Recovery of upper limb function after cerebellar stroke: Lesion symptom mapping and arm kinematics

Stroke

Volumn 41, Issue 10, 2010, Pages 2191-2200

  Konczak, Jürgen ^a   Pierscianek, Daniela ^b   Hirsiger, Sarah ^a,c   Bultmann, Uta ^b   Schoch, Beate ^b   Gizewski, Elke R ^b,d   Timmann, Dagmar ^b   Maschke, Matthias ^e   Frings, Markus ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c ETH ZURICH   (Switzerland)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

^e Brüderkrankenhaus ^*  (Germany)

Author keywords

arm movement; ataxia; brain imaging; cerebellum; human

Indexed keywords

ACUTE DISEASE; ADULT; AGED; ARM MOVEMENT; ARTICLE; BRADYKINESIA; BRAIN ARTERY; CEREBELLUM INFARCTION; CEREBELLUM NUCLEUS; CEREBELLUM VERMIS; CLINICAL ARTICLE; CONTROLLED STUDY; CONVALESCENCE; FEMALE; FINGER; FOLLOW UP; HAND FUNCTION; HUMAN; KINEMATICS; MALE; MOTOR COORDINATION; MOTOR PERFORMANCE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTERIOR CEREBELLAR ARTERY; PRIORITY JOURNAL; SUPERIOR CEREBELLAR ARTERY; ARM; BIOMECHANICS; BRAIN MAPPING; CEREBELLUM; CEREBELLUM DISEASE; CEREBROVASCULAR ACCIDENT; IMAGE PROCESSING; MIDDLE AGED; MOVEMENT (PHYSIOLOGY); PATHOPHYSIOLOGY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ARM; BIOMECHANICS; BRAIN MAPPING; CEREBELLAR DISEASES; CEREBELLUM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MOVEMENT; RECOVERY OF FUNCTION; STROKE; BIOMECHANICAL PHENOMENA;

EID: 77957976756     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.110.583641     Document Type: Article

References (37)

