Hormone replacement therapy among postmenopausal women presenting with acute myocardial infarction: Insights from the GUSTO-III trial

American Heart Journal

Volumn 160, Issue 4, 2010, Pages 678-684

  Tackett, Andrea H ^a   Bailey, Alison L ^a   Foody, Joanne Micale ^b   Miller, Julie M ^c   Apperson Hansen, Carolyn ^d   Ohman, E Magnus ^e   Hochman, Judith S ^f   Karnash, Sharon L ^e   Califf, Robert M ^e   Topol, Eric J ^g   Moliterno, David J ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^g SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; ANTICOAGULANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ESTROGEN; HEPARIN; RETEPLASE;

ACUTE HEART INFARCTION; AGE; ARTICLE; ASYSTOLE; BLEEDING; CARDIOGENIC SHOCK; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CORONARY ARTERY RECANALIZATION; DIABETES MELLITUS; DISEASE ASSOCIATION; EMBOLISM; FEMALE; HORMONE SUBSTITUTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; HYPOTENSION; LUNG EDEMA; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MORTALITY; POSTMENOPAUSE; PRIORITY JOURNAL; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STROKE; THORAX PAIN; TREATMENT OUTCOME; UNITED STATES; AGED; COMPARATIVE STUDY; ELECTROCARDIOGRAPHY; EPIDEMIOLOGY; FOLLOW UP; MIDDLE AGED; MYOCARDIAL INFARCTION; PHASE 3 CLINICAL TRIAL; PROCEDURES; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE; TRENDS;

AGED; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HORMONE REPLACEMENT THERAPY; HUMANS; MIDDLE AGED; MYOCARDIAL INFARCTION; POSTMENOPAUSE; PROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME; UNITED STATES;

EID: 77957854061     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2010.06.030     Document Type: Article

References (63)

