메뉴 건너뛰기




Volumn 5, Issue 8, 2010, Pages

Immunity against Neisseria meningitidis serogroup C in the Dutch population before and after introduction of the meningococcal C conjugate vaccine

Author keywords

[No Author keywords available]

Indexed keywords

MENINGOCOCCUS VACCINE; POLYSACCHARIDE; SEROGROUP C MENINGOCOCCAL CONJUGATE VACCINE; TETANUS TOXOID;

EID: 77957923744     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012144     Document Type: Article
Times cited : (64)

References (42)
  • 1
    • 33644840604 scopus 로고    scopus 로고
    • Protection from routine vaccination at the age of 14 months with meningococcal serogroup C conjugate vaccine in the Netherlands
    • de Greeff SC, de Melker HE, Spanjaard L, Schouls LM, van Derende A (2006) Protection from routine vaccination at the age of 14 months with meningococcal serogroup C conjugate vaccine in the Netherlands. Pediatr Infect Dis J 25: 79-80.
    • (2006) Pediatr Infect Dis J , vol.25 , pp. 79-80
    • de Greeff, S.C.1    de Melker, H.E.2    Spanjaard, L.3    Schouls, L.M.4    van Derende, A.5
  • 4
    • 3242768475 scopus 로고    scopus 로고
    • Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction
    • Trotter CL, Andrews NJ, Kaczmarski EB, Miller E, Ramsay ME (2004) Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction. Lancet 364: 365-367.
    • (2004) Lancet , vol.364 , pp. 365-367
    • Trotter, C.L.1    Andrews, N.J.2    Kaczmarski, E.B.3    Miller, E.4    Ramsay, M.E.5
  • 5
    • 20444437173 scopus 로고    scopus 로고
    • Impact and effectiveness of meningococcal C conjugate vaccine following its introduction in Spain
    • Larrauri A, Cano R, Garcia M, Mateo S (2005) Impact and effectiveness of meningococcal C conjugate vaccine following its introduction in Spain. Vaccine 23: 4097-4100.
    • (2005) Vaccine , vol.23 , pp. 4097-4100
    • Larrauri, A.1    Cano, R.2    Garcia, M.3    Mateo, S.4
  • 6
    • 33746653839 scopus 로고    scopus 로고
    • Introduction of pneumococcal conjugate vaccine to the UK childhood immunisation programme, and changes to the meningitis C and Hib schedules
    • Cameron C, Pebody R (2006) Introduction of pneumococcal conjugate vaccine to the UK childhood immunisation programme, and changes to the meningitis C and Hib schedules. Euro.Surveill 11: E060302.
    • (2006) Euro.Surveill , vol.11
    • Cameron, C.1    Pebody, R.2
  • 7
    • 0035169929 scopus 로고    scopus 로고
    • Ability of 3 different meningococcal C conjugate vaccines to induce immunologic memory after a single dose in UK toddlers
    • Richmond P, Borrow R, Goldblatt D, Findlow J, Martin S, et al. (2001) Ability of 3 different meningococcal C conjugate vaccines to induce immunologic memory after a single dose in UK toddlers. J Infect. Dis 183: 160-163.
    • (2001) J Infect. Dis , vol.183 , pp. 160-163
    • Richmond, P.1    Borrow, R.2    Goldblatt, D.3    Findlow, J.4    Martin, S.5
  • 8
    • 13844254496 scopus 로고    scopus 로고
    • Lack of serum bactericidal activity in preschool children two years after a single dose of serogroup C meningococcal polysaccharide-protein conjugate vaccine
    • Snape MD, Kelly DF, Green B, Moxon ER, Borrow R, et al. (2005) Lack of serum bactericidal activity in preschool children two years after a single dose of serogroup C meningococcal polysaccharide-protein conjugate vaccine. Pediatr.Infect.Dis J 24: 128-131.
