CztR, a LysR-type transcriptional regulator involved in zinc homeostasis and oxidative stress defense in Caulobacter crescentus

Journal of Bacteriology

Volumn 192, Issue 20, 2010, Pages 5480-5488

  Braz, Vânia S ^a   Da Silva Neto, José F ^a   Italiani, Valéria C S ^a   Marques, Marilis V ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BETA GALACTOSIDASE; CADMIUM; HYDROGEN PEROXIDE; KATG PROTEIN; PARAQUAT; PROTEIN AHPC; PROTEIN CZTR; REGULATOR PROTEIN; SUPEROXIDE; SUPEROXIDE DISMUTASE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; AUTOREGULATION; BACTERIAL STRAIN; BACTERIUM MUTANT; CAULOBACTER CRESCENTUS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE INSERTION; GENE ISOLATION; GENETIC TRANSCRIPTION; HOMEOSTASIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TRANSPOSON; CAULOBACTER VIBRIOIDES; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY;

CAULOBACTER VIBRIOIDES;

BACTERIAL PROTEINS; CAULOBACTER CRESCENTUS; GENE EXPRESSION REGULATION, BACTERIAL; HOMEOSTASIS; MUTATION; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC; ZINC;

EID: 77957831183     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.00496-10     Document Type: Article

References (39)

