Activation of mTOR and RhoA is a major mechanism by which ceramide 1-phosphate stimulates macrophage proliferation

Cellular Signalling

Volumn 23, Issue 1, 2011, Pages 27-34

  Gangoiti, Patricia ^a   Arana, Lide ^a   Ouro, Alberto ^a   Granado, Maria H ^a   Trueba, Miguel ^a   Gómez Muñoz, Antonio ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Ceramide 1 phosphate; MTOR; Phosphoinositide 3 kinase; Protein kinase B; RhoA; Sphingolipids

Indexed keywords

CERAMIDE 1 PHOSPHATE; DNA; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PROLINE RICH AKT SUBSTRATE 40 KDA; RHEB PROTEIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; S6 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL GROWTH; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; INHIBITION KINETICS; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL PROLIFERATION; CELLS, CULTURED; CERAMIDES; FEMALE; MACROPHAGES; MICE; MONOMERIC GTP-BINDING PROTEINS; NEUROPEPTIDES; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEINS; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

MAMMALIA;

EID: 77957823928     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.08.001     Document Type: Article

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