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Volumn 6, Issue 11, 2010, Pages 2174-2191

Investigating dynamics of inhibitory and feedback loops in ERK signalling using power-law models

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN;

EID: 77957928119     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c0mb00018c     Document Type: Article
Times cited : (18)

References (58)
  • 1
    • 34248583886 scopus 로고    scopus 로고
    • MAP kinase signalling pathways in cancer
    • A. S. Dhillon S. Hagan O. Rath W. Kolch MAP kinase signalling pathways in cancer Oncogene 2007 26 3279 3290
    • (2007) Oncogene , vol.26 , pp. 3279-3290
    • Dhillon, A.S.1    Hagan, S.2    Rath, O.3    Kolch, W.4
  • 2
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • S. Yoon R. Seger The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions Growth Factors 2006 24 21 44
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 3
    • 27644575157 scopus 로고    scopus 로고
    • Coordinating ERK/MAPK signalling through scaffolds and inhibitors
    • W. Kolch Coordinating ERK/MAPK signalling through scaffolds and inhibitors Nat. Rev. Mol. Cell Biol. 2005 6 827 837
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 827-837
    • Kolch, W.1
  • 5
    • 41849102400 scopus 로고    scopus 로고
    • Raf kinase inhibitory protein: A signal transduction modulator and metastasis suppressor
    • A. E. Granovsky M. R. Rosner Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor Cell Res. 2008 18 452 457
    • (2008) Cell Res. , vol.18 , pp. 452-457
    • Granovsky, A.E.1    Rosner, M.R.2
  • 6
    • 0033539167 scopus 로고    scopus 로고
    • Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP
    • K. Yeung T. Seitz S. Li P. Janosch B. McFerran et al., Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP Nature 1999 401 6749 173 7
    • (1999) Nature , vol.401 , Issue.6749 , pp. 173-7
    • Yeung, K.1    Seitz, T.2    Li, S.3    Janosch, P.4    McFerran, B.5
  • 7
    • 27144473329 scopus 로고    scopus 로고
    • Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis
    • S. Hagan F. Al-Mulla E. Mallon K. Oien Ferrier et al., Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis Clin. Cancer Res. 2005 11 20 7392 7
    • (2005) Clin. Cancer Res. , vol.11 , Issue.20 , pp. 7392-7
    • Hagan, S.1    Al-Mulla, F.2    Mallon, E.3    Oien Ferrier, K.4
  • 8
    • 0034003003 scopus 로고    scopus 로고
    • Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein
    • K. Yeung P. Janosch B. McFerran D. W. Rose H. J. M. Mischak et al., Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein Mol. Cell. Biol. 2000 20 3079 85
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3079-85
    • Yeung, K.1    Janosch, P.2    McFerran, B.3    Rose, D.W.4    Mischak, H.J.M.5
  • 12
    • 59049094552 scopus 로고    scopus 로고
    • A system biology approach to understand functional activity of cell communication systems
    • J. Vera O. Wolkenhauer A system biology approach to understand functional activity of cell communication systems Methods Cell Biol. 2008 90 399 415
    • (2008) Methods Cell Biol. , vol.90 , pp. 399-415
    • Vera, J.1    Wolkenhauer, O.2
  • 13
    • 0033737840 scopus 로고    scopus 로고
    • Inferring qualitative relations in genetic networks and metabolic pathways
    • T. Akutsu S. Miyano S. Kuhara Inferring qualitative relations in genetic networks and metabolic pathways Bioinformatics 2000 16 8 727 734
    • (2000) Bioinformatics , vol.16 , Issue.8 , pp. 727-734
    • Akutsu, T.1    Miyano, S.2    Kuhara, S.3
  • 14
    • 0037461033 scopus 로고    scopus 로고
    • Dynamic modeling of genetic networks using genetic algorithm and S-system
    • S. Kikuchi D. Tominaga M. Arita K. Takahashi M. Tomita Dynamic modeling of genetic networks using genetic algorithm and S-system Bioinformatics 2003 19 5 643 650
    • (2003) Bioinformatics , vol.19 , Issue.5 , pp. 643-650
