Honokiol inhibits the progression of collagen-induced arthritis by reducing levels of pro-inflammatory cytokines and matrix metalloproteinases and blocking oxidative tissue damage

Journal of Pharmacological Sciences

Volumn 114, Issue 1, 2010, Pages 69-78

  Kim, Ki Rim ^a,b   Park, Kwang Kyun ^a,b   Chun, Kyung Soo ^c   Chung, Won Yoon ^a,b  

^a Yonsei University College of Dentistry   (South Korea)

^b Yonsei University   (South Korea)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Interleukin 1 (IL 1 ); Matrix metalloproteinase (MMP); Oxidative damage; Tumor necrosis factor a (TNF a); Type II collagen induced arthritis

Indexed keywords

3 NITROTYROSINE; CATALASE; COLLAGEN TYPE 2; COLLAGENASE 3; GELATINASE B; HONOKIOL; INTERLEUKIN 17; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MALONALDEHYDE; OSTEOCLAST DIFFERENTIATION FACTOR; REACTIVE OXYGEN METABOLITE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; STROMELYSIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG ISOLATION; HISTOPATHOLOGY; KIDNEY PARENCHYMA; LIPID PEROXIDATION; LIVER PARENCHYMA; MAGNOLIACEAE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PAW EDEMA; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SPLEEN CELL; TISSUE INJURY;

EID: 77957957246     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10070FP     Document Type: Article

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