메뉴 건너뛰기




Volumn 9, Issue 4, 2010, Pages 212-218

The timing of chemotherapy and surgery for the treatment of colorectal liver metastases

Author keywords

Bevacizumab; Cetuximab; FOLFIRI; FOLFOX; FOLFOXIRI; Neoadjuvant chemotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAPECITABINE; CETUXIMAB; CYTOTOXIC AGENT; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; VASCULOTROPIN;

EID: 77957818218     PISSN: 15330028     EISSN: None     Source Type: Journal    
DOI: 10.3816/CCC.2010.n.031     Document Type: Review
Times cited : (41)

References (72)
  • 1
    • 33748101222 scopus 로고    scopus 로고
    • Towards a pan-European consensus on the treatment of patients with colorectal liver metastases
    • Van Cutsem E, Nordlinger B, Adam R, et al. Towards a pan-European consensus on the treatment of patients with colorectal liver metastases. Eur J Cancer 2006; 42:2212-21.
    • (2006) Eur J Cancer , vol.42 , pp. 2212-2221
    • Van Cutsem, E.1    Nordlinger, B.2    Adam, R.3
  • 2
    • 68949094312 scopus 로고    scopus 로고
    • Improved survival in metastatic colorec-tal cancer is associated with adoption of hepatic resection and improved chemotherapy
    • Kopetz S, Chang GJ, Overman MJ, et al. Improved survival in metastatic colorec-tal cancer is associated with adoption of hepatic resection and improved chemo-therapy J Clin Oncol 2009; 27:3677-83.
    • (2009) J Clin Oncol , vol.27 , pp. 3677-3683
    • Kopetz, S.1    Chang, G.J.2    Overman, M.J.3
  • 3
    • 0038600610 scopus 로고    scopus 로고
    • Chemotherapy and surgery: New perspectives on the treatment of unre-sectable liver metastases
    • Adam R. Chemotherapy and surgery: new perspectives on the treatment of unre-sectable liver metastases. Ann Oncol 2003; 14(suppl 2):ii13-6.
    • (2003) Ann Oncol , vol.14 , Issue.SUPPL. 2
    • Adam, R.1
  • 4
    • 34548476513 scopus 로고    scopus 로고
    • Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group
    • Nordlinger B, Van Cutsem E, Rougier P, et al. Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group. Eur J Cancer 2007; 43:2037-45.
    • (2007) Eur J Cancer , vol.43 , pp. 2037-2045
    • Nordlinger, B.1    Van Cutsem, E.2    Rougier, P.3
  • 5
    • 67649780943 scopus 로고    scopus 로고
    • A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases
    • Bathe OF, Ernst S, Sutherland FR, et al. A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases. BMC Cancer 2009; 9:156.
    • (2009) BMC Cancer , vol.9 , pp. 156
    • Bathe, O.F.1    Ernst, S.2    Sutherland, F.R.3
  • 6
    • 44149107591 scopus 로고    scopus 로고
    • Importance of response to neoadjuvant chemotherapy in potentially curable colorectal cancer liver metasta-ses
    • Gruenberger B, Scheithauer W, Punzengruber R, et al. Importance of response to neoadjuvant chemotherapy in potentially curable colorectal cancer liver metasta-ses. BMC Cancer 2008; 8:120.
    • (2008) BMC Cancer , vol.8 , pp. 120
    • Gruenberger, B.1    Scheithauer, W.2    Punzengruber, R.3
  • 7
    • 40749149728 scopus 로고    scopus 로고
    • Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): A randomised controlled trial
    • Nordlinger B, Sorbye H, Glimelius B, et al. Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 2008; 371:1007-16.
    • (2008) Lancet , vol.371 , pp. 1007-1016
    • Nordlinger, B.1    Sorbye, H.2    Glimelius, B.3
  • 8
    • 23844448040 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates
    • Folprecht G, Grothey A, Alberts S, et al. Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates. Ann Oncol 2005; 16:1311-9.
