Synthesis and in vitro antiproliferative activity of 5-alkyl-12(H)-quino[3, 4-b] [1,4]benzothiazinium salts

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 4733-4739

  Zięba, Andrzej ^a   Sochanik, Aleksander ^b   Szurko, Agnieszka ^b,c   Rams, Marzena ^c   Mrozek, Anna ^c   Cmoch, Piotr ^d  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b INSTITUTE OF ONCOLOGY   (Poland)

^c UNIVERSITY OF SILESIA   (Poland)

^d INSTITUTE OF ORGANIC CHEMISTRY   (Poland)

Author keywords

Antiproliferative activity; Aromatic nucleophilic substitution; Azaphenothiazine; Doxorubicin; Phenothiazine

Indexed keywords

1 METHYL 4 (2 AMINOPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (2 HYDROXYPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (3 AMINOPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (3 HYDROXYPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (4 AMINOPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (4 BROMOPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (4 FLUOROPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 1 METHYL 4 (4 HYDROXYPHENYLAMINO)QUINOLINIUM 3 THIOLATE; 10 AMINO 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; 10 HYDROXY 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; 11 AMINO 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; 11 HYDROXY 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; 5 BUTHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM BROMIDE; 5 DECYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM BROMIDE; 9 AMINO 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; 9 BROMO 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM; 9 FLUORO 12(H)QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; 9 HYDROXY 5 METHYL 12(H) QUINO[3,4 B][1,4]BENZOTHIAZINIUM CHLORIDE; ANTINEOPLASTIC AGENT; DOXORUBICIN; PHENOTHIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; ATOM; CANCER CELL; CONCENTRATION (PARAMETERS); CYCLIZATION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

EID: 77957851523     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.07.035     Document Type: Article

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