Nerve growth factor and pain

New England Journal of Medicine

Volumn 363, Issue 16, 2010, Pages 1572-1573

  Wood, John N ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; TANEZUMAB; MONOCLONAL ANTIBODY; NERVE GROWTH FACTOR RECEPTOR;

ANALGESIA; DRUG ACTIVITY; DRUG POTENCY; EDITORIAL; FOOD AND DRUG ADMINISTRATION; HEADACHE; HUMAN; NERVE BLOCK; OSTEOARTHRITIS; PARESTHESIA; PRIORITY JOURNAL; TREATMENT INDICATION; ANTAGONISTS AND INHIBITORS; COMPLICATION; DISEASE COURSE; KNEE PROSTHESIS; OSTEOARTHRITIS, KNEE; PAIN;

ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; DISEASE PROGRESSION; HUMANS; KNEE PROSTHESIS; OSTEOARTHRITIS, KNEE; PAIN; RECEPTOR, NERVE GROWTH FACTOR;

EID: 77957963249     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1004416     Document Type: Editorial

References (10)

1. Lane NE, Schnitzer TJ, Birbara CA, et al. Tanezumab for the treatment of pain from osteoarthritis of the knee. N Engl J Med 2010;363:1521-31.
2. Obata K, Katsura H, Sakurai J, et al. Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury. J Neurosci 2006;26:11974-86. (Pubitemid 44772108)
3. Bergmann I, Reiter R, Toyka KV, Koltzenburg M. Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75. Neurosci Lett 1998;255:87-90.
4. Holtzman DM, Kilbridge J, Li Y, et al. TrkA expression in the CNS: evidence for the existence of several novel NGF-responsive CNS neurons. J Neurosci 1995;15:1567-76.
5. Lewin GR, Rueff A, Mendell LM. Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur J Neurosci 1994;6:1903-12.
6. Levi-Montalcini R. Growth control of nerve cells by a protein factor and its antiserum: discovery of this factor may provide new leads to understanding of some neurogenetic processes. Science 1964;143:105-10.
7. Urschel BA, Brown PN, Hulsebosch CE. Differential effects on sensory nerve processes and behavioral alterations in the rat after treatment with antibodies to nerve growth factor. Exp Neurol 1991;114:44-52.
8. Taiwo YO, Levine JD, Burch RM, Woo JE, Mobley WC. Hyperalgesia induced in the rat by the amino-terminal octapeptide of nerve growth factor. Proc Natl Acad Sci U S A 1991;88:5144-8.
9. Hefti FF, Rosenthal A, Walicke PA, et al. Novel class of pain drugs based on antagonism of NGF. Trends Pharmacol Sci 2006;27:85-91.
10. McMahon SB, Bennett DL, Priestley JV, Shelton DL. The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule. Nat Med 1995;1:774-80.