    • (2005) Ann Oncol , vol.16 , pp. 1311-1319
    • Folprecht, G.1    Grothey, A.2    Alberts, S.3
  • 9
    • 38349091716 scopus 로고    scopus 로고
    • Colorectal cancer metastasis resectability after treatment with the combination of oxaliplatin, irinotecan and 5-fluorouracil. Final results of a phase II study
    • Abad A, Massuti B, Antón A, et al. Colorectal cancer metastasis resectability after treatment with the combination of oxaliplatin, irinotecan and 5-fluorouracil. Final results of a phase II study. Acta Oncol 2008; 47:286-92.
    • (2008) Acta Oncol , vol.47 , pp. 286-292
    • Abad, A.1    Massuti, B.2    Antón, A.3
  • 10
    • 33644819672 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovo-rin for patients with unresectable liver-only metastases from colorectal cancer: A North Central Cancer Treatment Group phase II study
    • Alberts SR, Horvath WL, Sternfeld WC, et al. Oxaliplatin, fluorouracil, and leucovo-rin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study. J Clin Oncol 2005; 23:9243-9.
    • (2005) J Clin Oncol , vol.23 , pp. 9243-9249
    • Alberts, S.R.1    Horvath, W.L.2    Sternfeld, W.C.3
  • 11
    • 35348905517 scopus 로고    scopus 로고
    • Final analysis of colorectal cancer patients treated with irinotecan and 5-fluorouracil plus folinic acid neoadjuvant chemo-therapy for unresectable liver metastases
    • Barone C, Nuzzo G, Cassano A, et al. Final analysis of colorectal cancer patients treated with irinotecan and 5-fluorouracil plus folinic acid neoadjuvant chemo-therapy for unresectable liver metastases. Br J Cancer 2007; 97:1035-9.
    • (2007) Br J Cancer , vol.97 , pp. 1035-1039
    • Barone, C.1    Nuzzo, G.2    Cassano, A.3
  • 12
    • 0029794696 scopus 로고    scopus 로고
    • Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy
    • discussion 520-2
    • Bismuth H, Adam R, Lévi F, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy Ann Surg 1996; 224:509, discussion 520-2.
    • (1996) Ann Surg , vol.224 , pp. 509
    • Bismuth, H.1    Adam, R.2    Lévi, F.3
  • 13
    • 34249000361 scopus 로고    scopus 로고
    • Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
    • Falcone A, Ricci S, Brunetti I, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol 2007; 25:1670-6.
    • (2007) J Clin Oncol , vol.25 , pp. 1670-1676
    • Falcone, A.1    Ricci, S.2    Brunetti, I.3
  • 14
    • 0032791959 scopus 로고    scopus 로고
    • Long-term survival of patients with unre-sectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil leucovorin oxaliplatin and surgery
    • Giacchetti S, Itzhaki M, Gruia G, et al. Long-term survival of patients with unre-sectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery Ann Oncol 1999; 10:663-9.
    • (1999) Ann Oncol , vol.10 , pp. 663-669
    • Giacchetti, S.1    Itzhaki, M.2    Gruia, G.3
  • 15
    • 23844544714 scopus 로고    scopus 로고
    • Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: A multicenter phase II study by the Cancer Therapeutic Research Group
    • Ho WM, Ma B, Mok T, et al. Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group. Med Oncol 2005; 22:303-12.
    • (2005) Med Oncol , vol.22 , pp. 303-312
    • Ho, W.M.1    Ma, B.2    Mok, T.3
  • 16
    • 39149097520 scopus 로고    scopus 로고
    • Triplet combination of fluoropyrimidines, ox-aliplatin, and irinotecan in the first-line treatment of metastatic colorectal cancer
    • Masi G, Vasile E, Loupakis F, et al. Triplet combination of fluoropyrimidines, ox-aliplatin, and irinotecan in the first-line treatment of metastatic colorectal cancer. Clin Colorectal Cancer 2008; 7:7-14.
    • (2008) Clin Colorectal Cancer , vol.7 , pp. 7-14
    • Masi, G.1    Vasile, E.2    Loupakis, F.3
  • 17
    • 2642541197 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients
    • Pozzo C, Basso M, Cassano A, et al. Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients. Ann Oncol 2004; 15:933-9.
