메뉴 건너뛰기




Volumn 45, Issue 10, 2010, Pages 1546-1552

Plasma levels of IL-7 and IL-15 in the first month after myeloablative BMT are predictive biomarkers of both acute GVHD and relapse

Author keywords

acute GVHD; allo SCT; IL 15; IL 7; relapse

Indexed keywords

BIOLOGICAL MARKER; CYCLOSPORIN; INTERLEUKIN 15; INTERLEUKIN 7; METHOTREXATE;

EID: 77957965347     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2010.13     Document Type: Article
Times cited : (86)

References (40)
  • 1
    • 2342484524 scopus 로고    scopus 로고
    • Molecules and mechanisms of the graft-versus-leukaemia effect
    • Bleakley M, Riddell SR. Molecules and mechanisms of the graft-versus-leukaemia effect. Nat Rev Cancer 2004; 4: 371-380.
    • (2004) Nat Rev Cancer , vol.4 , pp. 371-380
    • Bleakley, M.1    Riddell, S.R.2
  • 2
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik WD. Graft-versus-host disease. Nat Rev Immunol 2007; 7: 340-352.
    • (2007) Nat Rev Immunol , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 3
    • 38949100377 scopus 로고    scopus 로고
    • Up-regulation of NK cell activating receptors following allogeneic hematopoietic stem cell transplantation under a lymphodepleting reduced intensity regimen is asso-ciated with elevated IL-15 levels
    • Boyiadzis M, Memon S, Carson J, Allen K, Szczepanski MJ, Vance BA et al. Up-regulation of NK cell activating receptors following allogeneic hematopoietic stem cell transplantation under a lymphodepleting reduced intensity regimen is asso-ciated with elevated IL-15 levels. Biol Blood Marrow Trans-plant 2008; 14: 290-300.
    • (2008) Biol Blood Marrow Trans-plant , vol.14 , pp. 290-300
    • Boyiadzis, M.1    Memon, S.2    Carson, J.3    Allen, K.4    Szczepanski, M.J.5    Vance, B.A.6
  • 4
    • 57249094209 scopus 로고    scopus 로고
    • Reconstitution of the immune system after hematopoietic stem cell transplantation in humans
    • Storek J, Geddes M, Khan F, Huard B, Helg C, Chalandon Y et al. Reconstitution of the immune system after hematopoietic stem cell transplantation in humans. Semin Immunopathol 2008; 30: 425-437.
    • (2008) Semin Immunopathol , vol.30 , pp. 425-437
    • Storek, J.1    Geddes, M.2    Khan, F.3    Huard, B.4    Helg, C.5    Chalandon, Y.6
  • 5
    • 18144394761 scopus 로고    scopus 로고
    • Immune reconstitution following hematopoietic progenitor cell transplantation: Challenges for the future
    • Fry TJ, Mackall CL. Immune reconstitution following hematopoietic progenitor cell transplantation: challenges for the future. Bone Marrow Transplant 2005; 35(Suppl 1): S53-S57.
    • (2005) Bone Marrow Transplant , vol.35 , Issue.SUPPL. 1
    • Fry, T.J.1    MacKall, C.L.2
  • 6
    • 36549014534 scopus 로고    scopus 로고
    • T cell immune reconstitution following lymphodepletion
    • Williams KM, Hakim FT, Gress RE. T cell immune reconstitution following lymphodepletion. Semin Immunol 2007; 19: 318-330.
    • (2007) Semin Immunol , vol.19 , pp. 318-330
    • Williams, K.M.1    Hakim, F.T.2    Gress, R.E.3
  • 7
    • 33747642227 scopus 로고    scopus 로고
    • IL-7 in allogeneic transplant: Clinical promise and potential pitfalls
    • Snyder KM, Mackall CL, Fry TJ. IL-7 in allogeneic transplant: clinical promise and potential pitfalls. Leuk Lymphoma 2006; 47: 1222-1228.
    • (2006) Leuk Lymphoma , vol.47 , pp. 1222-1228
    • Snyder, K.M.1    MacKall, C.L.2    Fry, T.J.3
  • 8
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: From lymphopoiesis to peripheral T cell maintenance
    • Fry TJ, Mackall CL. The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J Immunol 2005; 174: 6571-6576.
    • (2005) J Immunol , vol.174 , pp. 6571-6576
    • Fry, T.J.1    MacKall, C.L.2
  • 9
    • 11244262924 scopus 로고    scopus 로고
    • Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation
    • Alpdogan O, Eng JM, Muriglan SJ, Willis LM, Hubbard VM, Tjoe KH et al. Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation. Blood 2005; 105: 865-873.
    • (2005) Blood , vol.105 , pp. 865-873