1. Lloyd-Jones D., Adams R., and Carnethon M. Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation 119 2009 e21 e181
2. Jneid H., Fonarow G.C., and Cannon C.P. Sex differences in medical care and early death after acute myocardial infarction Circulation 118 2008 2803 2810
3. Ayanian J.Z., and Epstein A.M. Attitudes about treatment of coronary heart disease among women and men presenting for exercise testing J Gen Intern Med 12 1997 311 314
4. Hochman J.S., Tamis J.E., and Thompson T.D. Sex, clinical presentation, and outcome in patients with acute coronary syndromes. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes IIb Investigators N Engl J Med 341 1999 226 232
5. Vaccarino V., Horwitz R.I., and Meehan T.P. Sex differences in mortality after myocardial infarction: evidence for a sex-age interaction Arch Intern Med 158 1998 2054 2062
6. Bearden D., Allman R., and McDonald R. Age, race, and gender variation in the utilization of coronary artery bypass surgery and angioplasty in SHEP. SHEP Cooperative Research Group. Systolic Hypertension in the Elderly Program J Am Geriatr Soc 42 1994 1143 1149
7. Beery T.A. Gender bias in the diagnosis and treatment of coronary artery disease Heart Lung 24 1995 427 435
8. Bergelson B.A., and Tommaso C.L. Gender differences in percutaneous interventional therapy of coronary artery disease Cathet Cardiovasc Diagn 37 1996 1 4
9. Lauer M.S., Pashkow F.J., and Snader C.E. Gender and referral for coronary angiography after treadmill thallium testing Am J Cardiol 78 1996 278 283
10. Wenger N.K. Coronary heart disease in women: gender differences in diagnostic evaluation J Am Med Womens Assoc 49 1994 181 5,197
11. Krumholz H.M., Douglas P.S., and Lauer M.S. Selection of patients for coronary angiography and coronary revascularization early after myocardial infarction: is there evidence for a gender bias? Ann Intern Med 116 1992 785 790
12. Kannel W.B., and Vokonas P.S. Demographics of the prevalence, incidence, and management of coronary heart disease in the elderly and in women Ann Epidemiol 2 1992 5 14
13. Iezzoni L.I., Ash A.S., and Shwartz M. Differences in procedure use, in-hospital mortality, and illness severity by gender for acute myocardial infarction patients: are answers affected by data source and severity measure? Med Care 35 1997 158 171
14. Halvorsen S., Eritsland J., and Abdelnoor M. Gender differences in management and outcome of acute myocardial infarctions treated in 2006-2007 Cardiology 114 2009 83 88
15. Chan M.Y., Sun J.L., and Newby L.K. Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction Circulation 119 2009 3110 3117
16. Akhter N., Milford-Beland S., and Roe M.T. Gender differences among patients with acute coronary syndromes undergoing percutaneous coronary intervention in the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR) Am Heart J 157 2009 141 148
17. Lansky A.J., Mehran R., and Cristea E. Impact of gender and antithrombin strategy on early and late clinical outcomes in patients with non-ST-elevation acute coronary syndromes (from the ACUITY trial) Am J Cardiol 103 2009 1196 1203
18. Grady D., Rubin S.M., and Petitti D.B. Hormone therapy to prevent disease and prolong life in postmenopausal women Ann Intern Med 117 1992 1016 1037
19. Meilahn E.N. Hemostatic factors and risk of cardiovascular disease in women. An overview Arch Pathol Lab Med 116 1992 1313 1317
20. Barrett-Connor E., Wingard D.L., and Criqui M.H. Postmenopausal estrogen use and heart disease risk factors in the 1980s. Rancho Bernardo, Calif, revisited JAMA 261 1989 2095 2100
21. Kannel W.B. Metabolic risk factors for coronary heart disease in women: perspective from the Framingham Study Am Heart J 114 1987 413 419
22. Chetkowski R.J., Meldrum D.R., and Steingold K.A. Biologic effects of transdermal estradiol N Engl J Med 314 1986 1615 1620
23. Scarabin P.Y., Plu-Bureau G., and Bara L. Haemostatic variables and menopausal status: influence of hormone replacement therapy Thromb Haemost 70 1993 584 587
24. Vlajinac H., Ilic M., and Marinkovic J. Cardiovascular risk factors and prevalence of coronary heart disease in type 2 (non-insulin-dependent) diabetes Eur J Epidemiol 8 1992 783 788
25. Vassilopoulou-Sellin R., and Zolinski C. Estrogen replacement therapy in women with breast cancer: a survey of patient attitudes Am J Med Sci 304 1992 145 149
26. Wilson P.W., Garrison R.J., and Castelli W.P. Postmenopausal estrogen use, cigarette smoking, and cardiovascular morbidity in women over 50. The Framingham Study N Engl J Med 313 1985 1038 1043
27. Castelli W.P. Epidemiology of coronary heart disease: the Framingham study Am J Med 76 1984 4 12
28. Cummings S.R. Evaluating the benefits and risks of postmenopausal hormone therapy Am J Med 91 1991 14S 18S
29. Eaker E.D., Packard B., and Thom T.J. Epidemiology and risk factors for coronary heart disease in women Cardiovasc Clin 19 1989 129 145
30. Stampfer M.J., Colditz G.A., and Willett W.C. Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study N Engl J Med 325 1991 756 762
