-
1
-
-
33644550641
-
Pulmonary arterial hypertension
-
Rubin LJ. Pulmonary arterial hypertension. Proc Am Thorac Soc 2006; 3: 111-115.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 111-115
-
-
Rubin, L.J.1
-
2
-
-
40949145735
-
Update in pulmonary arterial hypertension 2007
-
Humbert M. Update in pulmonary arterial hypertension 2007. Am J Respir Crit Care Med 2008; 177: 574-579.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 574-579
-
-
Humbert, M.1
-
3
-
-
66549127501
-
ACCF/AHA 2009 expert consensus document on pulmonary hypertension: A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association
-
McLaughlin VV, Archer SL, Badesch DB, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation 2009; 119: 2250-2294.
-
(2009)
Circulation
, vol.119
, pp. 2250-2294
-
-
McLaughlin, V.V.1
Archer, S.L.2
Badesch, D.B.3
-
4
-
-
70349634397
-
Guidelines for the diagnosis and treatment of pulmonary hypertension
-
Galie N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2009; 34: 1219-1263.
-
(2009)
Eur Respir J
, vol.34
, pp. 1219-1263
-
-
Galie, N.1
Hoeper, M.M.2
Humbert, M.3
-
5
-
-
4644290657
-
Treatment of pulmonary arterial hypertension
-
Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004; 351: 1425-1436.
-
(2004)
N Engl J Med
, vol.351
, pp. 1425-1436
-
-
Humbert, M.1
Sitbon, O.2
Simonneau, G.3
-
6
-
-
33646763902
-
Rho kinases in cardiovascular physiology and pathophysiology
-
Loirand G, Guerin P, Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ Res 2006; 98: 322-334.
-
(2006)
Circ Res
, vol.98
, pp. 322-334
-
-
Loirand, G.1
Guerin, P.2
Pacaud, P.3
-
7
-
-
4544388803
-
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase
-
Fagan KA, Oka M, Bauer NR, et al. Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol 2004; 287: L656-L664.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Fagan, K.A.1
Oka, M.2
Bauer, N.R.3
-
8
-
-
10744222390
-
Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats
-
Abe K, Shimokawa H, Morikawa K, et al. Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats. Circ Res 2004; 94: 385-393.
-
(2004)
Circ Res
, vol.94
, pp. 385-393
-
-
Abe, K.1
Shimokawa, H.2
Morikawa, K.3
-
9
-
-
4544244944
-
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats
-
Nagaoka T, Morio Y, Casanova N, et al. Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 2004; 287: L665-L672.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Nagaoka, T.1
Morio, Y.2
Casanova, N.3
-
10
-
-
15944403568
-
Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension
-
Nagaoka T, Fagan KA, Gebb SA, et al. Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. Am J Respir Crit Care Med 2005; 171: 494-499.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 494-499
-
-
Nagaoka, T.1
Fagan, K.A.2
Gebb, S.A.3
-
11
-
-
28444461454
-
Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension
-
Guilluy C, Sauzeau V, Rolli-Derkinderen M, et al. Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension. Br J Pharmacol 2005; 146: 1010-1018.
-
(2005)
Br J Pharmacol
, vol.146
, pp. 1010-1018
-
-
Guilluy, C.1
Sauzeau, V.2
Rolli-Derkinderen, M.3
-
12
-
-
14244260105
-
Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
-
Fukumoto Y, Matoba T, Ito A, et al. Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart 2005; 91: 391-392.
-
(2005)
Heart
, vol.91
, pp. 391-392
-
-
Fukumoto, Y.1
Matoba, T.2
Ito, A.3
-
13
-
-
31644431508
-
Beneficial acute effects of rhokinase inhibitor in patients with pulmonary arterial hypertension
-
Ishikura K, Yamada N, Ito M, et al. Beneficial acute effects of rhokinase inhibitor in patients with pulmonary arterial hypertension. Circ J 2006; 70: 174-178.