    • Alpdogan, O.1    Eng, J.M.2    Muriglan, S.J.3    Willis, L.M.4    Hubbard, V.M.5    Tjoe, K.H.6
  • 10
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin 15: Biology and relevance to human disease
    • Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood 2001; 97: 14-32.
    • (2001) Blood , vol.97 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 11
    • 57449097567 scopus 로고    scopus 로고
    • Association of serum interleukin-7 levels with the development of acute graft-versus-host disease
    • Dean RM, Fry T, Mackall C, Steinberg SM, Hakim F, Fowler D et al. Association of serum interleukin-7 levels with the development of acute graft-versus-host disease. J Clin Oncol 2008; 26: 5735-5741.
    • (2008) J Clin Oncol , vol.26 , pp. 5735-5741
    • Dean, R.M.1    Fry, T.2    MacKall, C.3    Steinberg, S.M.4    Hakim, F.5    Fowler, D.6
  • 12
    • 0032053098 scopus 로고    scopus 로고
    • Prolonged secretion of IL-15 in patients with severe forms of acute graft-versus-host disease after allogeneic bone marrow transplantation in children
    • Kumaki S, Minegishi M, Fujie H, Sasahara Y, Ohashi Y, Tsuchiya S et al. Prolonged secretion of IL-15 in patients with severe forms of acute graft-versus-host disease after allogeneic bone marrow transplantation in children. Int J Hematol 1998; 67: 307-312.
    • (1998) Int J Hematol , vol.67 , pp. 307-312
    • Kumaki, S.1    Minegishi, M.2    Fujie, H.3    Sasahara, Y.4    Ohashi, Y.5    Tsuchiya, S.6
  • 13
    • 0034954448 scopus 로고    scopus 로고
    • Kinetics of plasma cytokines after hematopoietic stem cell transplantation from unrelated donors: The ratio of plasma IL-10/sTNFR level as a potential prognostic marker in severe acute graft-versus-host disease
    • Sakata N, Yasui M, Okamura T, Inoue M, Yumura-Yagi K, Kawa K. Kinetics of plasma cytokines after hematopoietic stem cell transplantation from unrelated donors: the ratio of plasma IL-10/sTNFR level as a potential prognostic marker in severe acute graft-versus-host disease. Bone Marrow Trans-plant 2001; 27: 1153-1161.
    • (2001) Bone Marrow Trans-plant , vol.27 , pp. 1153-1161
    • Sakata, N.1    Yasui, M.2    Okamura, T.3    Inoue, M.4    Yumura-Yagi, K.5    Kawa, K.6
  • 14
    • 0347384007 scopus 로고    scopus 로고
    • Elevated serum interleukin-15 level in acute graft-versus-host disease after hematopoietic cell transplantation
    • Chik KW, Li K, Pong H, Shing MM, Li CK, Yuen PM. Elevated serum interleukin-15 level in acute graft-versus-host disease after hematopoietic cell transplantation. J Pediatr Hematol Oncol 2003; 25: 960-964.
    • (2003) J Pediatr Hematol Oncol , vol.25 , pp. 960-964
    • Chik, K.W.1    Li, K.2    Pong, H.3    Shing, M.M.4    Li, C.K.5    Yuen, P.M.6
  • 15
    • 49649107807 scopus 로고    scopus 로고
    • low NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation
    • low NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation. J Immunol 2008; 181: 2227-2237.
    • (2008) J Immunol , vol.181 , pp. 2227-2237
    • Dulphy, N.1    Haas, P.2    Busson, M.3    Belhadj, S.4    Peffault De Latour, R.5    Robin, M.6
  • 16
    • 0032867565 scopus 로고    scopus 로고
    • Immunological reconstitution and correlation of circulating serum inflammatory mediators/cytokines with the incidence of acute graft-versus-host disease during the first 100 days following unrelated umbilical cord blood transplant-ation
    • Abu-Ghosh A, Goldman S, Slone V, van de Ven C, Suen Y, Murphy L et al. Immunological reconstitution and correlation of circulating serum inflammatory mediators/cytokines with the incidence of acute graft-versus-host disease during the first 100 days following unrelated umbilical cord blood transplant-ation. Bone Marrow Transplant 1999; 24: 535-544.
    • (1999) Bone Marrow Transplant , vol.24 , pp. 535-544
    • Abu-Ghosh, A.1    Goldman, S.2    Slone, V.3    Van De Ven, C.4    Suen, Y.5    Murphy, L.6
  • 17
    • 0032946001 scopus 로고    scopus 로고
    • Serum levels of IL-7 in bone marrow transplant recipients: Relationship to clinical characteristics and lymphocyte count