    • Kikuchi, S.1    Tominaga, D.2    Arita, M.3    Takahashi, K.4    Tomita, M.5
  • 16
    • 44049102421 scopus 로고    scopus 로고
    • A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway
    • J. Vera J. Bachmann A. C. Pfeifer V. Becker J. Hormiga et al., A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway BMC Syst. Biol. 2008 2 38
    • (2008) BMC Syst. Biol. , vol.2 , pp. 38
    • Vera, J.1    Bachmann, J.2    Pfeifer, A.C.3    Becker, V.4    Hormiga, J.5
  • 17
  • 18
    • 72949106670 scopus 로고    scopus 로고
    • Dynamical effects of epigenetic silencing of 14-3-3sigma expression
    • J. Vera J. Schultz S. Ibrahim Y. Raatz O. Wolkenhauer et al., Dynamical effects of epigenetic silencing of 14-3-3sigma expression Mol. BioSyst. 2010 6 1 264 63
    • (2010) Mol. BioSyst. , vol.6 , Issue.1 , pp. 264-63
    • Vera, J.1    Schultz, J.2    Ibrahim, S.3    Raatz, Y.4    Wolkenhauer, O.5
  • 19
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • H. D. Soule T. M. Maloney S. R. Wolman W. D. Peterson R. Brenz et al., Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10 Cancer Res. 1990 50 6075 6086
    • (1990) Cancer Res. , vol.50 , pp. 6075-6086
    • Soule, H.D.1    Maloney, T.M.2    Wolman, S.R.3    Peterson, W.D.4    Brenz, R.5
  • 20
    • 0014649230 scopus 로고
    • Biochemical systems analysis. I. Some mathematical properties of the rate law for the component enzymatic reactions
    • M. A. Savageau Biochemical systems analysis. I. Some mathematical properties of the rate law for the component enzymatic reactions J. Theor. Biol. 1969 25 3 365 9
    • (1969) J. Theor. Biol. , vol.25 , Issue.3 , pp. 365-9
    • Savageau, M.A.1
  • 21
    • 13444283465 scopus 로고    scopus 로고
    • Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae
    • F. Alvarez-Vasquez K. J. Sims L. A. Cowart Y. Okamoto E. O. Voit et al., Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae Nature 2005 433 7024 425 30
    • (2005) Nature , vol.433 , Issue.7024 , pp. 425-30
    • Alvarez-Vasquez, F.1    Sims, K.J.2    Cowart, L.A.3    Okamoto, Y.4    Voit, E.O.5
  • 22
    • 0038241770 scopus 로고    scopus 로고
    • Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli
    • M. R. Atkinson M. A. Savageau J. T. Myers A. J. Ninfa Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli Cell 2003 113 5 597 607
    • (2003) Cell , vol.113 , Issue.5 , pp. 597-607
    • Atkinson, M.R.1    Savageau, M.A.2    Myers, J.T.3    Ninfa, A.J.4
  • 23
    • 77949758449 scopus 로고    scopus 로고
    • Quantitative analysis of the dynamic signalling pathway involved in the cAMP mediated induction of l-carnitine biosynthesis in E. coli cultures
    • J. Hormiga C. González-Alcón A. Sevilla M. Cánovas N. V. Torres Quantitative analysis of the dynamic signalling pathway involved in the cAMP mediated induction of l-carnitine biosynthesis in E. coli cultures Mol. BioSyst. 2010 6 4 699 71
    • (2010) Mol. BioSyst. , vol.6 , Issue.4 , pp. 699-71
    • Hormiga, J.1    González-Alcón, C.2    Sevilla, A.3    Cánovas, M.4    Torres, N.V.5
  • 24
    • 62649153951 scopus 로고    scopus 로고
    • Role of inhibitory proteins as modulators of oscillations in NFB signalling
    • S. Nikolov J. Vera O. Rath W. Kolch O. Wolkenhauer Role of inhibitory proteins as modulators of oscillations in NFB signalling IET Syst. Biol. 2009 3 2 59 76
    • (2009) IET Syst. Biol. , vol.3 , Issue.2 , pp. 59-76
    • Nikolov, S.1    Vera, J.2    Rath, O.3    Kolch, W.4    Wolkenhauer, O.5
  • 25
    • 68749099674 scopus 로고    scopus 로고
    • A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis
    • X. Lai S. Nikolov O. Wolkenhauer J. Vera A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis Comput. Biol. Chem. 2009 33 4 312 24
    • (2009) Comput. Biol. Chem. , vol.33 , Issue.4 , pp. 312-24
    • Lai, X.1    Nikolov, S.2    Wolkenhauer, O.3    Vera, J.4
  • 26
    • 0033665572 scopus 로고    scopus 로고
