A new method for measuring the dynamic shape change of platelets

Transfusion Medicine and Hemotherapy

Volumn 37, Issue 5, 2010, Pages 306-310

  Kraus, Max Joseph ^a   Strasser, Erwin F ^a   Eckstein, Reinhold ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Light microscopy; Platelet activation; Platelet function; Platelets; Shape change; Thrombocytes

Indexed keywords

CITRATE SODIUM;

ARTICLE; AUTOMATION; BLOOD SAMPLING; CAMERA; COMPUTER PROGRAM; FILOPODIUM; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MICROSCOPY; NORMAL HUMAN; PHOTOGRAPHY; PSEUDOPODIUM; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION; THROMBOCYTE RICH PLASMA;

EID: 77957844779     PISSN: 16603796     EISSN: None     Source Type: Journal    
DOI: 10.1159/000320723     Document Type: Article

References (11)

1. Gear ARL, Polanowska-Grabowska RK: The platelet shape change, in Gresele CPPP, Vermylen J (eds): Platelets in Thrombotic and Non-Throm-botic Disorders: Pathophysiology, Pharmacology and Therapeutics. Cambridge, Cambridge University Press, 2002, pp 319-322
2. Hartwig JH: The platelet cytoskeleton, in Michel-son AD (ed): Platelets. New York, Academic Press, 2007, pp 75-86
3. Allen RD, Zacharski LR, Widirstky ST, Rosen-stein R, Zaitlin LM, Burgess DR: Transfor mation and motility of human platelets: details of the shape change and release reaction observed by optical and electron microscopy. J Cell Biol 1979; 83:126-142
4. Maurer-Spurej E, Pfeiler G, Maurer N, Lindner H, Glatter O, Devine DV: Room temperature activates human blood platelets. Laboratory investigation 2001;81:581-592
5. Leven RM, Gonnella PA, Reeber MJ, Nachmias VT: Platelet shape change and cytoskeletal assembly: effects of pH and monovalent cation iono-phores. Thromb Haemost 1983;49:230-234
6. Paul BZ, Daniel JL, Kunapuli SP: Platelet shape change is mediated by both calcium-dependent and-independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein ki-nase in platelet shape change. J Biol Chem 1999; 274:28293-28300
7. Southwick FS: Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells. Proc Natl Acad Sci \USA 2000;97:6936-6938
8. Rosenstein R, Zacharski LR, Allen RD: Quan-titation of human platelet transformation on sili-conized glass: comparison of 'normal' and 'abnormal' platelets. Thromb Haemost 1981;46:521-524
9. Zobel CR, Woods A: Effect of calcium on the morphology of human platelets spread on glass substrates. Eur J Cell Biol 1983;30: 83-92
10. Breddin K, Ziemen M, Grun H, Bauer O, Herrmann W: Formwandel und Funktionsverhalten der Thrombozyten nach der Blutentnahme. Onko- hämostaseologie. 1976:297-304
11. Cenni E, Stea S, Cervellati M, Pizzoferrato A, Montanaro L: Quantitative evaluation by image analysis of platelet morphological modifications after contact with polyvinylacetate. Minerva Car-dioangiol 2000;48:1-8