    • (2005) Pediatr.Infect.Dis J , vol.24 , pp. 128-131
    • Snape, M.D.1    Kelly, D.F.2    Green, B.3    Moxon, E.R.4    Borrow, R.5
  • 9
    • 47149093375 scopus 로고    scopus 로고
    • Seroprotection against serogroup C meningococcal disease in adolescents in the United Kingdom: Observational study
    • Snape MD, Kelly DF, Lewis S, Banner C, Kibwana L, et al. (2008) Seroprotection against serogroup C meningococcal disease in adolescents in the United Kingdom: observational study. BMJ 7659: 1487-1491.
    • (2008) BMJ , vol.7659 , pp. 1487-1491
    • Snape, M.D.1    Kelly, D.F.2    Lewis, S.3    Banner, C.4    Kibwana, L.5
  • 10
    • 55849138735 scopus 로고    scopus 로고
    • Seroprevalence of antibodies against serogroup C meningococci in England in the postvaccination era
    • Trotter CL, Borrow R, Findlow J, Holland A, Frankland S (2008) Seroprevalence of antibodies against serogroup C meningococci in England in the postvaccination era. Clin Vaccine Immunol 15: 1694-1698.
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1694-1698
    • Trotter, C.L.1    Borrow, R.2    Findlow, J.3    Holland, A.4    Frankland, S.5
  • 11
    • 0035112040 scopus 로고    scopus 로고
    • Serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom: Reevaluation of correlates of protection
    • Borrow R, Andrews N, Goldblatt D, Miller E (2001) Serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom: reevaluation of correlates of protection. Infect Immun 69: 1568-1573.
    • (2001) Infect Immun , vol.69 , pp. 1568-1573
    • Borrow, R.1    Andrews, N.2    Goldblatt, D.3    Miller, E.4
  • 12
    • 14844282302 scopus 로고    scopus 로고
    • Meningococcal surrogates of protection--serum bactericidal antibody activity
    • Borrow R, Balmer P, Miller E (2005) Meningococcal surrogates of protection--serum bactericidal antibody activity. Vaccine 23: 2222-2227.
    • (2005) Vaccine , vol.23 , pp. 2222-2227
    • Borrow, R.1    Balmer, P.2    Miller, E.3
  • 13
    • 33845910109 scopus 로고    scopus 로고
    • Population-based seroprevalence of Neisseria meningitidis serogroup C capsular antibody before the introduction of conjugate vaccine, in Australia
    • Backhouse JL, Gidding HF, MacIntyre CR, McIntyre PB, Gilbert GL (2007) Population-based seroprevalence of Neisseria meningitidis serogroup C capsular antibody before the introduction of conjugate vaccine, in Australia. Vaccine 25: 1310-1315.
    • (2007) Vaccine , vol.25 , pp. 1310-1315
    • Backhouse, J.L.1    Gidding, H.F.2    Macintyre, C.R.3    McIntyre, P.B.4    Gilbert, G.L.5
  • 14
    • 34848918872 scopus 로고    scopus 로고
    • Age-specific seroprevalence of serogroup C meningococcal serum bactericidal antibody activity and serogroup A, C, W135 and Y-specific IgG concentrations in the Turkish population during 2005
    • Ceyhan M, Yildirim I, Balmer P, Riley C, Laher G, et al. (2007) Age-specific seroprevalence of serogroup C meningococcal serum bactericidal antibody activity and serogroup A, C, W135 and Y-specific IgG concentrations in the Turkish population during 2005. Vaccine 25: 7233-7237.
    • (2007) Vaccine , vol.25 , pp. 7233-7237
    • Ceyhan, M.1    Yildirim, I.2    Balmer, P.3    Riley, C.4    Laher, G.5
  • 15
    • 0032434734 scopus 로고    scopus 로고
    • Immunosurveillance and the evaluation of national immunization programmes: A population-based approach
    • de Melker HE, Conyn-van Spaendonck MA (1998) Immunosurveillance and the evaluation of national immunization programmes: a population-based approach. Epidemiol.Infect 121: 637-643.