    • Extending the method of mathematically controlled comparison to include numerical comparisons
    • R. Alves M. A. Savageau Extending the method of mathematically controlled comparison to include numerical comparisons Bioinformatics 2000 16 9 786 9
    • (2000) Bioinformatics , vol.16 , Issue.9 , pp. 786-9
    • Alves, R.1    Savageau, M.A.2
  • 27
    • 0037899231 scopus 로고    scopus 로고
    • Multicriteria optimization of biochemical systems by linear programming: Application to production of ethanol by Saccharomyces cerevisiae
    • J. Vera P. de Atauri M. Cascante N. V. Torres Multicriteria optimization of biochemical systems by linear programming: application to production of ethanol by Saccharomyces cerevisiae Biotechnol. Bioeng. 2003 83 3 335 43
    • (2003) Biotechnol. Bioeng. , vol.83 , Issue.3 , pp. 335-43
    • Vera, J.1    De Atauri, P.2    Cascante, M.3    Torres, N.V.4
  • 29
    • 33746736869 scopus 로고    scopus 로고
    • Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock
    • E. Vilaprinyo R. Alves A. Sorribas Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock BMC Bioinformatics 2006 7 184
    • (2006) BMC Bioinformatics , vol.7 , pp. 184
    • Vilaprinyo, E.1    Alves, R.2    Sorribas, A.3
  • 30
    • 20144387371 scopus 로고    scopus 로고
    • Inference of S-system models of genetic networks using a cooperative coevolutionary algorithm
    • S. Kimura K. Ide A. Kashihara M. Kano M. Hatakeyama et al., Inference of S-system models of genetic networks using a cooperative coevolutionary algorithm Bioinformatics 2004 21 7 1154 1163
    • (2004) Bioinformatics , vol.21 , Issue.7 , pp. 1154-1163
    • Kimura, S.1    Ide, K.2    Kashihara, A.3    Kano, M.4    Hatakeyama, M.5
  • 32
    • 20444478968 scopus 로고    scopus 로고
    • Computation and analysis of time-dependent sensitivities in Generalized Mass Action systems
    • J. H. Schwacke E. O. Voit Computation and analysis of time-dependent sensitivities in Generalized Mass Action systems J. Theor. Biol. 2005 236 1 21 38
    • (2005) J. Theor. Biol. , vol.236 , Issue.1 , pp. 21-38
    • Schwacke, J.H.1    Voit, E.O.2
  • 33
    • 34248179139 scopus 로고    scopus 로고
    • The potential for signal integration and processing in interacting MAP kinase cascades
    • J. H. Schwacke E. O. Voit The potential for signal integration and processing in interacting MAP kinase cascades J. Theor. Biol. 2007 246 4 604 620
    • (2007) J. Theor. Biol. , vol.246 , Issue.4 , pp. 604-620
    • Schwacke, J.H.1    Voit, E.O.2
  • 34
    • 33644524741 scopus 로고    scopus 로고
    • Cell-signalling dynamics in time and space
    • B. N. Kholodenko Cell-signalling dynamics in time and space Nat. Rev. Mol. Cell Biol. 2006 7 3 165 76
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , Issue.3 , pp. 165-76
    • Kholodenko, B.N.1
  • 36
    • 67649663892 scopus 로고    scopus 로고
    • Identification of neutral biochemical network models from time series data
    • M. Vilela S. Vinga M. A. Grivet Mattoso Maia et al., Identification of neutral biochemical network models from time series data BMC Syst. Biol. 2009 3 47
    • (2009) BMC Syst. Biol. , vol.3 , pp. 47
    • Vilela, M.1    Vinga, S.2    Grivet Mattoso Maia, M.A.3
  • 37
    • 65649102679 scopus 로고    scopus 로고
    • Recent developments in parameter estimation and structure identification of biochemical and genomic systems
    • Chou I-Chun E. O. Voit Recent developments in parameter estimation and structure identification of biochemical and genomic systems Math. Biosci. 2009 219 57 83
    • (2009) Math. Biosci. , vol.219 , pp. 57-83
    • Chou, I.1    Voit, E.O.2
  • 38
    • 77954190584 scopus 로고    scopus 로고
    • Parameter identifiability of power-law biochemical system models
    • 10.1016/j.jbiotec.2010.02.019, in press
    • S. Srinath R. Gunawan Parameter identifiability of power-law biochemical system models J. Biotechnol. 2010 10.1016/j.jbiotec.2010.02.019
    • (2010) J. Biotechnol.