1. Tohgi H, Takahashi S, Chiba K, Hirata Y. Cerebellar infarction. Clinical and neuroimaging analysis in 293 patients. The tohoku cerebellar infarction study group. Stroke. 1993;24:1697-1701.
2. Weimar C, Roth MP, Zillessen G, Glahn J, Wimmer ML, Busse O, Haberl RL, Diener HC. Complications following acute ischemic stroke. Eur Neurol. 2002;48:133-140.
3. Holmes G. The symptoms of acute cerebellar injuries due to gunshot injuries. Brain. 1917;40:463-535.
4. Edlow JA, Newman-Toker DE, Savitz SI. Diagnosis and initial management of cerebellar infarction. Lancet Neurol. 2008;7:951-964.
5. Babinski J De l'asynergie cerebelleuse. Revue Neurologique. 1899; 7:806-816.
6. Babinski J. Asynergie et inertie cerebelleuses. Revue Neurologique. 1906; 14:685-686.
7. Sander T, Sprenger A, Neumann G, Machner B, Gottschalk S, Rambold H, Helmchen C. Vergence deficits in patients with cerebellar lesions. Brain. 2009;132:103-115.
8. Ogawa K, Suzuki Y, Kamei S, Mizutani T. [a case of cerebellar infarction with pure dysarthria.] Rinsho Shinkeigaku. 2004;44:111-113.
9. Karaci R, Ozturk S, Ozbakir S, Cansaran N. Evaluation of language functions in acute cerebellar vascular diseases. J Stroke Cerebrovasc Dis. 2008;17:251-256.
10. Manto M, Jacquy J, Hildebrand J, Godaux E. Recovery of hypermetria after a cerebellar stroke occurs as a multistage process. Ann Neurol. 1995;38:437-445.
11. Brown SH, Hefter H, Mertens M, Freund HJ. Disturbances in human arm trajectory due to mild cerebellar dysfunction. J Neurol Neurosurg Psych. 1990;53:306-313.
12. Topka H, Konczak J, Dichgans J. Coordination of multi-joint arm movements in cerebellar ataxia: Analysis of hand and angular kinematics. Exp Brain Res. 1998;119:483-492.
13. Bastian AJ. Cerebellar limb ataxia: Abnormal control of self-generated and external forces. Ann N Y Acad Sci. 2002;978:16-27.
14. Bastian AJ, Martin TA, Keating JG, Thach WT. Cerebellar ataxia: Abnormal control of interaction torques across multiple joints. J Neuro-physiol. 1996;76:492-509.
15. Topka H, Konczak J, Schneider K, Boose A, Dichgans J. Multi-joint arm movements in cerebellar ataxia: Abnormal control of movement dynamics. Exp Brain Res. 1998;119:493-503.
16. Konczak J, Timmann D. The effect of damage to the cerebellum on sensorimotor and cognitive function in children and adolescents. Neurosci Biobehav Rev. 2007;31:1101-1113. (Pubitemid 350160946)
17. Timmann D, Konczak J, Ilg W, Donchin O, Hermsdorfer J, Gizewski ER, Schoch B. Current advances in lesion-symptom mapping of the human cerebellum. Neuroscience. 2009;162:836-851.
18. Konczak J, Schoch B, Dimitrova A, Gizewski E, Timmann D. Functional recovery of children and adolescents after cerebellar tumour resection. Brain. 2005;128:1428-1441.
19. Schoch B, Konczak J, Dimitrova A, Gizewski ER, Wieland R, Timmann D. Impact of surgery and adjuvant therapy on balance function in children and adolescents with cerebellar tumors. Neuropediatrics. 2006;37: 350-358.
20. Schoch B, Dimitrova A, Gizewski ER, Timmann D. Functional localization in the human cerebellum based on voxelwise statistical analysis: A study of 90 patients. Neuroimage. 2006;30:36-51.
21. Oldfield RC. The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia. 1971;9:97-113.
22. Trouillas P, Takayanagi T, Hallett M, Currier RD, Subramony SH, Wessel K, Bryer A, Diener HC, Massaquoi S, Gomez CM, Coutinho P, Ben Hamida M, Campanella G, Filla A, Schut L, Timann D, Honnorat J, Nighoghossian N, Manyam B. International cooperative ataxia rating scale for pharmacological assessment of the cerebellar syndrome. The ataxia neuropharmacology committee of the world federation of neurology. J Neurol Sci. 1997;145:205-211.
23. Dimitrova A, Weber J, Redies C, Kindsvater K, Maschke M, Kolb FP, Forsting M, Diener HC, Timmann D. MRI atlas of the human cerebellar nuclei. Neuroimage. 2002;17:240-255.
24. Schmahmann JD, Dojon J, Toga AW, Petrides M, Evans AC. MRI atlas of the human cerebellum. San Diego, CA: Academic Press; 2000.
25. Larsell O. Anatomy of the nervous system. New York, NY: Appleton-Century-Crofts; 1951.
26. Tatu L, Moulin T, Bogousslavsky J, Duvernoy H. Arterial territories of human brain: Brainstem and cerebellum. Neurology. 1996;47:1125-1135.
27. Hore J, Wild B, Diener HC. Cerebellar dysmetria at the elbow, wrist, and fingers. J Neurophysiol. 1991;65:563-571.
28. Timmann D, Richter S, Bestmann S, Kalveram KT, Konczak J. Predictive control of muscle responses to arm perturbations in cerebellar patients. J Neurol Neurosurg Psych. 2000;69:345-352.
29. Wild B, Dichgans J. Cerebellar ataxia in ataxic hemiparesis? A kinematic and emg analysis. Mov Disord. 1993;8:363-366.
30. Cirstea MC, Levin MF. Compensatory strategies for reaching in stroke. Brain. 2000;123(Pt 5):940-953.
31. Nowak DA. The impact of stroke on the performance of grasping: Usefulness of kinetic and kinematic motion analysis. Neurosci Biobehav Rev. 2008;32:1439-1450.
32. Growdon JH, Chambers WW, Liu CN. An experimental study of cere-bellar dyskinesia in the rhesus monkey. Brain. 1967;90:603-632.
33. Mackel R. The role of the monkey sensory cortex in the recovery from cerebellar injury. Exp Brain Res. 1987;66:638-652.
34. Mason R, Miller LE, Baker JF, Houk JC. Organization of reaching and grasping movements in the primate cerebellar nuclei as revealed by focal muscimol inactivations. J Neurophysiol. 1998;79:537-544.
35. Grodd W, Hulsmann E, Lotze M, Wildgruber D, Erb M. Sensorimotor mapping of the human cerebellum: fMRI evidence of somatotopic organization. Hum Brain Mapp. 2001;13:55-73.
36. Manni E, Petrosini L. A century of cerebellar somatotopy: A debated representation. Nat Rev Neurosci. 2004;5:241-249.
37. Trott JR, Apps R, Armstrong DM. Topographical organisation within the cerebellar nucleocortical projection to the paravermal cortex of lobule vb/c in the cat. Exp Brain Res. 1990;80:415-428.