Plasma concentration of malaria parasite-derived macrophage migration inhibitory factor in uncomplicated malaria patients correlates with parasitemia and disease severity

Clinical and Vaccine Immunology

Volumn 17, Issue 10, 2010, Pages 1524-1532

  Han, Cong ^a   Lin, Yahui ^a   Shan, Guangliang ^a   Zhang, Zaixing ^b   Sun, Xiaodong ^b   Wang, Zhensheng ^a   Wei, Chunyan ^a   Deng, Yan ^b   Zhang, Lianhui ^a   Bu, Lingyi ^a   Shao, Dingding ^a   Wang, Heng ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b Yunnan Institute of Parasitic Diseases   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; HLA A ANTIGEN; HLA B ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3B4; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANTIBODY RESPONSE; ARTICLE; BODY TEMPERATURE; CHILD; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALARIA; MALE; NUCLEOTIDE SEQUENCE; PARASITEMIA; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SCHOOL CHILD; SEQUENCE ANALYSIS;

EID: 77957873007     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00149-10     Document Type: Article

References (35)

1. Arévalo-Herrera, M., A. Z. Valencia, J. Vergara, A. Bonelo, K. Fleischhauer, J. M. Gonzalez, J. C. Restrepo, J. A. Lopez, D. Valmori, G. Corradin, and S. Herrera. 2002. Identification of HLA-A2 restricted CD8(+) T-lymphocyte responses to Plasmodium vivax circumsporozoite protein in individuals naturally exposed to malaria. Parasite Immunol. 24:161-169.
2. Augustijn, K. D., R. Kleemann, J. Thompson, T. Kooistra, C. E. Crawford, S. E. Reece, A. Pain, A. H. Siebum, C. J. Janse, and A. P. Waters. 2007. Functional characterization of the Plasmodium falciparum and P. berghei homologues of macrophage migration inhibitory factor. Infect. Immun. 75: 1116-1128.
3. Awandare, G. A., J. B. Hittner, P. G. Kremsner, D. O. Ochiel, C. C. Keller, J. B. Weinberg, I. A. Clark, and D. J. Perkins. 2006. Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria. Clin. Immunol. 119:219-225.
4. Awandare, G. A., Y. Ouma, C. Ouma, T. Were, R. Otieno, C. C. Keller, G. C. Davenport, J. B. Hittner, J. Vulule, R. Ferrell, J. M. Ong'echa, and D. J. Perkins. 2007. Role of monocyte-acquired hemozoin in suppression of macrophage migration inhibitory factor in children with severe malarial anemia. Infect. Immun. 75:201-210.
5. Calandra, T., and T. Roger. 2003. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat. Rev. Immunol. 3:791-800.
6. Chaisavaneeyakorn, S., N. Lucchi, C. Abramowsky, C. Othoro, S. C. Chaiyaroj, Y. P. Shi, B. L. Nahlen, D. S. Peterson, J. M. Moore, and V. Udhayakumar. 2005. Immunohistological characterization of macrophage migration inhibitory factor expression in Plasmodium falciparum-infected placentas. Infect. Immun. 73:3287-3293.
7. Chaisavaneeyakorn, S., J. M. Moore, C. Othoro, J. Otieno, S. C. Chaiyaroj, Y. P. Shi, B. L. Nahlen, A. A. Lal, and V. Udhayakumar. 2002. Immunity to placental malaria. IV. Placental malaria is associated with up-regulation of macrophage migration inhibitory factor in intervillous blood. J. Infect. Dis. 186:1371-1375.
8. Chaiyaroj, S. C., A. S. Rutta, K. Muenthaisong, P. Watkins, M. Na Ubol, and S. Looareesuwan. 2004. Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria. Acta Trop. 89:319-327.