    • (1998) Epidemiol.Infect , vol.121 , pp. 637-643
    • de Melker, H.E.1    Conyn-Van spaendonck, M.A.2
  • 16
  • 17
    • 61949282875 scopus 로고    scopus 로고
    • Simultaneous detection of Haemophilus influenzae type b polysaccharidespecific antibodies and Neisseria meningitidis serogroup A, C, Y, and W-135 polysaccharide-specific antibodies in a fluorescent-bead-based multiplex immunoassay
    • de Voer RM, Schepp RM, Versteegh FG, van der Klis FR, Berbers GA (2009) Simultaneous detection of Haemophilus influenzae type b polysaccharidespecific antibodies and Neisseria meningitidis serogroup A, C, Y, and W-135 polysaccharide-specific antibodies in a fluorescent-bead-based multiplex immunoassay. Clin.Vaccine Immunol 16: 433-436.
    • (2009) Clin.Vaccine Immunol , vol.16 , pp. 433-436
    • de Voer, R.M.1    Schepp, R.M.2    Versteegh, F.G.3    van der Klis, F.R.4    Berbers, G.A.5
  • 18
    • 43049167404 scopus 로고    scopus 로고
    • Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus
    • van Gageldonk PG, van Schaijk FG, van der Klis FR, Berbers GA (2008) Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus. J Immunol Methods 335: 79-89.
    • (2008) J Immunol Methods , vol.335 , pp. 79-89
    • van Gageldonk, P.G.1    van Schaijk, F.G.2    van der Klis, F.R.3    Berbers, G.A.4
  • 19
    • 0342891343 scopus 로고    scopus 로고
    • Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group
    • Maslanka SE, Gheesling LL, Libutti DE, Donaldson KB, Harakeh HS, et al. (1997) Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group. Clin Diagn Lab Immunol 4: 156-167.
    • (1997) Clin Diagn Lab Immunol , vol.4 , pp. 156-167
    • Maslanka, S.E.1    Gheesling, L.L.2    Libutti, D.E.3    Donaldson, K.B.4    Harakeh, H.S.5
  • 20
    • 17344361836 scopus 로고    scopus 로고
    • Antibody avidity as a surrogate marker of successful priming by Haemophilus influenzae type b conjugate vaccines following infant immunization
    • Goldblatt D, Vaz AR, Miller E (1998) Antibody avidity as a surrogate marker of successful priming by Haemophilus influenzae type b conjugate vaccines following infant immunization. J Infect Dis 177: 1112-1115.
    • (1998) J Infect Dis , vol.177 , pp. 1112-1115
    • Goldblatt, D.1    Vaz, A.R.2    Miller, E.3
  • 21
    • 0026451929 scopus 로고
    • Complement activation by polyclonal immunoglobulin G1 and G2 antibodies against Staphylococcus aureus, Haemophilus influenzae type b, and tetanus toxoid
    • Bredius RG, Driedijk PC, Schouten MF, Weening RS, Out TA (1992) Complement activation by polyclonal immunoglobulin G1 and G2 antibodies against Staphylococcus aureus, Haemophilus influenzae type b, and tetanus toxoid. Infect Immun 60: 4838-4847.
    • (1992) Infect Immun , vol.60 , pp. 4838-4847
    • Bredius, R.G.1    Driedijk, P.C.2    Schouten, M.F.3    Weening, R.S.4    Out, T.A.5
  • 22
    • 67649491062 scopus 로고    scopus 로고
    • Investigation of serum bactericidal activity in childhood and adolescence 3-6 years after vaccination with a single dose of serogroup C meningococcal conjugate vaccine
    • Sakou II, Tzanakaki G, Tsolia MN, Sioumala M, Barbouni A, et al. (2009) Investigation of serum bactericidal activity in childhood and adolescence 3-6 years after vaccination with a single dose of serogroup C meningococcal conjugate vaccine. Vaccine 33: 4408-4411.