    • (2004) Ann Oncol , vol.15 , pp. 933-939
    • Pozzo, C.1    Basso, M.2    Cassano, A.3
  • 18
    • 20044370825 scopus 로고    scopus 로고
    • Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: A phase I-II study
    • Seium Y, Stupp R, Ruhstaller T, et al. Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study. Ann Oncol 2005; 16:762-6.
    • (2005) Ann Oncol , vol.16 , pp. 762-766
    • Seium, Y.1    Stupp, R.2    Ruhstaller, T.3
  • 19
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, André T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22:229-37.
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    André, T.2    Achille, E.3
  • 20
    • 33644843853 scopus 로고    scopus 로고
    • OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer-a GERCOR study
    • Tournigand C, Cervantes A, Figer A, et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer-a GERCOR study. J Clin Oncol 2006; 24:394-400.
    • (2006) J Clin Oncol , vol.24 , pp. 394-400
    • Tournigand, C.1    Cervantes, A.2    Figer, A.3
  • 21
    • 0035698112 scopus 로고    scopus 로고
    • Impact of surgery on survival in palliative patients with metastatic colorectal cancer after first line treatment with weekly 24-hour infusion of high-dose 5-fluorouracil and folinic acid
    • Wein A, Riedel C, Kockerling F, et al. Impact of surgery on survival in palliative patients with metastatic colorectal cancer after first line treatment with weekly 24-hour infusion of high-dose 5-fluorouracil and folinic acid. Ann Oncol 2001; 12:1721-7.
    • (2001) Ann Oncol , vol.12 , pp. 1721-1727
    • Wein, A.1    Riedel, C.2    Kockerling, F.3
  • 22
    • 43749090901 scopus 로고    scopus 로고
    • Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): A phase II study in colorectal cancer patients with non-resectable liver metastases
    • Ychou M, Viret F, Kramar A, et al. Tritherapy with fluorouracil/ leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases. Cancer Chemother Pharmacol 2008; 62:195-201.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 195-201
    • Ychou, M.1    Viret, F.2    Kramar, A.3
  • 23
    • 30944445619 scopus 로고    scopus 로고
    • Treatment with 5-fluorouracil/folinic acid, oxaliplatin, and irinotecan enables surgical resection of metastases in patients with initially unresectable metastatic colorectal cancer
    • Masi G, Cupini S, Marcucci L, et al. Treatment with 5-fluorouracil/ folinic acid, oxaliplatin, and irinotecan enables surgical resection of metastases in patients with initially unresectable metastatic colorectal cancer. Ann Surg Oncol 2006; 13:58-65.
    • (2006) Ann Surg Oncol , vol.13 , pp. 58-65
    • Masi, G.1    Cupini, S.2    Marcucci, L.3
  • 24
    • 59949091448 scopus 로고    scopus 로고
    • Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
    • Bokemeyer C, Bondarenko I, Makhson A, et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009; 27:663-71
    • (2009) J Clin Oncol , vol.27 , pp. 663-671
    • Bokemeyer, C.1    Bondarenko, I.2    Makhson, A.3
  • 25
    • 70349690209 scopus 로고    scopus 로고
    • Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial
    • Okines A, Puerto OD, Cunningham D, et al. Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial. Br J Cancer 2009; 101:1033-8.
    • (2009) Br J Cancer , vol.101 , pp. 1033-1038
    • Okines, A.1    Puerto, O.D.2    Cunningham, D.3
  • 26
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Köhne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360:1408-17.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Köhne, C.H.2    Hitre, E.3
  • 27
    • 77049118446 scopus 로고    scopus 로고
    • Induction of resectability of colorectal liver metastases (CLM) with cetuximab (Cmab) plus CPT-11/5-fluorouracil (5-FU)/leucovorin(FA)/oxaliplatin (L-OHP) (CPT-11-FFL) (POCHER trial)
    • P-6086
    • Garufi C, Torsello A, Tumolo S, et al. Induction of resectability of colorectal liver metastases (CLM) with cetuximab (Cmab) plus CPT-11/5-fluorouracil (5-FU)/leucovorin(FA)/oxaliplatin (L-OHP) (CPT-11-FFL) (POCHER trial). Eur J Can-cer Supplements 2009; 7:348(P-6086).