    • Srinath, S.1    Gunawan, R.2
  • 39
    • 48749095711 scopus 로고    scopus 로고
    • Computational Procedures for Optimal Experimental Design in Biological Systems
    • E. Balsa-Canto A. A. Alonso J. R. Banga Computational Procedures for Optimal Experimental Design in Biological Systems IET Syst. Biol. 2008 2 4 163 172
    • (2008) IET Syst. Biol. , vol.2 , Issue.4 , pp. 163-172
    • Balsa-Canto, E.1    Alonso, A.A.2    Banga, J.R.3
  • 40
    • 58149232578 scopus 로고    scopus 로고
    • Parameter estimation and optimal experimental design
    • J. R. Banga E. Balsa-Canto Parameter estimation and optimal experimental design Essays Biochem. 2008 45 195 210
    • (2008) Essays Biochem. , vol.45 , pp. 195-210
    • Banga, J.R.1    Balsa-Canto, E.2
  • 41
    • 77949475400 scopus 로고    scopus 로고
    • An iterative identification procedure for dynamic modeling of biochemical networks
    • E. Balsa-Canto A. A. Alonso J. R. Banga An iterative identification procedure for dynamic modeling of biochemical networks BMC Syst. Biol. 2010 4 11
    • (2010) BMC Syst. Biol. , vol.4 , pp. 11
    • Balsa-Canto, E.1    Alonso, A.A.2    Banga, J.R.3
  • 42
    • 0032406131 scopus 로고    scopus 로고
    • Nonlinear optimization of biochemical pathways: Applications to metabolic engineering and parameter estimation
    • P. Mendes D. B. Kell Nonlinear optimization of biochemical pathways: Applications to metabolic engineering and parameter estimation Bioinformatics 1998 14 869 883
    • (1998) Bioinformatics , vol.14 , pp. 869-883
    • Mendes, P.1    Kell, D.B.2
  • 43
    • 0242574982 scopus 로고    scopus 로고
    • Parameter estimation in biochemical pathways: A comparison of global optimization methods
    • C. Moles P. Mendes J. Banga Parameter estimation in biochemical pathways: a comparison of global optimization methods Genome Res. 2003 13 2467 2474
    • (2003) Genome Res. , vol.13 , pp. 2467-2474
    • Moles, C.1    Mendes, P.2    Banga, J.3
  • 44
    • 33751423943 scopus 로고    scopus 로고
    • Novel Metaheuristic for Parameter Estimation in Nonlinear Dynamic Biological Systems
    • M. Rodriguez-Fernandez J. A. Egea J. R. Banga Novel Metaheuristic for Parameter Estimation in Nonlinear Dynamic Biological Systems BMC Bioinformatics 2006 7 483
    • (2006) BMC Bioinformatics , vol.7 , pp. 483
    • Rodriguez-Fernandez, M.1    Egea, J.A.2    Banga, J.R.3
  • 45
    • 17044395470 scopus 로고    scopus 로고
    • Reverse engineering of biochemical equations from time-course data by means of genetic programming
    • M. Sugimoto S. Kikuchi M. Tomita Reverse engineering of biochemical equations from time-course data by means of genetic programming BioSystems 2005 80 155 164
    • (2005) BioSystems , vol.80 , pp. 155-164
    • Sugimoto, M.1    Kikuchi, S.2    Tomita, M.3
  • 47
    • 41849104688 scopus 로고    scopus 로고
    • Hybrid optimization method with general switching strategy for parameter estimation
    • E. Balsa-Canto M. Peifer J. R. Banga et al., Hybrid optimization method with general switching strategy for parameter estimation BMC Syst. Biol. 2008 2 26
    • (2008) BMC Syst. Biol. , vol.2 , pp. 26
    • Balsa-Canto, E.1    Peifer, M.2    Banga, J.R.3
  • 49
    • 58549083142 scopus 로고    scopus 로고
    • Input-output behavior of ErbB signalling pathways as revealed by a mass action model trained against dynamic data
    • F. Catalanotti G. Reyes V. Jesenberger G. Galabova-Kovacs et al., Input-output behavior of ErbB signalling pathways as revealed by a mass action model trained against dynamic data Mol. Syst. Biol. 2009 5 239
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 239
    • Catalanotti, F.1    Reyes, G.2    Jesenberger, V.3    Galabova-Kovacs, G.4
  • 50
    • 84958662607 scopus 로고    scopus 로고
