Construction of recombinant human nerve growth factor beta adenovirus and evaluation of its function an in vitro and in vivo study

Neural Regeneration Research

Volumn 5, Issue 16, 2010, Pages 1261-1269

  Gao, En Feng ^a   Choi, Si Ho ^b   Sung, Mi Ae ^c   Li, Bo Han ^c   Jabaiti, Samir ^d   Yoo, Sang Bae ^c   Kim, Sung June ^e   Kim, Soung Min ^c   Jahng, Jeong Won ^c   Lee, Jong Ho ^c  

^a CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c BK 21 Plus   (South Korea)

^d JORDAN UNIVERSITY HOSPITAL   (Jordan)

^e Seoul National University   (South Korea)

Author keywords

Adenoviral vector; Fibroblasts; Hek293 cells; Myoblasts; Nerve growth factor; Peripheral nerve regeneration; Schwann cell

Indexed keywords

ADENOVIRUS VECTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; NERVE GROWTH FACTOR BETA SUBUNIT; NEUROTROPHIN RECEPTOR P75; RECOMBINANT NERVE GROWTH FACTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CELL STRAIN 3T3; CELL STRAIN HEK293; CELL STRUCTURE; CONTROLLED STUDY; DNA SEQUENCE; DRUG EFFECT; DRUG MECHANISM; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE OVEREXPRESSION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR CLONING; MYOBLAST; NERVE CELL LESION; NERVE FIBER GROWTH; NERVE REGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; RESTRICTION MAPPING; RNA ISOLATION; SCHWANN CELL; STRUCTURE ANALYSIS; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

EID: 77957974759     PISSN: 16735374     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2010.16.011     Document Type: Article

References (43)