    • (2009) Eur J Can-cer Supplements , vol.7 , pp. 348
    • Garufi, C.1    Torsello, A.2    Tumolo, S.3
  • 29
    • 63449116518 scopus 로고    scopus 로고
    • Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxali-platin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases
    • Masi G, Loupakis F, Pollina L, et al. Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxali-platin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases. Ann Surg 2009; 249:420-5.
    • (2009) Ann Surg , vol.249 , pp. 420-425
    • Masi, G.1    Loupakis, F.2    Pollina, L.3
  • 30
    • 84898691746 scopus 로고    scopus 로고
    • Preliminary results of a multicentre phase II trial evaluating cetuximab in combination with FOLFIRINOX (LV5FU + Irinotecan + Oxaliplatin) as first line treatment of metastatic colorectal cancer (mCRC) patients
    • January 15-17, 2009; San Francisco, CA Abstract 450
    • Ychou M, Desseigne F, Thezenas S, et al. Preliminary results of a multicentre phase II trial evaluating cetuximab in combination with FOLFIRINOX (LV5FU + Irinotecan + Oxaliplatin) as first line treatment of metastatic colorectal cancer (mCRC) patients. Presented at: the American Society of Clinical Oncology: 2009 Gastrointestinal Cancers Symposium; January 15-17, 2009; San Francisco, CA Abstract 450.
    • Presented At: The American Society of Clinical Oncology: 2009 Gastrointestinal Cancers Symposium
    • Ychou, M.1    Desseigne, F.2    Thezenas, S.3
  • 31
    • 33644697486 scopus 로고    scopus 로고
    • Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma
    • Folprecht G, Lutz MP, Schoffski P, et al. Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. Ann Oncol 2006; 17:450-6.
    • (2006) Ann Oncol , vol.17 , pp. 450-456
    • Folprecht, G.1    Lutz, M.P.2    Schoffski, P.3
  • 32
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: The CELIM randomised phase 2 trial
    • Folprecht G, Gruenberger T, Bechstein WO, et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 2010; 11:38-47.
    • (2010) Lancet Oncol , vol.11 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3
  • 33
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 34
    • 33750288107 scopus 로고    scopus 로고
    • Preliminary results from a phase II study of infusional 5-FU, leucovorin and irinotecan (FOLFIRI) plus bevacizumab as first-line treatment for metastatic colorectal cancer (mCRC)
    • Kopetz S, Abbruzzese JL, Eng C, et al. Preliminary results from a phase II study of infusional 5-FU, leucovorin and irinotecan (FOLFIRI) plus bevacizumab as first-line treatment for metastatic colorectal cancer (mCRC). J Clin Oncol 2006; 24(18 suppl):165s (abstract 3579).
    • (2006) J Clin Oncol , vol.24 , Issue.18 SUPPL.
    • Kopetz, S.1    Abbruzzese, J.L.2    Eng, C.3
  • 35
    • 65649086838 scopus 로고    scopus 로고
    • Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: A multicentre two-part phase I/II study
    • Raoul JL, Van Laethem JL, Peeters M, et al. Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study. BMC Cancer 2009; 9:112.
    • (2009) BMC Cancer , vol.9 , pp. 112
    • Raoul, J.L.1    Van Laethem, J.L.2    Peeters, M.3
  • 36
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxali-platin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz LB, Clarke S, Díaz-Rubio E, et al. Bevacizumab in combination with oxali-platin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008; 26:2013-9.
    • (2008) J Clin Oncol , vol.26 , pp. 2013-2019
    • Saltz, L.B.1    Clarke, S.2    Díaz-Rubio, E.3
  • 37
    • 36749067866 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treat-ment of metastatic colorectal cancer
    • Tabernero J, Van Cutsem E, Díaz-Rubio E, et al. Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treat-ment of metastatic colorectal cancer. J Clin Oncol 2007; 25:5225-32.
