CJ. Antioxidant-oxidant balance in the glomerulus and proximal tubule of the rat kidney. J Physiol 509: 599-606, 1998. (Pubitemid 28287016)
18. Gwinner W, Landmesser U, Brandes RP, Kubat B, Plasger J, Eberhard O, Koch KM, Olbricht CJ. Reactive oxygen species and antioxidant defense in puromycin aminonucleoside glomerulopathy. J Am Soc Nephrol 8: 1722-1731, 1997. (Pubitemid 27475873)
19. Kashihara N, Watanabe Y, Makino H, Wallner EI, Kanwar YS. Selective decreased de novo synthesis of glomerular proteoglycans under the influence of reactive oxygen species. Proc Natl Acad Sci USA 89:6309-6313, 1992.
20. Kestila M, Lenkkeri U, Mannikko M, Lamerdin J, McCready P, Putaala H, Ruotsalainen V, Morita T, Nissinen M, Herva R, Kashtan CE, Peltonen L, Holmberg C, Olsen A, Tryggvason K. Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Mol Cell 1: 575-582, 1998.
21. Kliment CR, Tobolewski JM, Manni ML, Tan RJ, Enghild J, Oury TD. Extracellular superoxide dismutase protects against matrix degradation of heparin sulfate in the lung. Antioxid Redox Signal 10: 261-268, 2008.
22. Liu H, Bigler SA, Henegar JR, Baliga R. Cytochrome P450 2B1 mediates oxidant injury in puromycin-induced nephrotic syndrome. Kidney Int 62: 868-876, 2002.
23. Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37: 517-554, 1997.
24. Maser RL, Magenheimer BS, Calvet JP. Mouse plasma glutathione peroxidase. cDNA sequence analysis and renal proximal tubular expression and secretion. J Biol Chem 269: 27066-27073, 1994.
25. Miner JH, Morello R, Andrews KL, Li C, Antignac C, Shaw AS, Lee B. Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation. J Clin Invest 109: 1065-1072, 2002.
26. Nakakura H, Ashida A, Hirano K, Tamai H. Oxidative stress in a rat model of nephrosis can be quantified by electron spin resonance. Pediatr Nephrol 19: 266-270, 2004.
27. Oberley TD, Verwiebe E, Zhong W, Kang SW, Rhee SG. Localization of the thioredoxin system in normal rat kidney. Free Radic Biol Med 30:412-424, 2001.
28. Ogino T, Inoue M, Ando Y, Awai M, Maeda H, Morino Y. Chemical modification of superoxide dismutase. Extension of plasma half life of the enzyme through its reversible binding to the circulating albumin. Int J Pept Protein Res 32: 153-159, 1988.
29. Park SJ, Lee BH, Kim DJ. Identification of proteins that interact with podocin using the yeast 2-hybrid system. Yonsei Med J 50: 273-279, 2009.
30. Pollak MR. The genetic basis of FSGS and steroid-resistant nephrosis. Semin Nephrol 23: 141-146, 2003.
31. Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 233: 357-363, 1994.
32. Ricardo SD, Bertram JF, Ryan GB. Antioxidants protect podocyte foot processes in puromycin aminonucleoside-treated rats. J Am Soc Nephrol 4:1974-1986, 1994.
33. Rincon J, Romero M, Viera N, Pedreanez A, Mosquera J. Increased oxidative stress and apoptosis in acute puromycin aminonucleoside nephrosis. Int J Exp Pathol 85: 25-33, 2004.
34. Rundlof AK, Carlsten M, Giacobini MM, Arner ES. Prominent expression of the selenoprotein thioredoxin reductase in the medullary rays of the rat kidney and thioredoxin reductase mRNA variants differing at the 5′ untranslated region. Biochem J 347: 661-668, 2000.
35. Shah SV, Baricos WH, Basci A. Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites. J Clin Invest 79: 25-31, 1987.
36. Sies H. Role of reactive oxygen species in biological processes. Klin Wochenschr 69: 965-968, 1991.
37. Tryggvason K. Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm. J Am Soc Nephrol 10:2440-2445, 1999.
38. Turi S, Nemeth I, Torkos A, Saghy L, Varga I, Matkovics B, Nagy J. Oxidative stress and antioxidant defense mechanism in glomerular diseases. Free Radic Biol Med 22: 161-168, 1997.
39. Ueda A, Hirayama A, Nagase S, Inoue M, Oteki T, Aoyama M, Yokoyama H. In vivo detection of intrinsic reactive oxygen species using acyl-protected hydroxylamine in puromycin nephrosis. Free Radic Res 41:823-828, 2007.
40. Whitin JC, Bhamre S, Tham DM, Cohen HJ. Extracellular glutathione peroxidase is secreted basolaterally by human renal proximal tubule cells. Am J Physiol Renal Physiol 283: F20-F28, 2002.
41. Yagi K. A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 15: 212-216, 1976.
42. Yoshimura S, Suemizu H, Nomoto Y, Sakai H, Katsuoka Y, Kawamura N, Moriuchi T. Plasma glutathione peroxidase deficiency caused by renal dysfunction. Nephron 73: 207-211, 1996.
43. Zachwieja J, Bobkowski W, Zaniew M, Dobrowolska-Zachwieja A, Lewandowska-Stachowiak M, Siwinska A. Apoptosis and antioxidant defense in the nephrotic syndrome. Pediatr Nephrol 18: 1116-1121, 2003.