1. Banjerdkij, P., P. Vattanaviboon, and S. Mongkolsuk. 2005. Exposure to cadmium elevates expression of genes in the OxyR and OhrR regulons and induces cross-resistance to peroxide killing treatment in Xanthomonas campestris. Appl. Environ. Microbiol. 71:1843-1849.
2. Beard, S. J., R. Hashim, G. Wu, M. R. Binet, M. N. Hughes, and R. K. Poole. 2000. Evidence for the transport of zinc(II) ions via the pit inorganic phosphate transport system in Escherichia coli. FEMS Microbiol. Lett. 184:231-235.
3. Belitsky, B. R., and A. L. Sonenshein. 1997. Altered transcription activation specificity of a mutant form of Bacillus subtilis GltR, a LysR family member. J. Bacteriol. 179:1035-1043.
4. Braz, V. S., and M. V. Marques. 2005. Genes involved in cadmium resistance in Caulobacter crescentus. FEMS Microbiol. Lett. 251:289-295.
5. Ely, B. 1991. Genetics of Caulobacter crescentus. Methods Enzymol. 204:372-384.
6. Evinger, M., and N. Agabian. 1977. Envelope-associated nucleoid from Caulobacter crescentus stalked and swarmer cells. J. Bacteriol. 132:294-301.
7. Gober, J. W., and L. Shapiro. 1992. A developmentally regulated Caulobacter flagellar promoter is activated by 3′ enhancer and IHF binding elements. Mol. Biol. Cell 3:913-926.
8. Goethals, K., M. Van Montagu, and M. Holsters. 1992. Conserved motifs in a divergent nod box of Azorhizobium caulinodans ORS571 reveal a common structure in promoters regulated by LysR-type proteins. Proc. Natl. Acad. Sci. U. S. A. 89:1646-1650.
9. Grass, G., S. Franke, N. Taudte, D. H. Nies, L. M. Kucharski, M. E. Maguire, and C. Rensing. 2005. The metal permease ZupT from Escherichia coli is a transporter with a broad substrate spectrum. J. Bacteriol. 187:1604-1611.
10. Hanahan, D. 1983. Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166:557.
11. Hantke, K. 2001. Bacterial zinc transporters and regulators. BioMetals Rev. 14:239-249.
12. Hu, P., E. L. Brodie, Y. Suzuki, H. H. McAdams, and G. L. Andersen. 2005. Whole-genome transcriptional analysis of heavy metal stresses in Caulobacter crescentus. J. Bacteriol. 187:8437-8449.
13. Huang, D. L., T. J. Tang, Q. Liao, H. C. Li, Q. Chen, Y. Q. He, J. X. Feng, B. L. Jiang, G. T. Lu, B. Chen, and J. L. Tang. 2008. The Zur of Xanthomonas campestris functions as a repressor and activator of putative zinc homeostasis genes via recognizing two distinct sequences within its target promoters. Nucleic Acids Res. 36:4295-4309.
14. Ieva, R., C. Alaimo, I. Delany, G. Spohn, R. Rappuoli, and V. Scarlato. 2005. CrgA is an inducible LysR-type regulator of Neisseria meningitidis, acting both as a repressor and as an activator of gene transcription. J. Bacteriol. 187:3421-3430.
15. Italiani, V. C. S., V. S. Braz, H. Xiao, H. M. Steinman, and M. V. Marques. 2010. Catalase-peroxidase activity is decreased in a Caulobacter crescentus rho mutant. FEMS Microbiol. Lett. 303:48-54.
16. Lang, E. A., and M. V. Marques. 2004. Identification and transcriptional control of Caulobacter crescentus genes encoding proteins containing a cold shock domain. J. Bacteriol. 186:5603-5613.
17. Maddocks, S. E., and P. C. Oyston. 2008. Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins. Microbiology 154:3609-3623.
18. Malakooti, J., and B. Ely. 1994. Identification and characterization of the ilvR gene encoding a LysR-type regulator of Caulobacter crescentus. J. Bacteriol. 176:1275-1281.
19. Martínez-Costa, O. H., A. J. Martín-Triana, E. Martínez, M. A. Fernández-Moreno, and F. Malpartida. 1999. An additional regulatory gene for actinorhodin production in Streptomyces lividans involves a LysR-Type transcriptional regulator. J. Bacteriol. 181:4353-4364.
20. McGrath, P. T., H. Lee, L. Zhang, A. A. Iniesta, A. K. Hottes, M. H. Tan, N. J. Hillson, P. Hu, L. Shapiro, and H. H. McAdams. 2007. High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons. Nat. Biotechnol. 25:584-592.
21. Meisenzahl, A. C., L. Shapiro, and U. Jenal. 1997. Isolation and characterization of a xylose-dependent promoter from Caulobacter crescentus. J. Bacteriol. 179:592-600.
22. Messner, K. R., and J. A. Imlay. 1999. The identification of primary sites of superoxide and hydrogen peroxide formation in the aerobic respiratory chain and sulfite reductase complex of Escherichia coli. J. Biol. Chem. 274:10119-10128.
23. Miller, J. H. 1972. Experiments in molecular genetics. A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. Nierman, W. C., T. V. Feldblyum, M. T. Laub, I. T. Paulsen, K. E. Nelson, J. A. Eisen, J. F. Heidelberg, M. R. Alley, N. Ohta, J. R. Maddock, I. Potocka, W. C. Nelson, A. Newton, C. Stephens, N. D. Phadke, B. Ely, R. T. DeBoy, R. J. Dodson, A. S. Durkin, M. L. Gwinn, D. H. Haft, J. F. Kolonay, J. Smit, M. B. Craven, H. Khouri, J. Shetty, K. Berry, T. Utterback, K. Tran, A. Wolf, J. Vamathevan, M. Ermolaeva, O. White, S. L. Salzberg, J. C. Venter, L. Shapiro, C. M. Fraser, and J. Eisen. 2001. Complete genome sequence of Caulobacter crescentus. Proc. Natl. Acad. Sci. U. S. A. 98:4136-4141.
25. Outten, C. E., D. A. Tobin, J. E. Penner-Hahn, and T. V. O'Halloran. 2001. Characterization of the metal receptor sites in Escherichia coli Zur, an ultrasensitive zinc(II) metalloregulatory protein. Biochemistry 40:10417-10423.
26. Patzer, S. I., and K. Hantke. 1998. The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli. Mol. Microbiol. 28:1199-1210.
27. Picossi, S., B. R. Belitsky, and A. L. Sonenshein. 2007. Molecular mechanism of the regulation of Bacillus subtilis gltAB expression by GltC. J. Mol. Biol. 365:1298-1313.
28. Prentki, P., and H. M. Krisch. 1984. In vitro insertional mutagenesis with a selectable DNA fragment. Gene 29:303-313.
29. Roberts, R. C., C. Toochinda, M. Avedissian, R. L. Baldini, S. L. Gomes, and L. Shapiro. 1996. Identification of a Caulobacter crescentus operon encoding hrcA, involved in negatively regulating heat-inducible transcription and the chaperone gene grpE. J. Bacteriol. 178:1829-1841.
30. Schell, M. A. 1993. Molecular biology of the LysR family of transcriptional regulators. Annu. Rev. Microbiol. 47:597-626.
31. Shibata, M., H. Katoh, M. Sonoda, H. Ohkawa, M. Shimoyama, H. Fukuzawa, A. Kaplan, and T. Ogawa. 2002. Genes essential to sodium-dependent bicarbonate transport in cyanobacteria: function and phylogenetic analysis. J. Biol. Chem. 277:18658-18664.
32. Simon, R., U. Priefer, and A. Pühler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram negative bacteria. Nat. Biotechnol. 1:784-791.
33. Steinman, H. M., F. Fareed, and L. Weinstein. 1997. Catalase-peroxidase of Caulobacter crescentus: function and role in stationary phase survival. J. Bacteriol. 179:6831-6836.
34. Stephens, C., B. Christen, K. Watanabe, T. Fuchs, and U. Jenal. 2007. Regulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor. J. Bacteriol. 189:8828-8834.
35. Stohs, S. J., and D. Bagchi. 1995. Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med. 18:321-336.
36. Storz, G., and M. Zheng. 2000. Oxidative stress, p. 47-59. In G. Storz and R. Hengge-Aronis (ed.), Bacterial stress responses. ASM Press, Washington, DC.
37. von Rozycki, T., M. A. Schultzel, and M. H. Saier, Jr. 2004. Sequence analyses of cyanobacterial bicarbonate transporters and their homologues. J. Mol. Microbiol. Biotechnol. 7:102-108.
38. Wang, H. L., B. L. Postier, and R. L. Burnap. 2004. Alterations in global patterns of gene expression in Synechocystis sp. PCC 6803 in response to inorganic carbon limitation and the inactivation of ndhR, a LysR family regulator. J. Biol. Chem. 279:5739-5751.
39. Wortinger, M. A., E. M. Quardokus, and Y. V. Brun. 1998. Morphological adaptation and inhibition of cell division during stationary phase in Caulobacter crescentus. Mol. Microbiol. 29:963-973.