    • (2007) J Clin Oncol , vol.25 , pp. 5225-5232
    • Tabernero, J.1    Van Cutsem, E.2    Díaz-Rubio, E.3
  • 38
    • 70449528360 scopus 로고    scopus 로고
    • Cetuximab plus FOLFOX6 or cetuximab plus FOLFIRI as neoadjuvant treatment of nonresectable colorectal liver metastases: A randomized multicenter study (CELIM-study)
    • January 15-17, 2009; San Francisco, CA. Abstract 296
    • Folprecht G, Gruenberger T, Hartmann JT, et al. Cetuximab plus FOLFOX6 or cetuximab plus FOLFIRI as neoadjuvant treatment of nonresectable colorectal liver metastases: A randomized multicenter study (CELIM-study). Presented at: the American Society of Clinical Oncology: 2009 Gastrointestinal Cancers Sym-posium; January 15-17, 2009; San Francisco, CA. Abstract 296.
    • Presented At: The American Society of Clinical Oncology: 2009 Gastrointestinal Cancers Symposium
    • Folprecht, G.1    Gruenberger, T.2    Hartmann, J.T.3
  • 39
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leu-covorin as adjuvant treatment for colon cancer
    • André T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leu-covorin as adjuvant treatment for colon cancer. N Engl J Med 2004; 350:2343-51.
    • (2004) N Engl J Med , vol.350 , pp. 2343-2351
    • André, T.1    Boni, C.2    Mounedji-Boudiaf, L.3
  • 40
    • 0037087721 scopus 로고    scopus 로고
    • Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: Surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy-an intergroup study
    • Kemeny MM, Adak S, Gray B, et al. Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy-an intergroup study. J Clin Oncol 2002; 20:1499-505.
    • (2002) J Clin Oncol , vol.20 , pp. 1499-1505
    • Kemeny, M.M.1    Adak, S.2    Gray, B.3
  • 41
    • 33750962938 scopus 로고    scopus 로고
    • Multicenter randomized trial of adjuvant fluoro-uracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial
    • Portier G, Elias D, Bouche O, et al. Multicenter randomized trial of adjuvant fluoro-uracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial. J Clin Oncol 2006; 24:4976-82.
    • (2006) J Clin Oncol , vol.24 , pp. 4976-4982
    • Portier, G.1    Elias, D.2    Bouche, O.3
  • 42
    • 54449087716 scopus 로고    scopus 로고
    • Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: A pooled analysis of two randomized trials
    • Mitry E, Fields AL, Bleiberg H, et al. Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: A pooled analysis of two randomized trials. J Clin Oncol 2008; 26:4906-11.
    • (2008) J Clin Oncol , vol.26 , pp. 4906-4911
    • Mitry, E.1    Fields, A.L.2    Bleiberg, H.3
  • 43
    • 0033619892 scopus 로고    scopus 로고
    • Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer
    • Kemeny N, Huang Y, Cohen AM, et al. Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer. N Engl J Med 1999; 341:2039-48.
    • (1999) N Engl J Med , vol.341 , pp. 2039-2048
    • Kemeny, N.1    Huang, Y.2    Cohen, A.M.3
  • 44
    • 0345455373 scopus 로고    scopus 로고
    • Fluorouracil (FU) plus l-leucovorin (l-LV) versus observation after potentially curative resection of liver or lung metastases from colorectal cancer (CRC): Results of the ENG (EORTC/NCIC CTG/GIVIO) randomized trial
    • abstract 592
    • Langer B, Bleiberg H, Labianca R, et al. Fluorouracil (FU) plus l-leucovorin (l-LV) versus observation after potentially curative resection of liver or lung metastases from colorectal cancer (CRC): results of the ENG (EORTC/NCIC CTG/GIVIO) randomized trial. Proc Am Soc Clin Oncol 2002; 21:149a (abstract 592).
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Langer, B.1    Bleiberg, H.2    Labianca, R.3
  • 45
    • 70449105423 scopus 로고    scopus 로고
    • A randomized phase III study com-paring adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer
    • Ychou M, Hohenberger W, Thezenas S, et al. A randomized phase III study com-paring adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. Ann Oncol 2009; 20:1964-70.