    • Mathematical Modelling of the Influence of RKIP on the ERK Signalling Pathway
    • G. Goos, J. Hartmanis and J. van Leeuwen, Springer Verlag, pp. 127-141
    • K. H. Cho, S. Y. Shin, H. W. Kim, O. Wolkenhauer and B. McFerran, et al., Mathematical Modelling of the Influence of RKIP on the ERK Signalling Pathway, in Computational Methods in Systems Biology, ed., G. Goos,,, J. Hartmanis, and, J. van Leeuwen,, Springer Verlag, 2003, pp. 127-141
    • (2003) Computational Methods in Systems Biology
    • Cho, K.H.1    Shin, S.Y.2    Kim, H.W.3    Wolkenhauer, O.4    McFerran, B.5
  • 51
    • 65249103982 scopus 로고    scopus 로고
    • Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway
    • S. Y. Shin O. Rath S. M. Choo F. Fee McFerran et al., Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway J. Cell Sci. 2009 122 425 435
    • (2009) J. Cell Sci. , vol.122 , pp. 425-435
    • Shin, S.Y.1    Rath, O.2    Choo, S.M.3    Fee McFerran, F.4
  • 52
    • 0021869852 scopus 로고
    • Sensitivity analysis of systems of differential and algebraic equations
    • J. R. Leis M. A. Kramer Sensitivity analysis of systems of differential and algebraic equations Comput. Chem. Eng. 1985 9 1 93 96
    • (1985) Comput. Chem. Eng. , vol.9 , Issue.1 , pp. 93-96
    • Leis, J.R.1    Kramer, M.A.2
  • 53
    • 0034019315 scopus 로고    scopus 로고
    • Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
    • B. Kholodenko Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades Eur. J. Biochem. 2000 267 1583 1588
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1583-1588
    • Kholodenko, B.1
  • 54
    • 0036212767 scopus 로고    scopus 로고
    • Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
    • B. Schoeberl C. Eichler-Jonsson E. D. Gilles G. Müller Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors Nat. Biotechnol. 2002 20 4 370 5
    • (2002) Nat. Biotechnol. , vol.20 , Issue.4 , pp. 370-5
    • Schoeberl, B.1    Eichler-Jonsson, C.2    Gilles, E.D.3    Müller, G.4
  • 55
    • 58549083142 scopus 로고    scopus 로고
    • Input-output behavior of ErbB signalling pathways as revealed by a mass action model trained against dynamic data
    • W. W. Chen B. Schoeberl P. J. Jasper M. Niepel U. B. Nielsen et al., Input-output behavior of ErbB signalling pathways as revealed by a mass action model trained against dynamic data Mol. Syst. Biol. 2009 5 239
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 239
    • Chen, W.W.1    Schoeberl, B.2    Jasper, P.J.3    Niepel, M.4    Nielsen, U.B.5
  • 56
    • 33847355217 scopus 로고    scopus 로고
    • Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
    • S. D. Santos P. J. Verveer P. I. Bastiaens Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate Nat. Cell Biol. 2007 9 3 324 30
    • (2007) Nat. Cell Biol. , vol.9 , Issue.3 , pp. 324-30
    • Santos, S.D.1    Verveer, P.J.2    Bastiaens, P.I.3
  • 57
    • 73849116154 scopus 로고    scopus 로고
    • Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions
    • M. Schilling T. Maiwald S. Hengl D. Winter C. Kreutz et al., Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions Mol. Syst. Biol. 2009 5 334
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 334
    • Schilling, M.1    Maiwald, T.2    Hengl, S.3    Winter, D.4    Kreutz, C.5
  • 58
    • 71449121678 scopus 로고    scopus 로고
    • Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor
    • H. Shankaran D. L. Ippolito W. B. Chrisler H. Resat N. Bollinger et al., Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor Mol. Syst. Biol. 2009 5 332
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 332
    • Shankaran, H.1    Ippolito, D.L.2    Chrisler, W.B.3    Resat, H.4    Bollinger, N.5


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