9. Clark, I. A., M. M. Awburn, R. O. Whitten, C. G. Harper, N. G. Liomba, M. E. Molyneux, and T. E. Taylor. 2003. Tissue distribution of migration inhibitory factor and inducible nitric oxide synthase in falciparum malaria and sepsis in African children. Malar. J. 2:6.
10. Clark, I. A., and W. B. Cowden. 2003. The pathophysiology of falciparum malaria. Pharmacol. Ther. 99:221-260.
11. Cordery, D. V., U. Kishore, S. Kyes, M. J. Shafi, K. R. Watkins, T. N. Williams, K. Marsh, and B. C. Urban. 2007. Characterization of a Plasmodium falciparum macrophage-migration inhibitory factor homologue. J. Infect. Dis. 195:905-912.
12. Day, N. P., T. T. Hien, T. Schollaardt, P. P. Loc, L. V. Chuong, T. T. Chau, N. T. Mai, N. H. Phu, D. X. Sinh, N. J. White, and M. Ho. 1999. The prognostic and pathophysiologic role of pro- and antiinflammatory cytokines in severe malaria. J. Infect. Dis. 180:1288-1297.
13. De Mast, Q., F. C. Sweep, M. McCall, A. Geurts-Moespot, C. Hermsen, T. Calandra, M. G. Netea, R. W. Sauerwein, and A. J. van der Ven. 2008. A decrease of plasma macrophage migration inhibitory factor concentration is associated with lower numbers of circulating lymphocytes in experimental Plasmodium falciparum malaria. Parasite Immunol. 30:133-138.
14. Fernandes, A. A., L. J. Carvalho, G. M. Zanini, A. M. Ventura, J. M. Souza, P. M. Cotias, I. L. Silva-Filho, and C. T. Daniel-Ribeiro. 2008. Similar cytokine responses and degrees of anemia in patients with Plasmodium falciparum and Plasmodium vivax infections in the Brazilian Amazon region. Clin. Vaccine Immunol. 15:650-658.
15. González, J. M., K. Peter, F. Esposito, I. Nebie, J. M. Tiercy, A. Bonelo, M. Arevalo-Herrera, D. Valmori, P. Romero, S. Herrera, G. Corradin, and J. A. Lopez. 2000. HLA-A*0201 restricted CD8+ T-lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN-gamma ELISPOT. Parasite Immunol. 22:501-514.
16. Grau, G. E., T. E. Taylor, M. E. Molyneux, J. J. Wirima, P. Vassalli, M. Hommel, and P. H. Lambert. 1989. Tumor necrosis factor and disease severity in children with falciparum malaria. N. Engl. J. Med. 320:1586-1591.
17. Hill, A. V., C. E. Allsopp, D. Kwiatkowski, N. M. Anstey, P. Twumasi, P. A. Rowe, S. Bennett, D. Brewster, A. J. McMichael, and B. M. Greenwood. 1991. Common west African HLA antigens are associated with protection from severe malaria. Nature 352:595-600.
18. Kurtzhals, J. A., V. Adabayeri, B. Q. Goka, B. D. Akanmori, J. O. Oliver- Commey, F. K. Nkrumah, C. Behr, and L. Hviid. 1998. Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria. Lancet 351:1768-1772.
19. Kwiatkowski, D., A. V. Hill, I. Sambou, P. Twumasi, J. Castracane, K. R. Manogue, A. Cerami, D. R. Brewster, and B. M. Greenwood. 1990. TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 336:1201-1204.
20. Lyke, K. E., R. Burges, Y. Cissoko, L. Sangare, M. Dao, I. Diarra, A. Kone, R. Harley, C. V. Plowe, O. K. Doumbo, and M. B. Sztein. 2004. Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. Infect. Immun. 72:5630-5637.
