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Volumn 34, Issue 10, 2010, Pages 1554-1558

Knockdown of the Alström syndrome-associated gene Alms1 in 3T3-L1 preadipocytes impairs adipogenesis but has no effect on cell-autonomous insulin action

Author keywords

adipogenesis; Alms1; Alstr m syndrome; centrosome; diabetes; IR

Indexed keywords

INSULIN;

EID: 77957896245     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2010.92     Document Type: Article
Times cited : (27)

References (21)
  • 1
    • 1542510700 scopus 로고    scopus 로고
    • Acquired and inherited lipodystrophies
    • Garg A. Acquired and inherited lipodystrophies. N Engl J Med 2004; 350: 1220-1234.
    • (2004) N Engl J Med , vol.350 , pp. 1220-1234
    • Garg, A.1
  • 2
    • 58149485817 scopus 로고    scopus 로고
    • Human obesity as a heritable disorder of the central control of energy balance
    • O'Rahilly S, Farooqi IS. Human obesity as a heritable disorder of the central control of energy balance. Int J Obes (Lond) 2008; 32 (Suppl 7): S55-S61.
    • (2008) Int J Obes (Lond) , vol.32 , Issue.SUPPL. 7
    • O'Rahilly, S.1    Farooqi, I.S.2
  • 3
    • 54749114466 scopus 로고    scopus 로고
    • It's not how fat you are, it's what you do with it that counts
    • Virtue S, Vidal-Puig A. It's not how fat you are, it's what you do with it that counts. PLoS Biol 2008; 6: e237.
    • (2008) PLoS Biol , vol.6
    • Virtue, S.1    Vidal-Puig, A.2
  • 5
    • 33747724012 scopus 로고    scopus 로고
    • Syndromic obesity and diabetes: Changes in body composition with age and mutation analysis of ALMS1 in 12 United Kingdom kindreds with Alstrom syndrome
    • Minton JA, Owen KR, Ricketts CJ, Crabtree N, Shaikh G, Ehtisham S et al. Syndromic obesity and diabetes: changes in body composition with age and mutation analysis of ALMS1 in 12 United Kingdom kindreds with Alstrom syndrome. J Clin Endocrinol Metab 2006; 91: 3110-3116.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3110-3116
    • Minton, J.A.1    Owen, K.R.2    Ricketts, C.J.3    Crabtree, N.4    Shaikh, G.5    Ehtisham, S.6
  • 6
    • 0036578890 scopus 로고    scopus 로고
    • Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome
    • Collin GB, Marshall JD, Ikeda A, So WV, Russell-Eggitt I, Maffei P et al. Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome. Nat Genet 2002; 31: 74-78.
    • (2002) Nat Genet , vol.31 , pp. 74-78
    • Collin, G.B.1    Marshall, J.D.2    Ikeda, A.3    So, W.V.4    Russell-Eggitt, I.5    Maffei, P.6
  • 7
    • 18544391142 scopus 로고    scopus 로고
    • Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome
    • Hearn T, Renforth GL, Spalluto C, Hanley NA, Piper K, Brickwood S et al. Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome. Nat Genet 2002; 31: 79-83.
    • (2002) Nat Genet , vol.31 , pp. 79-83
    • Hearn, T.1    Renforth, G.L.2    Spalluto, C.3    Hanley, N.A.4    Piper, K.5    Brickwood, S.6
  • 8
    • 17844367633 scopus 로고    scopus 로고
    • Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes
    • Hearn T, Spalluto C, Phillips VJ, Renforth GL, Copin N, Hanley NA et al. Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. Diabetes 2005; 54: 1581-1587.
    • (2005) Diabetes , vol.54 , pp. 1581-1587
    • Hearn, T.1    Spalluto, C.2    Phillips, V.J.3    Renforth, G.L.4    Copin, N.5    Hanley, N.A.6
  • 10
    • 50949112676 scopus 로고    scopus 로고
    • The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation
    • Payne VA, Grimsey N, Tuthill A, Virtue S, Gray SL, Dalla Nora E et al. The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation. Diabetes 2008; 57: 2055-2060.
    • (2008) Diabetes , vol.57 , pp. 2055-2060
    • Payne, V.A.1    Grimsey, N.2    Tuthill, A.3    Virtue, S.4    Gray, S.L.5    Dalla Nora, E.6
  • 11
    • 0032723877 scopus 로고    scopus 로고
    • Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like rowth factor receptor in 3T3-L1 adipocytes
    • Urso B, Cope DL, Kalloo-Hosein HE, Hayward AC, Whitehead JP, O'Rahilly S et al. Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like rowth factor receptor in 3T3-L1 adipocytes. J Biol Chem 1999; 274: 30864-30873.
    • (1999) J Biol Chem , vol.274 , pp. 30864-30873
    • Urso, B.1    Cope, D.L.2    Kalloo-Hosein, H.E.3    Hayward, A.C.4    Whitehead, J.P.5    O'Rahilly, S.6
  • 12
    • 47649118883 scopus 로고    scopus 로고
    • Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity
    • Romano S, Milan G, Veronese C, Collin GB, Marshall JD, Centobene C et al. Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity. Int J Mol Med 2008; 21: 731-736.
    • (2008) Int J Mol Med , vol.21 , pp. 731-736
    • Romano, S.1    Milan, G.2    Veronese, C.3    Collin, G.B.4    Marshall, J.D.5    Centobene, C.6
  • 13
    • 0035853804 scopus 로고    scopus 로고
    • DNA synthesis and mitotic clonal expansion is not a required step for 3T3-L1 preadipocyte differentiation into adipocytes
    • Qiu Z, Wei Y, Chen N, Jiang M, Wu J, Liao K. DNA synthesis and mitotic clonal expansion is not a required step for 3T3-L1 preadipocyte differentiation into adipocytes. J Biol Chem 2001; 276: 11988-11995.
    • (2001) J Biol Chem , vol.276 , pp. 11988-11995
    • Qiu, Z.1    Wei, Y.2    Chen, N.3    Jiang, M.4    Wu, J.5    Liao, K.6
  • 14
    • 0037422569 scopus 로고    scopus 로고
    • Mitotic clonal expansion: A synchronous process required for adipogenesis
    • Tang QQ, Otto TC, Lane MD. Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci USA 2003; 100: 44-49.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 44-49
    • Tang, Q.Q.1    Otto, T.C.2    Lane, M.D.3
  • 15
    • 33746891890 scopus 로고    scopus 로고
    • The primary cilium as the cell's antenna: Signaling at a sensory organelle
    • Singla V, Reiter JF. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 2006; 313: 629-633.
    • (2006) Science , vol.313 , pp. 629-633
    • Singla, V.1    Reiter, J.F.2
  • 17
    • 33846507060 scopus 로고    scopus 로고
    • A role for Alstrom syndrome protein, alms1, in kidney cilio-genesis and cellular quiescence
    • Li G, Vega R, Nelms K, Gekakis N, Goodnow C, McNamara Pet al. A role for Alstrom syndrome protein, alms1, in kidney cilio-genesis and cellular quiescence. PLoS Genet 2007; 3: e8.
    • (2007) PLoS Genet , vol.3
    • Li, G.1    Vega, R.2    Nelms, K.3    Gekakis, N.4    Goodnow, C.5    Pet Al., M.6
  • 19
    • 44849116310 scopus 로고    scopus 로고
    • The perfect storm: Obesity adipocyte dysfunction, and metabolic consequences
    • de Ferranti S, Mozaffarian D. The perfect storm: obesity adipocyte dysfunction, and metabolic consequences. Clin Chem 2008; 54: 945-955.
    • (2008) Clin Chem , vol.54 , pp. 945-955
    • De Ferranti, S.1    Mozaffarian, D.2
  • 20
  • 21
    • 76149140090 scopus 로고    scopus 로고
    • Pericentrin in cellular function and disease
    • Delaval B, Doxsey SJ. Pericentrin in cellular function and disease. J Cell Biol 2010; 188: 181-190.
    • (2010) JCell Biol , vol.188 , pp. 181-190
    • Delaval, B.1    Doxsey, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.