    • (2009) Ann Oncol , vol.20 , pp. 1964-1970
    • Ychou, M.1    Hohenberger, W.2    Thezenas, S.3
  • 46
    • 85206955878 scopus 로고    scopus 로고
    • Neoadjuvant irinotecan (CPT-11) 5-fluo-rouracil (5-FU) and leucovorin (LV) for colorectal liver metastases: A means of selecting candidates for resection
    • January 26-28, 2006; San Francisco, CA. Abstract 194
    • Bathe OF, Ernst S, Sutherland F, et al. Neoadjuvant irinotecan (CPT-11), 5-fluo-rouracil (5-FU), and leucovorin (LV) for colorectal liver metastases: A means of selecting candidates for resection. Presented at: the American Society of Clinical Oncology: 2006 Gastrointestinal Cancers Symposium; January 26-28, 2006; San Francisco, CA. Abstract 194.
    • Presented At: The American Society of Clinical Oncology: 2006 Gastrointestinal Cancers Symposium
    • Bathe, O.F.1    Ernst, S.2    Sutherland, F.3
  • 47
    • 34548242252 scopus 로고    scopus 로고
    • Presurgical chemotherapy in patients being considered for liver resec-tion
    • Kemeny N. Presurgical chemotherapy in patients being considered for liver resec-tion. Oncologist 2007; 12:825-39.
    • (2007) Oncologist , vol.12 , pp. 825-839
    • Kemeny, N.1
  • 48
    • 0037267766 scopus 로고    scopus 로고
    • Importance of response to neoadjuvant chemotherapy in patients undergoing resection of synchronous colorectal liver metastases
    • discussion 116-7
    • Allen PJ, Kemeny N, Jarnagin W, et al. Importance of response to neoadjuvant chemotherapy in patients undergoing resection of synchronous colorectal liver metastases. J Gastrointest Surg 2003; 7:109, discussion 116-7.
    • (2003) J Gastrointest Surg , vol.7 , pp. 109
    • Allen, P.J.1    Kemeny, N.2    Jarnagin, W.3
  • 49
    • 67651227762 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy followed by hepatectomy for primarily resectable colorectal cancer liver metastases
    • Chiappa A, Bertani E, Makuuchi M, et al. Neoadjuvant chemotherapy followed by hepatectomy for primarily resectable colorectal cancer liver metastases. Hepato-gastroenterology 2009; 56:829-34.
    • (2009) Hepato-gastroenterology , vol.56 , pp. 829-834
    • Chiappa, A.1    Bertani, E.2    Makuuchi, M.3
  • 50
    • 42949130734 scopus 로고    scopus 로고
    • Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer
    • Gruenberger B, Tamandl D, Schueller J, et al. Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer. J Clin Oncol 2008; 26:1830-5.
    • (2008) J Clin Oncol , vol.26 , pp. 1830-1835
    • Gruenberger, B.1    Tamandl, D.2    Schueller, J.3
  • 51
    • 54449098950 scopus 로고    scopus 로고
    • Perioperative or adjuvant therapy for resectable colorectal hepatic metastasis
    • Petrelli NJ. Perioperative or adjuvant therapy for resectable colorectal hepatic metastasis. J Clin Oncol 2008; 26:4862-3.
    • (2008) J Clin Oncol , vol.26 , pp. 4862-4863
    • Petrelli, N.J.1
  • 52
    • 67349166959 scopus 로고    scopus 로고
    • Is there a survival benefit to neoadjuvant versus adjuvant chemotherapy combined with surgery for resectable colorectal liver metastases?
    • Lubezky N, Geva R, Shmueli E, et al. Is there a survival benefit to neoadjuvant versus adjuvant chemotherapy, combined with surgery for resectable colorectal liver metastases? World J Surg 2009; 33:1028-34.
