Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells

FASEB Journal

Volumn 24, Issue 10, 2010, Pages 3706-3719

  Huichalaf, Claudia ^a   Sakai, Keiko ^a   Jin, Bingwen ^a   Jones, Karlie ^a   Wang, Guo Li ^a   Schoser, Benedikt ^b   Schneider Gold, Christiane ^c   Sarkar, Partha ^d   Pereira Smith, Olivia M ^e   Timchenko, Nikolai ^a   Timchenko, Lubov ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c ST JOSEF HOSPITAL   (Germany)

^d Managed Health Care Division   (United States)

^e Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

CUG binding protein; CUGBP1; MRG15 MORF; PKR

Indexed keywords

CUG RNA; CYTOPLASM PROTEIN; INITIATION FACTOR 2ALPHA; MESSENGER RNA; PROTEIN CUGBP1; PROTEIN KINASE R; PROTEIN MRG15; PROTEIN TIA 1; RNA; UNCLASSIFIED DRUG; CELF1 PROTEIN, HUMAN; PROTEIN BINDING; RNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRESS; CONTROLLED STUDY; DNA REPAIR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GEL CHROMATOGRAPHY; GENETICS; METABOLISM; MYOTONIC DYSTROPHY; NORTHERN BLOTTING; PATHOLOGY; PHOSPHORYLATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRINUCLEOTIDE REPEAT; WESTERN BLOTTING;

BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CHROMATOGRAPHY, GEL; DNA REPAIR; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MYOTONIC DYSTROPHY; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA-BINDING PROTEINS; TRINUCLEOTIDE REPEATS;

EID: 77957845571     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-151159     Document Type: Article

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