    • Bolotin E, Annett G, Parkman R, Weinberg K. Serum levels of IL-7 in bone marrow transplant recipients: relationship to clinical characteristics and lymphocyte count. Bone Marrow Transplant 1999; 23: 783-788.
    • (1999) Bone Marrow Transplant , vol.23 , pp. 783-788
    • Bolotin, E.1    Annett, G.2    Parkman, R.3    Weinberg, K.4
  • 18
    • 33747597069 scopus 로고    scopus 로고
    • + T cells expressing the lymph node-homing chemokine receptor CCR7 increases incidence and severity of acute graft-versus-host disease in patients undergoing allogeneic stem cell transplantation for hematological malignancy
    • + T cells expressing the lymph node-homing chemokine receptor CCR7 increases incidence and severity of acute graft-versus-host disease in patients undergoing allogeneic stem cell transplantation for hematological malignancy. Leukemia 2006; 20: 1557-1565.
    • (2006) Leukemia , vol.20 , pp. 1557-1565
    • Yakoub-Agha, I.1    Saule, P.2    Depil, S.3    Micol, J.B.4    Grutzmacher, C.5    Boulanger-Villard, F.6
  • 19
    • 60549117539 scopus 로고    scopus 로고
    • IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
    • Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med 2009; 206: 25-34.
    • (2009) J Exp Med , vol.206 , pp. 25-34
    • Huntington, N.D.1    Legrand, N.2    Alves, N.L.3    Jaron, B.4    Weijer, K.5    Plet, A.6
  • 23
    • 46949105036 scopus 로고    scopus 로고
    • Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
    • Sportes C, Hakim FT, Memon SA, Zhang H, Chua KS, Brown MR et al. Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets. J Exp Med 2008; 205: 1701-1714.
    • (2008) J Exp Med , vol.205 , pp. 1701-1714
    • Sportes, C.1    Hakim, F.T.2    Memon, S.A.3    Zhang, H.4    Chua, K.S.5    Brown, M.R.6
  • 24
    • 1342345057 scopus 로고    scopus 로고
    • Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease
    • Gendelman M, Hecht T, Logan B, Vodanovic-Jankovic S, Komorowski R, Drobyski WR. Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease. J Immunol 2004; 172: 3328-3336.
    • (2004) J Immunol , vol.172 , pp. 3328-3336
    • Gendelman, M.1    Hecht, T.2    Logan, B.3    Vodanovic-Jankovic, S.4    Komorowski, R.5    Drobyski, W.R.6
  • 26
    • 34548680962 scopus 로고    scopus 로고
    • Absolute lymphocyte count on day 30 is a surrogate for robust hematopoietic recovery and strongly predicts outcome after T cell-depleted allogeneic stem cell transplantation
    • Savani BN, Mielke S, Rezvani K, Montero A, Yong AS, Wish L et al. Absolute lymphocyte count on day 30 is a surrogate for robust hematopoietic recovery and strongly predicts outcome after T cell-depleted allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2007; 13: 1216-1223.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 1216-1223
    • Savani, B.N.1    Mielke, S.2    Rezvani, K.3    Montero, A.4    Yong, A.S.5    Wish, L.6
  • 29
    • 69149083248 scopus 로고    scopus 로고
    • Contribution of naive and memory T-cell populations to the human alloimmune response
    • Macedo C, Orkis EA, Popescu I, Elinoff BD, Zeevi A, Shapiro R et al. Contribution of naive and memory T-cell populations to the human alloimmune response. Am J Transplant 2009; 9: 2057-2066.
    • (2009) Am J Transplant , vol.9 , pp. 2057-2066
    • MacEdo, C.1    Orkis, E.A.2    Popescu, I.3    Elinoff, B.D.4    Zeevi, A.5    Shapiro, R.6
  • 31
    • 33645293492 scopus 로고    scopus 로고
    • Genetic polymorphisms in the genes encoding human interleukin-7 receptor-α: Prognostic signifi-cance in allogeneic stem cell transplantation
    • Shamim Z, Ryder LP, Heilmann C, Madsen H, Lauersen H, Andersen PK et al. Genetic polymorphisms in the genes encoding human interleukin-7 receptor-α: prognostic signifi-cance in allogeneic stem cell transplantation. Bone Marrow Transplant 2006; 37: 485-491.
    • (2006) Bone Marrow Transplant , vol.37 , pp. 485-491
    • Shamim, Z.1    Ryder, L.P.2    Heilmann, C.3    Madsen, H.4    Lauersen, H.5    Andersen, P.K.6
  • 32
    • 37449004090 scopus 로고    scopus 로고
    • + T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease
