The origin of ovarian cancer - Is it getting clearer?

New England Journal of Medicine

Volumn 363, Issue 16, 2010, Pages 1574-1575

  Birrer, Michael J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; ARID1A PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

AT RICH INTERACTIVE DOMAIN 1A GENE; CANCER CELL CULTURE; CANCER GROWTH; DISEASE ASSOCIATION; EDITORIAL; ENDOMETRIOSIS; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; OVARY CANCER; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TUMOR GENE; TUMOR SUPPRESSOR GENE; ADENOCARCINOMA; COMPLICATION; FEMALE; GENE EXPRESSION PROFILING; GENETICS; MUTATION; OVARY TUMOR;

ADENOCARCINOMA, CLEAR CELL; ENDOMETRIOSIS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MUTATION; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 77957941319     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1009527     Document Type: Editorial

References (12)

1. Sampson J. Endometrial carcinoma of the ovary, arising in endometrial tissue in that organ. Arch Surg 1925;10:1-72.
2. Sainz de la Cuesta R, Eichhorn JH, Rice LW, Fuller AF Jr, Nikrui N, Goff BA. Histologic transformation of benign endometriosis to early epithelial ovarian cancer. Gynecol Oncol 1996;60:238-44. (Pubitemid 26058768)
3. Levanon K, Crum C, Drapkin R. New insights into the pathogenesis of serous ovarian cancer and its clinical impact. J Clin Oncol 2008;26:5284-93.
4. Wiegand KC, Shah SP, Al-Agha OM, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010;363:1532-43.
5. Shah SP, Kobel M, Senz J, et al. Mutation of FOXL2 in granulosa-cell tumors of the ovary. N Engl J Med 2009;360:2719-29.
6. Obata K, Hoshiai H. Common genetic changes between endometriosis and ovarian cancer. Gynecol Obstet Invest 2000;50: Suppl 1:39-43.
7. Viganó P, Somigliana E, Chiodo I, Abbiati A, Vercellini P. Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis. Hum Reprod Update 2006;12:77-89.
8. Dinulescu DM, Ince TA, Quade BJ, Shafer SA, Crowley D, Jacks T. Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer. Nat Med 2005;11:63-70.
9. Huang J, Zhao YL, Li Y, Fletcher JA, Xiao S. Genomic and functional evidence for an ARID1A tumor suppressor role. Genes Chromosomes Cancer 2007;46:745-50. (Pubitemid 46912345)
10. Wang X, Nagl NG Jr, Flowers S, Zweitzig D, Dallas PB, Moran E. Expression of p270 (ARID1A), a component of human SWI/SNF complexes, in human tumors. Int J Cancer 2004;112:636.
11. Lemon B, Inouye C, King DS, Tjian R. Selectivity of chromatin- remodelling cofactors for ligand-activated transcription. Nature 2001;414:924-8. (Pubitemid 34024745)
12. Li XS, Trojer P, Matsumura T, Treisman JE, Tanese N. Mammalian SWI/SNF - a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B. Mol Cell Biol 2010;30:1673-88.