31. Herrington D.M., Fong J., and Sempos C.T. Comparison of the Heart and Estrogen/Progestin Replacement Study (HERS) cohort with women with coronary disease from the National Health and Nutrition Examination Survey III (NHANES III) Am Heart J 136 1998 115 124
32. Haffner S.M., Lehto S., and Rönnemaa T. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction N Engl J Med 339 1998 229 234
33. Carey V.J., Walters E.E., and Colditz G.A. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study Am J Epidemiol 145 1997 614 619
34. Manson J.E. Postmenopausal hormone therapy and atherosclerotic disease Am Heart J 128 6 Pt 2 1994 1337 1343
35. Kritz-Silverstein D., and Barrett-Connor E. Long-term postmenopausal hormone use, obesity, and fat distribution in older women JAMA 275 1996 46 49
36. Manolio T.A., Furberg C.D., and Shemanski L. Associations of postmenopausal estrogen use with cardiovascular disease and its risk factors in older women. The CHS Collaborative Research Group Circulation 88 5 Pt 1 1993 2163 2171
37. Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study Group Control Clin Trials 19 1998 61 109
38. Hsia J., Langer R.D., and Manson J.E. Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative Arch Intern Med 166 2006 357 365 (Pubitemid 43244325)
39. Vickers M.R., MacLennan A.H., and Lawton B. Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): a randomised controlled trial of hormone replacement therapy in postmenopausal women BMJ 335 2007 239
40. Hulley S., Grady D., and Bush T. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group JAMA 280 1998 605 613
41. Grady D., Herrington D., and Bittner V. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II) JAMA 288 2002 49 57 (Pubitemid 34705518)
42. Clarke S.C., Kelleher J., and Lloyd-Jones H. A study of hormone replacement therapy in postmenopausal women with ischaemic heart disease: the Papworth HRT atherosclerosis study BJOG 109 2002 1056 1062
43. Cherry N., Gilmour K., and Hannaford P. Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial Lancet 360 2002 2001 2008
44. Shlipak M.G., Angeja B.G., and Go A.S. Hormone therapy and in-hospital survival after myocardial infarction in postmenopausal women Circulation 104 2001 2300 2304
45. Parsons E., Newby L.K., and Bhapkar M.V. Postmenopausal hormone use in women with acute coronary syndromes J Womens Health (Larchmt) 13 2004 863 871
46. Alexander K.P., Newby L.K., and Hellkamp A.S. Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up J Am Coll Cardiol 38 2001 1 7
47. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO III) Investigators. A comparison of reteplase with alteplase for acute myocardial infarction N Engl J Med 337 1997 1118 1123
48. Lee K.L., Woodlief L.H., and Topol E.J. Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators Circulation 91 1995 1659 1668
49. Grady D., Wenger N.K., and Herrington D. Postmenopausal hormone therapy increases risk for venous thromboembolic disease. The Heart and Estrogen/Progestin Replacement Study Ann Intern Med 132 2000 689 696
50. Mautner S.L., Lin F., and Mautner G.C. Comparison in women versus men of composition of atherosclerotic plaques in native coronary arteries and in saphenous veins used as aortocoronary conduits J Am Coll Cardiol 21 1993 1312 1318
51. Williams J.K., Adams M.R., and Klopfenstein H.S. Estrogen modulates responses of atherosclerotic coronary arteries Circulation 81 1990 1680 1687
52. Williams J.K., Adams M.R., and Herrington D.M. Short-term administration of estrogen and vascular responses of atherosclerotic coronary arteries J Am Coll Cardiol 20 1992 452 457
53. Stevenson J.C., Crook D., and Godsland I.F. Influence of age and menopause on serum lipids and lipoproteins in healthy women Atherosclerosis 98 1993 83 90
54. Herrington D.M., Reboussin D.M., and Klein K.P. The estrogen replacement and atherosclerosis (ERA) study: study design and baseline characteristics of the cohort Control Clin Trials 21 2000 257 285
55. Barrett-Connor E., and Miller V. Estrogens, lipids, and heart disease Clin Geriatr Med 9 1993 57 67
56. Knopp R.H., Zhu X., and Bonet B. Effects of estrogens on lipoprotein metabolism and cardiovascular disease in women Atherosclerosis 110 Suppl 1994 S83 S91
57. Barrett-Connor E. Hormones and heart disease in women: the timing hypothesis Am J Epidemiol 166 2007 506 510
58. Rossouw J.E., Prentice R.L., and Manson J.E. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause JAMA 297 2007 1465 1477
59. Manson J.E., Allison M.A., and Rossouw J.E. Estrogen therapy and coronary-artery calcification N Engl J Med 356 2007 2591 2602
60. Hodis H. Early versus late intervention trial with estrogen Retrieved March 8, 2010, from the ClinicalTrials.gov Web site: http://clinicaltrials.gov/ show/NCT00114517
61. Harman S.M. KEEPS: The Kronos Early Estrogen Prevention Study Climacteric 8 2005 3 12
62. Kannel W.B., and Wilson P.W. Risk factors that attenuate the female coronary disease advantage Arch Intern Med 155 1995 57 61
63. American College of Obstetricians and Gynecologists Committee on Gynecologic Practice. ACOG Committee Opinion No. 420, November 2008: hormone therapy and heart disease Obstet Gynecol 112 2008 1189 1192