    • (2009) Vaccine , vol.33 , pp. 4408-4411
    • Sakou, I.I.1    Tzanakaki, G.2    Tsolia, M.N.3    Sioumala, M.4    Barbouni, A.5
  • 23
    • 59649129826 scopus 로고    scopus 로고
    • Immunogenicity of a reduced schedule of meningococcal group C conjugate vaccine given concomitantly with the Prevenar and Pediacel vaccines in healthy infants in the United Kingdom
    • Southern J, Borrow R, Andrews N, Morris R, Waight P, et al. (2009) Immunogenicity of a reduced schedule of meningococcal group C conjugate vaccine given concomitantly with the Prevenar and Pediacel vaccines in healthy infants in the United Kingdom. Clin Vaccine Immunol 16: 194-199.
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 194-199
    • Southern, J.1    Borrow, R.2    Andrews, N.3    Morris, R.4    Waight, P.5
  • 24
    • 75949085277 scopus 로고    scopus 로고
    • A Randomized, Multicenter, Open-Label Clinical Trial to Assess the Immunogenicity of a Meningococcal C Vaccine Booster Dose Administered to Children Aged 14 to 18 Months
    • Díez-Domingo J, Planelles Cantarino MV, Baldó Torrentí JM, Sansano MI, Rosich AJ, et al. (2010) A Randomized, Multicenter, Open-Label Clinical Trial to Assess the Immunogenicity of a Meningococcal C Vaccine Booster Dose Administered to Children Aged 14 to 18 Months. Pediatr Infect Dis J 29: 148-152.
    • (2010) Pediatr Infect Dis J , vol.29 , pp. 148-152
    • Díez-Domingo, J.1    Cantarino, P.M.V.2    Torrentí, B.J.M.3    Sansano, M.I.4    Rosich, A.J.5
  • 25
    • 74549171099 scopus 로고    scopus 로고
    • Kinetics of antibody persistence following administration of a combination meningococcal serogroup C and haemophilus influenzae type b conjugate vaccine in healthy infants in the United Kingdom primed with a monovalent meningococcal serogroup C vaccine
    • Borrow R, Andrews N, Findlow H, Waight P, Southern J, et al. (2010) Kinetics of antibody persistence following administration of a combination meningococcal serogroup C and haemophilus influenzae type b conjugate vaccine in healthy infants in the United Kingdom primed with a monovalent meningococcal serogroup C vaccine. Clin Vaccine Immunol 17: 154-159.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 154-159
    • Borrow, R.1    Andrews, N.2    Findlow, H.3    Waight, P.4    Southern, J.5
  • 26
    • 0014531759 scopus 로고
    • Human immunity to the meningococcus. I. The role of humoral antibodies
    • Goldschneider I, Gotschlich EC, Artenstein MS (1969) Human immunity to the meningococcus. I. The role of humoral antibodies. J Exp.Med 129: 1307-1326.
    • (1969) J Exp.Med , vol.129 , pp. 1307-1326
    • Goldschneider, I.1    Gotschlich, E.C.2    Artenstein, M.S.3
  • 28
    • 0036893360 scopus 로고    scopus 로고
    • Development of interleukin-12-producing capacity throughout childhood
    • Upham JW, Lee PT, Holt BJ, Heaton T, Prescott SL, et al. (2002) Development of interleukin-12-producing capacity throughout childhood. Infect Immun 70: 6583-6588.
    • (2002) Infect Immun , vol.70 , pp. 6583-6588
    • Upham, J.W.1    Lee, P.T.2    Holt, B.J.3    Heaton, T.4    Prescott, S.L.5
  • 29
    • 29644445162 scopus 로고    scopus 로고
    • Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival
    • Pihlgren M, Friedli M, Tougne C, Rochat AF, Lambert PH, et al. (2006) Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival. J Immunol 176: 165-172.
