In vitro contrast-enhanced ultrasound measurements of capillary microcirculation: Comparison between polymer- and phospholipid-shelled microbubbles

Ultrasonics

Volumn 51, Issue 1, 2011, Pages 40-48

  Grishenkov, Dmitry ^a   Kari, Leif ^a   Brodin, Lars Åke ^a   Brismar, Torkel B ^b   Paradossi, Gaio ^c  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Capillary; Contrast agents; Perfusion; Phospholipid; Polymer

Indexed keywords

APPLICATION OF POLYMERS; BACK-SCATTERED; BACKSCATTERED SIGNAL; BLOOD POOL; CAPILLARY; CAPILLARY MODEL; CONTRAST AGENTS; CONTRAST ENHANCED ULTRASOUND; IN-VITRO; LINEARLY PROPORTIONAL; MICRO-BUBBLE; MICROBUBBLES; MICROTUBE; NOVEL POLYMERS; OPTIMAL CONCENTRATION; OPTIMAL LEVEL; PEAK AMPLITUDE; PERFUSION; PERFUSION IMAGING; POLYMER SHELL; TARGETED IMAGING; TIME CONSTANTS; TIME INTERVAL; ULTRASOUND CONTRAST AGENT; VESSEL PHANTOM;

BLOOD VESSELS; CONCENTRATION (PROCESS); DRUG THERAPY; ELECTROMAGNETIC WAVE BACKSCATTERING; EXPERIMENTS; EXPONENTIAL FUNCTIONS; GENE THERAPY; GENETIC ENGINEERING; LAKES; MICROCIRCULATION; OPTIMIZATION; PHOSPHOLIPIDS; ULTRASONICS;

POLYMERS;

ALBUMINOID; CONTRAST AGENT BR1; CONTRAST MEDIUM; FLUOROCARBON; PERFLUTREN; PHOSPHOLIPID; POLYMER; SULFUR HEXAFLUORIDE;

ARTICLE; CAPILLARY; CHEMISTRY; COMPARATIVE STUDY; ECHOGRAPHY; HUMAN; IMAGE QUALITY; IN VITRO STUDY; MICROBUBBLE; MICROCIRCULATION; TRANSDUCER;

ALBUMINS; CAPILLARIES; CONTRAST MEDIA; FLUOROCARBONS; HUMANS; MICROBUBBLES; MICROCIRCULATION; PHANTOMS, IMAGING; PHOSPHOLIPIDS; POLYMERS; SULFUR HEXAFLUORIDE; TRANSDUCERS;

EID: 77957931904     PISSN: 0041624X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultras.2010.05.006     Document Type: Article

References (27)