-
(2006)
Circ J
, vol.70
, pp. 174-178
-
-
Ishikura, K.1
Yamada, N.2
Ito, M.3
-
14
-
-
77950921360
-
Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension
-
Fujita H, Fukumoto Y, Saji K, et al. Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension. Heart Vessels 2010; 25: 144-149.
-
(2010)
Heart Vessels
, vol.25
, pp. 144-149
-
-
Fujita, H.1
Fukumoto, Y.2
Saji, K.3
-
15
-
-
67449105737
-
RhoA and Rho kinase activation in human pulmonary hypertension: Role of 5-HT signaling
-
Guilluy C, Eddahibi S, Agard C, et al. RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling. Am J Respir Crit Care Med 2009; 179: 1151-1158.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 1151-1158
-
-
Guilluy, C.1
Eddahibi, S.2
Agard, C.3
-
16
-
-
77957832881
-
Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: Comparison with bosentan and sildenafil
-
Mouchaers KTB, Schalij I, de Boer MA, et al. Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil. Eur Respir J 2010; 36: 800-807.
-
(2010)
Eur Respir J
, vol.36
, pp. 800-807
-
-
Mouchaers, K.T.B.1
Schalij, I.2
De Boer, M.A.3
-
17
-
-
0032578279
-
Primary pulmonary hypertension
-
Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet 1998; 352: 719-725.
-
(1998)
Lancet
, vol.352
, pp. 719-725
-
-
Gaine, S.P.1
Rubin, L.J.2
-
18
-
-
14044274307
-
The right ventricle in pulmonary hypertension
-
Chin KM, Kim NH, Rubin LJ. The right ventricle in pulmonary hypertension. Coron Artery Dis 2005; 16: 13-18.
-
(2005)
Coron Artery Dis
, vol.16
, pp. 13-18
-
-
Chin, K.M.1
Kim, N.H.2
Rubin, L.J.3
-
19
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006; 7: 589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
20
-
-
4544383466
-
Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
-
DOI 10.1183/09031936.04.00028404
-
Humbert M, Barst RJ, Robbins IM, et al. Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2. Eur Respir J 2004; 24: 353-359. (Pubitemid 39232254)
-
(2004)
European Respiratory Journal
, vol.24
, Issue.3
, pp. 353-359
-
-
Humbert, M.1
Barst, R.J.2
Robbins, I.M.3
Channick, R.N.4
Galie, N.5
Boonstra, A.6
Rubin, L.J.7
Horn, E.M.8
Manes, A.9
Simonneau, G.10
-
21
-
-
33845526777
-
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
-
McLaughlin VV, Oudiz RJ, Frost A, et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med 2006; 174: 1257-1263.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 1257-1263
-
-
McLaughlin, V.V.1
Oudiz, R.J.2
Frost, A.3
-
22
-
-
34547941265
-
Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats
-
DOI 10.1097/FJC.0b013e31806befe6, PII 0000534420070800000012
-
Tawara S, Fukumoto Y, Shimokawa H. Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats. J Cardiovasc Pharmacol 2007; 50: 195-200. (Pubitemid 47267745)
-
(2007)
Journal of Cardiovascular Pharmacology
, vol.50
, Issue.2
, pp. 195-200
-
-
Tawara, S.1
Fukumoto, Y.2
Shimokawa, H.3
-
23
-
-
33644837177
-
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats
-
Weigand L, Sylvester JT, Shimoda LA. Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 2006; 290: L284-L290.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Weigand, L.1
Sylvester, J.T.2
Shimoda, L.A.3
-
24
-
-
0036873027
-
Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: A multicenter study
-
Shimokawa H, Hiramori K, Iinuma H, et al. Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: a multicenter study. J Cardiovasc Pharmacol 2002; 40: 751-761.
-
(2002)
J Cardiovasc Pharmacol
, vol.40
, pp. 751-761
-
-
Shimokawa, H.1
Hiramori, K.2
Iinuma, H.3
|