    • (2006) J Immunol , vol.176 , pp. 165-172
    • Pihlgren, M.1    Friedli, M.2    Tougne, C.3    Rochat, A.F.4    Lambert, P.H.5
  • 30
    • 33748045136 scopus 로고    scopus 로고
    • Persisting immune responses indicating long-term protection after booster dose with meningococcal group B outer membrane vesicle vaccine
    • Feiring B, Fuglesang J, Oster P, Naess LM, Helland OS, et al. (2006) Persisting immune responses indicating long-term protection after booster dose with meningococcal group B outer membrane vesicle vaccine. Clin Vaccine Immunol 13: 790-796.
    • (2006) Clin Vaccine Immunol , vol.13 , pp. 790-796
    • Feiring, B.1    Fuglesang, J.2    Oster, P.3    Naess, L.M.4    Helland, O.S.5
  • 31
    • 77952004260 scopus 로고    scopus 로고
    • Updated postlicensure surveillance of the meningococcal C conjugate vaccine in England and Wales: Effectiveness, validation of serological correlates of protection, and modeling predictions of the duration of herd immunity
    • Campbell H, Andrews N, Borrow R, Trotter C, Miller E (2010) Updated postlicensure surveillance of the meningococcal C conjugate vaccine in England and Wales: effectiveness, validation of serological correlates of protection, and modeling predictions of the duration of herd immunity. Clin Vaccine Immunol 17: 840-847.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 840-847
    • Campbell, H.1    Andrews, N.2    Borrow, R.3    Trotter, C.4    Miller, E.5
  • 32
    • 42149195029 scopus 로고    scopus 로고
    • The magnitude of the antibody and memory B cell responses during priming with a protein polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response
    • Blanchard RG, Snape MD, Kelly DF, John T, Morant A (2008) The magnitude of the antibody and memory B cell responses during priming with a protein polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response. J Immunol 180: 2165-2173.
    • (2008) J Immunol , vol.180 , pp. 2165-2173
    • Blanchard, R.G.1    Snape, M.D.2    Kelly, D.F.3    John, T.4    Morant, A.5
  • 33
    • 66949123804 scopus 로고    scopus 로고
    • Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis
    • de Voer RM, van der Klis FR, Nooitgedagt JE, Versteegh FG, van Huisseling JC, et al. (2009) Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis. Clin Infect Dis 49: 58-64.
    • (2009) Clin Infect Dis , vol.49 , pp. 58-64
    • de Voer, R.M.1    van der Klis, F.R.2    Nooitgedagt, J.E.3    Versteegh, F.G.4    van Huisseling, J.C.5
  • 34
    • 0030070764 scopus 로고    scopus 로고
    • Meningococcal antibody titres in infants of women immunised with meningococcal polysaccharide vaccine during pregnancy
    • O'Dempsey TJ, McArdle T, Ceesay SJ, Secka O, Demba E, et al. (1996) Meningococcal antibody titres in infants of women immunised with meningococcal polysaccharide vaccine during pregnancy. Arch Dis Child Fetal Neonatal Ed 74: F43-F46.
    • (1996) Arch Dis Child Fetal Neonatal Ed , vol.74
    • O'Dempsey, T.J.1    McArdle, T.2    Ceesay, S.J.3    Secka, O.4    Demba, E.5
  • 35
    • 0014527763 scopus 로고
    • Human immunity to the meningococcus. II. Development of natural immunity
    • Goldschneider I, Gotschlich EC, Artenstein MS (1969) Human immunity to the meningococcus. II. Development of natural immunity. J Exp Med 129: 1327-1348.
    • (1969) J Exp Med , vol.129 , pp. 1327-1348
    • Goldschneider, I.1    Gotschlich, E.C.2    Artenstein, M.S.3
  • 36
    • 0037172392 scopus 로고    scopus 로고
    • Carriage of serogroup C meningococci 1 year after meningococcal C conjugate polysaccharide vaccination
    • Maiden MC, Stuart JM (2002) Carriage of serogroup C meningococci 1 year after meningococcal C conjugate polysaccharide vaccination. Lancet 359: 1829-1831.