    • (2009) World J Surg , vol.33 , pp. 1028-1034
    • Lubezky, N.1    Geva, R.2    Shmueli, E.3
  • 53
    • 9744226672 scopus 로고    scopus 로고
    • Tumor progression while on chemotherapy: A contraindication to liver resection for multiple colorectal metastases?
    • discussion 61-4
    • Adam R, Pascal G, Castaing D, et al. Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases? Ann Surg 2004; 240:1052-61, discussion 61-4.
    • (2004) Ann Surg , vol.240 , pp. 1052-1061
    • Adam, R.1    Pascal, G.2    Castaing, D.3
  • 54
    • 33748460684 scopus 로고    scopus 로고
    • Complete response of colorectal liver me-tastases after chemotherapy: Does it mean cure?
    • Benoist S, Brouquet A, Penna C, et al. Complete response of colorectal liver me-tastases after chemotherapy: does it mean cure? J Clin Oncol 2006; 24:3939-45.
    • (2006) J Clin Oncol , vol.24 , pp. 3939-3945
    • Benoist, S.1    Brouquet, A.2    Penna, C.3
  • 55
    • 38049076324 scopus 로고    scopus 로고
    • Colorectal liver metastases contract centrip-etally with a response to chemotherapy: A histomorphologic study
    • Ng JK, Urbanski SJ, Mangat N, et al. Colorectal liver metastases contract centrip-etally with a response to chemotherapy: a histomorphologic study. Cancer 2008; 112:362-71.
    • (2008) Cancer , vol.112 , pp. 362-371
    • Ng, J.K.1    Urbanski, S.J.2    Mangat, N.3
  • 56
    • 11144354740 scopus 로고    scopus 로고
    • Severe hepatic sinusoidal obstruc-tion associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer
    • Rubbia-Brandt L, Audard V, Sartoretti P, et al. Severe hepatic sinusoidal obstruc-tion associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Ann Oncol 2004; 15:460-6.
    • (2004) Ann Oncol , vol.15 , pp. 460-466
    • Rubbia-Brandt, L.1    Audard, V.2    Sartoretti, P.3
  • 57
    • 0347481231 scopus 로고    scopus 로고
    • Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy
    • Parikh AA, Gentner B, Wu TT, et al. Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy J Gastrointest Surg 2003; 7:1082-8.
    • (2003) J Gastrointest Surg , vol.7 , pp. 1082-1088
    • Parikh, A.A.1    Gentner, B.2    Wu, T.T.3
  • 58
    • 33646457231 scopus 로고    scopus 로고
    • Chemotherapy regimen predicts steato-hepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases
    • Vauthey JN, Pawlik TM, Ribero D, et al. Chemotherapy regimen predicts steato-hepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol 2006; 24:2065-72.
    • (2006) J Clin Oncol , vol.24 , pp. 2065-2072
    • Vauthey, J.N.1    Pawlik, T.M.2    Ribero, D.3
  • 59
    • 33750957147 scopus 로고    scopus 로고
    • Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases
    • Aloia T, Sebagh M, Plasse M, et al. Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases. J Clin Oncol 2006; 24:4983-90.
    • (2006) J Clin Oncol , vol.24 , pp. 4983-4990
    • Aloia, T.1    Sebagh, M.2    Plasse, M.3
  • 61
    • 37549068554 scopus 로고    scopus 로고
    • Sinusoidal injury increases morbidity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy
    • Nakano H, Oussoultzoglou E, Rosso E, et al. Sinusoidal injury increases morbid-ity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy. Ann Surg 2008; 247:118-24.
    • (2008) Ann Surg , vol.247 , pp. 118-124
    • Nakano, H.1    Oussoultzoglou, E.2    Rosso, E.3
  • 62
    • 77951117267 scopus 로고    scopus 로고
    • Effect of extended preoperative chemotherapy on pathologic response and postoperative liver insufficiency after hepatic resec-tion for colorectal liver metastases
    • January 15-17, 2009; San Francisco, CA. Abstract 295
    • Zorzi D, Kishi Y, Maru DM, et al. Effect of extended preoperative chemotherapy on pathologic response and postoperative liver insufficiency after hepatic resec-tion for colorectal liver metastases. Presented at: the American Society of Clinical Oncology: 2009 Gastrointestinal Cancers Symposium; January 15-17, 2009; San Francisco, CA. Abstract 295.