    • + T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease. JImmunol 2007; 179: 3305-3314.
    • (2007) JImmunol , vol.179 , pp. 3305-3314
    • Zhang, Y.1    Hexner, E.2    Frank, D.3    Emerson, S.G.4
  • 33
    • 3843124199 scopus 로고    scopus 로고
    • Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function
    • Chu YW, Memon SA, Sharrow SO, Hakim FT, Eckhaus M, Lucas PJ et al. Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function. Blood 2004; 104: 1110-1119.
    • (2004) Blood , vol.104 , pp. 1110-1119
    • Chu, Y.W.1    Memon, S.A.2    Sharrow, S.O.3    Hakim, F.T.4    Eckhaus, M.5    Lucas, P.J.6
  • 34
    • 0344465968 scopus 로고    scopus 로고
    • Factors affecting reconstitution of the T cell compartment in allogeneic haematopoietic cell transplant recipients
    • Fallen PR, McGreavey L, Madrigal JA, Potter M, Ethell M, Prentice HG et al. Factors affecting reconstitution of the T cell compartment in allogeneic haematopoietic cell transplant recipients. Bone Marrow Transplant 2003; 32: 1001-1014.
    • (2003) Bone Marrow Transplant , vol.32 , pp. 1001-1014
    • Fallen, P.R.1    McGreavey, L.2    Madrigal, J.A.3    Potter, M.4    Ethell, M.5    Prentice, H.G.6
  • 35
    • 34247163959 scopus 로고    scopus 로고
    • Allogeneic marrow stem-cell transplantation from human leukocyte antigen-identical siblings versus human leukocyte antigen-allelic-matched unrelated donors (10/10) in patients with standard-risk hematologic malignancy: A prospective study from the French Society of Bone Marrow Transplantation and Cell Therapy
    • Yakoub-Agha I, Mesnil F, Kuentz M, Boiron JM, Ifrah N, Milpied N et al. Allogeneic marrow stem-cell transplantation from human leukocyte antigen-identical siblings versus human leukocyte antigen-allelic-matched unrelated donors (10/10) in patients with standard-risk hematologic malignancy: a prospective study from the French Society of Bone Marrow Transplantation and Cell Therapy. J Clin Oncol 2006; 24: 5695-5702.
    • (2006) J Clin Oncol , vol.24 , pp. 5695-5702
    • Yakoub-Agha, I.1    Mesnil, F.2    Kuentz, M.3    Boiron, J.M.4    Ifrah, N.5    Milpied, N.6
  • 37
    • 34250890678 scopus 로고    scopus 로고
    • IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8T cells
    • Sandau MM, Winstead CJ, Jameson SC. IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8T cells. J Immunol 2007; 179: 120-125.
    • (2007) J Immunol , vol.179 , pp. 120-125
    • Sandau, M.M.1    Winstead, C.J.2    Jameson, S.C.3
  • 38
    • 33751572484 scopus 로고    scopus 로고
    • + memory T cells mediated by IL-15 and its induced cytokines
    • + memory T cells mediated by IL-15 and its induced cytokines. JImmunol 2006; 177: 7802-7810.
    • (2006) JImmunol , vol.177 , pp. 7802-7810
    • Chiu, W.K.1    Fann, M.2    Weng, N.P.3
  • 39
    • 39349110365 scopus 로고    scopus 로고
    • Early lymphocyte recovery post-allogeneic hematopoietic stem cell transplantation is associated with significant graft-versus-leukemia effect without increase in graft-versus-host disease in pediatric acute lymphoblastic leukemia
    • Ishaqi MK, Afzal S, Dupuis A, Doyle J, Gassas A. Early lymphocyte recovery post-allogeneic hematopoietic stem cell transplantation is associated with significant graft-versus-leukemia effect without increase in graft-versus-host disease in pediatric acute lymphoblastic leukemia. Bone Marrow Transplant 2008; 41: 245-252.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 245-252
    • Ishaqi, M.K.1    Afzal, S.2    Dupuis, A.3    Doyle, J.4    Gassas, A.5
  • 40
    • 34548798651 scopus 로고    scopus 로고
    • Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lympho-blastic leukemia
    • Savani BN, Mielke S, Adams S, Uribe M, Rezvani K, Yong AS et al. Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lympho-blastic leukemia. Leukemia 2007; 21: 2145-2152.
    • (2007) Leukemia , vol.21 , pp. 2145-2152
    • Savani, B.N.1    Mielke, S.2    Adams, S.3    Uribe, M.4    Rezvani, K.5    Yong, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.