1. F. Cavalieri, A. El Hamassi, E. Chiessi, G. Paradossi, R. Villa, and N. Zaffaroni Tethering functional ligands onto shell of ultrasound active polymeric microbubbles Biomacromolecules 7 2006 604 611
2. E.G. Schutt, D.H. Klein, R.M. Mattrey, and J.G. Riess Injectable microbubbles as contrast agents for diagnostic ultrasound imaging: the key role of perfluorochemicals Angew. Chem. Int. Ed. 42 2003 3218 3235
3. F. Cavalieri, A. El Hamassi, E. Chiessi, and G. Paradossi Stable polymeric microballoons as multifunctional device for biomedical uses: synthesis and characterization Langmuir 21 2005 8758 8764
4. J.D. Lathia, L. Leodore, and M.A. Wheatley Polymeric contrast agent with targeting potential Ultrasonics 42 2004 763 768
5. M. Ressner, L.A. Brodin, T. Jansson, L. Hoff, P. Ask, and B. Janerot-Sjoberg Effects of ultrasound contrast agents on Doppler tissue velocity estimation J. Am. Soc. Echocardiogr. 19 2006 154 164
6. A.G. Fraser, N. Payne, C.F. Mädler, B. Janerot-Sjöberg, B. Lind, R.M. Grocott-Mason, A.A. Ionescu, N. Florescu, U. Wilkenshoff, P. Lancellotti, M. Wütte, and L.A. Brodin MYDISE investigators. Feasibility and reproducibility of off-line tissue Doppler measurement of regional myocardial function during dobutamine stress echocardiography Eur. J. Echocardiogr. 4 2003 43 53
7. M.J. Monaghan Stress myocardial contrast echocardiography Heart 89 2003 1391 1393
8. D. Grishenkov, C. Pecorari, T.B. Brismar, and G. Paradossi Characterization of acoustic properties of PVA-shelled ultrasound contrast agents: linear properties (part I) Ultrasound Med. Biol. 35 2009 1127 1138
9. S. Liu, and D.F. O'Brien Stable polymeric nanoballoons: lyophilization and rehydration of cross-linked liposomes J. Am. Chem. Soc. 124 2002 6037 6042
10. K. Wei, A.R. Jayaweera, S. Firoozan, A. Linka, D.M. Skyba, and S. Kaul Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion Circulation 97 1998 473 483
11. M. Schneider Characteristics of SonoVue Echocardiography 16 1999 743 746
12. IEEE Std 790-1989 IEEE Guide for Medical Ultrasound Field Parameter Measurements, The Institute of Electrical and Electronics Engineers, Inc., 1990.
13. D. Grishenkov, C. Pecorari, T.B. Brismar, and G. Paradossi Characterization of acoustic properties of PVA-shelled ultrasound contrast agents: ultrasound-induced fracture (part II) Ultrasound Med. Biol. 35 2009 1139 1147
14. FDA, Information for Manufacturers Seeking Marketing Clearance of Diagnostic Ultrasound Systems and Transducers, US Food and Drug Administration, Rockville, MD, 1997.
15. E.P.W. Helps, and D.A. McDonald Observations on laminar flow in veins J. Physiol. 124 1954 631 639
16. R.M. Ross, K. Downey, J.M.B. Newman, S.M. Richards, M.G. Clark, and S. Rattigan Contrast-enhanced ultrasound measurement of microvascular perfusion relevant to nutrient and hormone delivery in skeletal muscle: a model study in vitro Microvasc. Res. 75 2008 323 329
17. Ultrasound Transducers, Technical Notes, Panametrics, Inc., NDT Division, 1999, p. 34.
18. D.M. Skyba, A.R. Jayaweera, N.C. Goodman, S. Ismail, G. Camarano, and S. Kaul Quantification of myocardial perfusion with myocardial contrast echocardiography during left atrial injection of contrast Circulation 90 1994 1513 1521
19. G. Tzvetkov, B. Graf, P. Fernandes, A. Fery, F. Cavalieri, G. Paradossi, and R. Fink Soft matter in situ characterization of gas-filled microballoons using soft X-ray microspectroscopy Soft Matter 4 2008 510 514
20. L. Hoff, P.C. Sontum, and J.M. Hovem Oscillations of polymeric microbubbles: effect of the encapsulating shell J. Acoust. Soc. Am. 107 2000 2272 2280
21. K. Wei Contrast echocardiography: fulfilling its promise ACC Curr. J. Rev. 14 2005 26 32
22. P. Marmottant, S. van der Meer, M. Emmer, M. Versluis, N. de Jong, S. Hilgenfeld, and D. Lohse A model for large amplitude oscillations of coated bubbles accounting for buckling and rupture J. Acoust. Soc. Am. 118 2005 3499 3505
23. K. Wei, M. Ragosta, J. Thorpe, M. Coggins, S. Moos, and S. Kaul Noninvasive quantification of coronary blood flow reserve in humans using myocardial contrast echocardiography Circulation 103 2001 2560 2565
24. T. Irvine, S. Wanitkun, J. Powers, T. Shiota, A. Kenny, and D.J. Sahn Acoustically stimulated transient power scattering explains enhanced detection of the very low velocities in myocardial capillaries by power Doppler imaging: an in vitro study J. Am. Soc. Echocardiogr. 12 1999 643 649
25. D. Duerschmied, P. Maletzki, G. Freund, M. Olschewski, J. Seufert, C. Bode, and C. Hehrlein Analysis of muscle microcirculation in advanced diabetes mellitus by contrast enhanced ultrasound Diabetes Res. Clin. Pr. 81 2008 88 92
26. J.R. Levick An Introduction to Cardiovascular Physiology fourth ed. 2003 Hodder Headline Group Arnold pp. 6-8
27. M. Krix, F. Kiessling, S. Vosseler, N. Farhan, M.M. Mueller, P. Bohlen, N.E. Fusenig, and S. Delorme Sensitive noninvasive monitoring of tumor perfusion during antiangiogenic therapy by intermittent bolus-contrast power Doppler sonography Cancer Res. 63 2003 8264 8270