21. Martiney, J. A., B. Sherry, C. N. Metz, M. Espinoza, A. S. Ferrer, T. Calandra, H. E. Broxmeyer, and R. Bucala. 2000. Macrophage migration inhibitory factor release by macrophages after ingestion of Plasmodium chabaudi-infected erythrocytes: possible role in the pathogenesis of malarial anemia. Infect. Immun. 68:2259-2267.
22. May, J., B. Lell, A. J. Luty, C. G. Meyer, and P. G. Kremsner. 2001. HLA-DQB1*0501-restricted Th1 type immune responses to Plasmodium falciparum liver stage antigen 1 protect against malaria anemia and reinfections. J. Infect. Dis. 183:168-172.
23. May, J., C. G. Meyer, J. F. Kun, B. Lell, D. Luckner, A. K. Dippmann, U. Bienzle, and P. G. Kremsner. 1999. HLA class II factors associated with Plasmodium falciparum merozoite surface antigen allele families. J. Infect. Dis. 179:1042-1045.
24. McDevitt, M. A., J. Xie, G. Shanmugasundaram, J. Griffith, A. Liu, C. McDonald, P. Thuma, V. R. Gordeuk, C. N. Metz, R. Mitchell, J. Keefer, J. David, L. Leng, and R. Bucala. 2006. A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. J. Exp. Med. 203:1185-1196.
25. Meyer-Siegler, K. L., K. A. Iczkowski, and P. L. Vera. 2005. Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer. BMC Cancer 5:73.
26. Satoskar, A. R., M. Bozza, M. Rodriguez Sosa, G. Lin, and J. R. David. 2001. Migration-inhibitory factor gene-deficient mice are susceptible to cutaneous Leishmania major infection. Infect. Immun. 69:906-911.
27. Seoh, J. Y., M. Khan, S. H. Park, H. K. Park, M. H. Shin, E. H. Ha, B. E. Lee, K. Yoo, H. S. Han, S. Oh, J. H. Wi, C. K. Hong, C. H. Oh, Y. A. Kim, and J. W. Park. 2003. Serum cytokine profiles in patients with Plasmodium vivax malaria: a comparison between those who presented with and without hyperpyrexia. Am. J. Trop. Med. Hyg. 68:102-106.
28. Shaffer, N., G. E. Grau, K. Hedberg, F. Davachi, B. Lyamba, A. W. High-tower, J. G. Breman, and N. D. Phuc. 1991. Tumor necrosis factor and severe malaria. J. Infect. Dis. 163:96-101.
29. Shankarkumar, U., J. P. Devaraj, K. Ghosh, D. Karnad, K. Anand, and D. Mohanty. 2002. HLA associations in P. falciparum malaria patients from Mumbai, western India. Indian J. Malariol. 39:76-82.
30. Shao, D., Z. Han, Y. Lin, L. Zhang, X. Zhong, M. Feng, Y. Guo, and H. Wang. 2008. Detection of Plasmodium falciparum derived macrophage migration inhibitory factor homologue in the sera of malaria patients. Acta Tropica 106:9-15.
31. Shao, D., X. Zhong, Y. F. Zhou, Z. Han, Y. Lin, Z. Wang, L. Bu, L. Zhang, X. D. Su, and H. Wang. Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host. Mol. Immunol. 47:726-737.
32. Stavitsky, A. B., C. Metz, S. Liu, J. Xianli, and R. Bucala. 2003. Blockade of macrophage migration inhibitory factor (MIF) in Schistosoma japonicum-infected mice results in an increased adult worm burden and reduced fecundity. Parasite Immunol. 25:369-374.
33. Wang, Z., D. Shao, X. Zhong, C. Han, P. Cai, and H. Wang. 2009. Epitope mapping of monoclonal antibody 1B9 against plasmodium falciparum-derived macrophage migration inhibitory factor. Immunol. Investig. 38:422-433.
34. World Health Organization. 2000. Severe falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 94(Suppl. 1):S1-S90.
35. Zeyrek, F. Y., M. A. Kurcer, D. Zeyrek, and Z. Simsek. 2006. Parasite density and serum cytokine levels in Plasmodium vivax malaria in Turkey. Parasite Immunol. 28:201-207.