    • (2002) Lancet , vol.359 , pp. 1829-1831
    • Maiden, M.C.1    Stuart, J.M.2
  • 37
    • 0015428454 scopus 로고
    • Enteric bacteria cross-reactive with Neisseria meningitidis groups A and C and Diplococcus pneumoniae types I and 3
    • Robbins JB, Myerowitz L, Whisnant JK, Argaman M, Schneerson R, et al. (1972) Enteric bacteria cross-reactive with Neisseria meningitidis groups A and C and Diplococcus pneumoniae types I and 3. Infect Immun 6: 651-656.
    • (1972) Infect Immun , vol.6 , pp. 651-656
    • Robbins, J.B.1    Myerowitz, L.2    Whisnant, J.K.3    Argaman, M.4    Schneerson, R.5
  • 38
    • 0015729812 scopus 로고
    • Polysaccharides of the genus Bacillus cross-reactive with the capsular polysaccharides of Diplococcus pneumoniae type 3, Haemophilus influenzae type b, and Neisseria meningitidis group A
    • Myerowitz RL, Gordon RE, Robbins JB (1973) Polysaccharides of the genus Bacillus cross-reactive with the capsular polysaccharides of Diplococcus pneumoniae type 3, Haemophilus influenzae type b, and Neisseria meningitidis group A. Infect Immun 8: 896-900.
    • (1973) Infect Immun , vol.8 , pp. 896-900
    • Myerowitz, R.L.1    Gordon, R.E.2    Robbins, J.B.3
  • 39
    • 0017153311 scopus 로고
    • Bacillus pumilus polysaccharide crossreactive with meningococcal group A polysaccharide
    • Vann WF, Liu TY, Robbins JB (1976) Bacillus pumilus polysaccharide crossreactive with meningococcal group A polysaccharide. Infect Immun 13: 1654-1662.
    • (1976) Infect Immun , vol.13 , pp. 1654-1662
    • Vann, W.F.1    Liu, T.Y.2    Robbins, J.B.3
  • 40
    • 33751555760 scopus 로고    scopus 로고
    • Serogroup C meningococcal glycoconjugate vaccine in adolescents: Persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization
    • Snape MD, Kelly DF, Salt P, Green S, Snowden C, et al. (2006) Serogroup C meningococcal glycoconjugate vaccine in adolescents: persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization. Clin Infect Dis 43: 1387-1394.
    • (2006) Clin Infect Dis , vol.43 , pp. 1387-1394
    • Snape, M.D.1    Kelly, D.F.2    Salt, P.3    Green, S.4    Snowden, C.5
  • 41
    • 70449095879 scopus 로고    scopus 로고
    • Kinetics of antibody responses after primary immunization with meningococcal serogroup C conjugate vaccine or secondary immunization with either conjugate or polysaccharide vaccine in adults
    • de Voer RM, van der Klis FR, Engels CW, Schepp RM, van de Kassteele J, et al. (2009) Kinetics of antibody responses after primary immunization with meningococcal serogroup C conjugate vaccine or secondary immunization with either conjugate or polysaccharide vaccine in adults. Vaccine 27: 6974-6982.
    • (2009) Vaccine , vol.27 , pp. 6974-6982
    • de Voer, R.M.1    van der Klis, F.R.2    Engels, C.W.3    Schepp, R.M.4    van de Kassteele, J.5
  • 42
    • 0033033037 scopus 로고    scopus 로고
    • Meningococcal serogroup C conjugate vaccine is immunogenic in infancy and primes for memory
    • Richmond P, Borrow R, Miller E, Clark S, Sadler F, et al. (1999) Meningococcal serogroup C conjugate vaccine is immunogenic in infancy and primes for memory. J Infect Dis 179: 1569-1572.
    • (1999) J Infect Dis , vol.179 , pp. 1569-1572
    • Richmond, P.1    Borrow, R.2    Miller, E.3    Clark, S.4    Sadler, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.