A crossover intervention trial evaluating the efficacy of a chlorhexidine-impregnated sponge in reducing catheter-related bloodstream infections among patients undergoing hemodialysis

Infection Control and Hospital Epidemiology

Volumn 31, Issue 11, 2010, Pages 1118-1123

  Camins, Bernard C ^a   Richmond, Amy M ^a,b   Dyer, Kathrin L ^a,d   Zimmerman, Heather N ^a,c   Coyne, Daniel W ^a   Rothstein, Marcos ^a   Fraser, Victoria J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BARNES JEWISH HOSPITAL   (United States)

^c MONTANA DEPARTMENT OF PUBLIC HEALTH AND HUMAN SERVICES   (United States)

^d Fulton County Health Department   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORHEXIDINE;

ADULT; AGED; ARTICLE; BLOODSTREAM INFECTION; CATHETER INFECTION; CENTRAL VENOUS CATHETER; DERMATITIS; FEMALE; HEMODIALYSIS; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; RISK FACTOR;

ADULT; AGED; AGED, 80 AND OVER; CATHETER-RELATED INFECTIONS; CHLORHEXIDINE; CROSS-OVER STUDIES; DISINFECTANTS; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RENAL DIALYSIS; SURGICAL SPONGES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77957864176     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/657075     Document Type: Article

References (19)

1. Causes of death. USRDS. United States renal data system. Am J Kidney Dis 1997;30(2 Suppl 1):S107-S17.
2. Mailloux LU, Bellucci AG,Wilkes BM, et al. Mortality in dialysis patients: analysis of the causes of death. Am J Kidney Dis 1991;18(3):326-335.
3. Taylor G, Gravel D, Johnston L, Embil J, Holton D, Paton S. Prospective surveillance for primary bloodstream infections occurring in Canadian hemodialysis units. Infect Control Hosp Epidemiol 2002;23(12):716-720.
4. Saeed Abdulrahman I, Al-Mueilo SH, Bokhary HA, Ladipo GOA, Al-Rubaish A. A prospective study of hemodialysis access-related bacterial infections. J Infect Chemother 2002;8(3):242-246.
5. Stevenson KB, Adcox MJ, Mallea MC, Narasimhan N, Wagnild JP. Standardized surveillance of hemodialysis vascular access infections: 18-month experience at an outpatient, multifacility hemodialysis center. Infect Control Hosp Epidemiol 2000;21(3):200-203.
6. Maki DG, Cobb L, Garman JK, Shapiro JM, Ringer M, Helgerson RB. An attachable silver-impregnated cuff for prevention of infection with central venous catheters: a prospective randomized multicenter trial. Am J Med 1988;85(3):307-314.
7. Levin A, Mason AJ, Jindal KK, Fong IW, Goldstein MB. Prevention of hemodialysis subclavian vein catheter infections by topical povidoneiodine. Kidney Int 1991;40(5):934-938.
8. Shapiro JM, Bond EL, Garman JK. Use of a chlorhexidine dressing to reduce microbial colonization of epidural catheters. Anesthesiology 1990;73(4):625-631.
9. Garland JS, Alex CP, Mueller CD, et al. A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates. Pediatrics 2001;107(6):1431-1436.
10. Chambers ST, Sanders J, Patton WN, et al. Reduction of exit-site infections of tunnelled intravascular catheters among neutropenic patients by sustained-release chlorhexidine dressings: results from a prospective randomized controlled trial. J Hosp Infect 2005;61(1):53-61.
11. Timsit JF, Schwebel C, Bouadma L, et al. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. JAMA 2009;301(12):1231-1241.
12. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16(3):128-140.
13. Lok CE, Stanley KE, Hux JE, Richardson R, Tobe SW, Conly J. Hemodialysis infection prevention with polysporin ointment. J Am Soc Nephrol 2003;14(1):169-179.
14. Johnson DW, MacGinley R, Kay TD, et al. A randomized controlled trial of topical exit site mupirocin application in patients with tunnelled, cuffed haemodialysis catheters. Nephrol Dial Transplant 2002;17(10):1802-1807.
15. Johnson DW, van EC, Mudge DW, et al. Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients. J Am Soc Nephrol 2005;16(5):1456-1462.
16. Oliver MJ, Rothwell DM, Fung K, Hux JE, Lok CE. Late creation of vascular access for hemodialysis and increased risk of sepsis. J Am Soc Nephrol 2004;15(7):1936-1942.
17. Abbott KC, Agodoa LY. Etiology of bacterial septicemia in chronic dialysis patients in the United States. Clin Nephrol 2001;56(2):124-131.
18. Powe NR, Jaar B, Furth SL, Hermann J, Briggs W. Septicemia in dialysis patients: incidence, risk factors, and prognosis. Kidney Int 1999;55(3):1081-1090.
19. Jaar BG, Hermann JA, Furth SL, Briggs W, Powe NR. Septicemia in diabetic hemodialysis patients: comparison of incidence, risk factors, and mortality with nondiabetic hemodialysis patients. Am J Kidney Dis 2000;35(2):282-292.