1. Boyd JG, Gordon T. Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury. Mol Neurobiol. 2003;27:277-324.
2. Griffin CG, Letourneau PC. Rapid retraction of neurites by sensory neurons in response to increased concentrations of nerve growth factor. J Cell Biol. 1980;86:156-161.
3. Kaechi K, Ikegami R, Nakamura N, et al. 4-Methylcatechol, an inducer of nerve growth factor synthesis, enhances peripheral nerve regeneration across nerve gaps. J Pharmacol Exp Ther. 1995;272:1300-1304.
4. Lee AC, Yu VM, Lowe JB, et al. Controlled release of nerve growth factor enhances sciatic nerve regeneration. Exp Neurol. 2003;184:295-303.
5. Rush RA, Mayo R, Zettler C. The regulation of nerve growth factor synthesis and delivery to peripheral neurons. Pharmacol Ther. 1995;65:93-123.
6. Heumann R, Korsching S, Bandtlow C, et al. Changes of nerve growth factor synthesis in non-neuronal cells in response to sciatic nerve transection. J Cell Biol. 1987;104:1623-1631.
7. Heumann R, Lindholm D, Bandtlow C, et al. Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A. 1987;84: 8735-8739.
8. Anton ES, Weskamp G, Reichardt LF, et al. Nerve growth factor and its low-affinity receptor promote Schwann cell migration. Proc Natl Acad Sci U S A. 1994;91:2795-2799.
9. Thomas, PK: The cellular response to nerve injury. III. The effect of repeated crush injuries. J Anat. 1970;106:463-468.
10. Liu HM, Lei HY, Kao KP. Correlation between NGF levels in wound chamber fluid and cytological localization of NGF and NGF receptor in axotomized rat sciatic nerve. Exp Neurol. 1999;132: 24-32.
11. Verma IM, Weitzman MD. Gene therapy: twenty-first century medicine. Annu Rev Biochem. 2005;74:711-738.
12. Yi Y, Hahm SH, Lee KH. Retroviral gene therapy: safety issues and possible solutions. Curr Gene Ther. 2005;5:25-35.
13. Haddada H, Cordier L, Perricaudet M. Gene therapy using adenovirus vectors. Curr Top Microbiol Immunol. 1995;199: 297-306.
14. Smith GM, Romero MI. Adenoviral-mediated gene transfer to enhance neuronal survival, growth, and regeneration. J Neurosci Res. 1999;55:147-157.
15. Brody SL, Crystal RG. Adenovirus-mediated in vivo gene transfer. Ann NY Acad Sci. 1994;716:90-101.
16. Le Gal La Salle G, Robert JJ, Berrard S, et al. An adenovirus vector for gene transfer into neurons and glia in the brain. Science. 1993;259:988-990.
17. Klein RL, Hamby ME, Gong Y, et al. Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain. Exp Neurol. 2002;176:66-74.
18. Abe K, Setoguchi Y, Hayashi T, et al. In vivo adenovirus-mediated gene transfer and the expression in ischemic and reperfused rat brain. Brain Res. 1997;763:191-201.
19. Rush RA, Mayo R, Zettler C. The regulation of nerve growth factor synthesis and delivery to peripheral neurons. Pharmacol Ther. 1995;65:93-123.
20. Huber AB, Ehrengruber MU, Schwab ME, et al. Adenoviral gene transfer to the injured spinal cord of the adult rat. Eur J Neurosci. 2000;12:3437-3434.
21. Koda M, Hashimoto M, Murakami M, et al. Adenovirus vector-mediated in vivo gene transfer of brain-derived neurotrophic factor (BDNF) promotes rubrospinal axonal regeneration and functional recovery after complete transection of the adult rat spinal cord. J Neurotrauma. 2004;21:329-337.
22. Jimenez JC, Tyson DR, Dhar S, et al. Human embryonic kidney cells (HEK-293 cells): characterization and dose-response relationship for modulated release of nerve growth factor for nerve regeneration. Plast Reconstr Surg. 2004;113:605-610.
23. Joung I, Kim HS, Hong JS, et al. Effective gene transfer into regenerating sciatic nerves by adenoviral vectors: potentials for gene therapy of peripheral nerve injury. Mol Cells. 2000;31: 540-545.
24. Martijn R, Tannemaat M, Gerard J, et al. Genetic modification of human sural nerve segments by a lentiviral vector encoding nerve growth factor. Neurosurgery. 2007;61:1286-1296.
25. Yin Q, Kemp GJ, Yu LG, et al. Neurotrophin-4 delivered by fibrin glue promotes peripheral nerve regeneration. Muscle Nerve. 2001;24:345-351.
26. Barras FM, Pasche P, Bouche N, et al. Glial cell line-derived neurotrophic factor released by synthetic guidance channels promotes facial nerve regeneration in the rat. J Neurosci Res. 2002;70:746-755.
27. Everill B, Kocsis JD. Nerve growth factor maintains potassium conductance after nerve injury in adult cutaneous afferent dorsal root ganglion neurons. Neuroscience. 2000;100:417-422.
28. Rahimi O, Juliano SL. Transplants of NGF-secreting fibroblasts restore stimulus-evoked activity in barrel cortex of basal- forebrain-lesioned rats. J Neurophysiol. 2001;86:2081-2096.
29. Shoemaker SE, Kudwa AE, Isaacson LG. Sympathetic ingrowth to the trigeminal ganglion following intracerebroventricular infusion of nerve growth factor. Brain Res. 2002;956:136-148.
30. Pagnotta A, Tos P, Fornaro M, et al. Neurotrophins and their receptors in early axonal regeneration along muscle-vein- combined grafts. Microsurgery. 2002;22:300-303.
31. Menderes A, Yilmaz M, Vayvada H, et al. Effects of nerve growth factor on the neurotization of denervated muscles. Ann Plast Surg. 2002;48:415-422.
32. Skaper SD. Nerve growth factor: A neurokine orchestrating neuroimmune-endocrine functions. Mol Neurobiol. 2001;24: 183-199.
33. Dekker AJ, Winkler J, Ray J, et al. Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis. Neuroscience. 1994;60:299-309.
34. Dekker AJ, Fagan AM, Gage FH, et al. Effects of brain-derived neurotrophic factor and nerve growth factor on remaining neurons in the lesioned nucleus basalis magnocellularis. Brain Res. 1994; 639:149-155.
35. Dekker AJ, Gage FH, Thal LJ. Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: Evaluation of the involvement of different neurotransmitter systems. Neuroscience. 1992;48:111-119.
36. Sakiyama-Elbert SE, Hubbell JA. Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix. J Control Release. 2000;69:149-154.
37. Patrick CW Jr, Zheng B, Wu X, et al. Muristerone A-induced nerve growth factor release from genetically engineered human dermal fibroblasts for peripheral nerve tissue engineering. Tissue Eng. 2001;7:303-311.
38. Rosenberg MB, Friedmann T, Robertson RC, et al. Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science. 1988;242:1575-1578.
39. Hoffman D, Breakefield XO, Short MP, et al. Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF. Exp Neurol. 1993;122:100-106.
40. Xiao B, Li Q, Feng B, et al. Expression of recombinant human nerve growth factor beta in milk of goats by recombinant replication-defective adenovirus. Appl Biochem Biotechnol. 2009; 157:357-366.
41. Xiao B, Li Q, Feng B, et al. High-level expression of recombinant human nerve growth factor beta in milk of nontransgenic rabbits. J Biosci Bioeng. 2008;105:327-334.
42. Cenciarelli C, Budoni M, Mercanti D, et al. In vitro analysis of mouse neural stem cells genetically modified to stably express human NGF by a novel multigenic viral expression system. Neurol Res. 2006;28:505-512.
43. Kim SM, Lee JH, Kim NY, et al. Improved protocol for Schwann cell isolation and proliferation from rat dorsal root ganglia in vitro. Korean J Maxillofac Plast Reconstru Surg. 2003;25:265-272.