    • Presented At: The American Society of Clinical Oncology: 2009 Gastrointestinal Cancers Symposium
    • Zorzi, D.1    Kishi, Y.2    Maru, D.M.3
  • 63
    • 68949219731 scopus 로고    scopus 로고
    • Outcome of initially unresectable metastatic colorectal cancer (MCRC) patients treated with first-line FOLFOXIRI followed by R0 surgical resection of metastases
    • abstract 4074
    • Masi G, Loupakis F, Fornaro L, et al. Outcome of initially unresectable metastatic colorectal cancer (MCRC) patients treated with first-line FOLFOXIRI followed by R0 surgical resection of metastases. J Clin Oncol 2008; 26(15 suppl):196s (abstract 4074).
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL.
    • Masi, G.1    Loupakis, F.2    Fornaro, L.3
  • 64
    • 58549090953 scopus 로고    scopus 로고
    • Preoperative chemotherapy does not increase morbidity or mortality of hepatic resection for colorectal cancer me-tastases
    • Scoggins CR, Campbell ML, Landry CS, et al. Preoperative chemotherapy does not increase morbidity or mortality of hepatic resection for colorectal cancer me-tastases. Ann Surg Oncol 2009; 16:35-41.
    • (2009) Ann Surg Oncol , vol.16 , pp. 35-41
    • Scoggins, C.R.1    Campbell, M.L.2    Landry, C.S.3
  • 65
    • 34247262529 scopus 로고    scopus 로고
    • Safe liver resection following chemotherapy for colorectal metastases is a matter of timing
    • Welsh FK, Tilney HS, Tekkis PP, et al. Safe liver resection following chemotherapy for colorectal metastases is a matter of timing. Br J Cancer 2007; 96:1037-42.
    • (2007) Br J Cancer , vol.96 , pp. 1037-1042
    • Welsh, F.K.1    Tilney, H.S.2    Tekkis, P.P.3
  • 66
    • 62349101530 scopus 로고    scopus 로고
    • Risk factors for chemotherapy-associated liver injuries: A multivariate analysis of a group of 146 patients with colorectal metastases
    • Brouquet A, Benoist S, Julie C, et al. Risk factors for chemotherapy-associated liver injuries: A multivariate analysis of a group of 146 patients with colorectal metastases. Surgery 2009; 145:362-71.
    • (2009) Surgery , vol.145 , pp. 362-371
    • Brouquet, A.1    Benoist, S.2    Julie, C.3
  • 67
    • 33644824747 scopus 로고    scopus 로고
    • Improving long-term outcomes for patients with liver metastases from colorectal cancer
    • Chong G, Cunningham D. Improving long-term outcomes for patients with liver metastases from colorectal cancer. J Clin Oncol 2005; 23:9063-6.
    • (2005) J Clin Oncol , vol.23 , pp. 9063-9066
    • Chong, G.1    Cunningham, D.2
  • 68
    • 34547183376 scopus 로고    scopus 로고
    • VEGF: A key therapeutic target for the treatment of cancer-insights into its role and pharmacological inhibition
    • Tobelem G. VEGF: A key therapeutic target for the treatment of cancer-insights into its role and pharmacological inhibition. Targeted Oncology 2007; 2:153-64
    • (2007) Targeted Oncology , vol.2 , pp. 153-164
    • Tobelem, G.1
  • 69
    • 33846603686 scopus 로고    scopus 로고
    • Lack of evidence for increased operative morbidity after hepatectomy with perioperative use of bevacizumab: A matched case-control study
    • D'Angelica M, Kornprat P, Gonen M, et al. Lack of evidence for increased operative morbidity after hepatectomy with perioperative use of bevacizumab: a matched case-control study. Ann Surg Oncol 2007; 14:759-65.
    • (2007) Ann Surg Oncol , vol.14 , pp. 759-765
    • D'Angelica, M.1    Kornprat, P.2    Gonen, M.3
  • 70
    • 85206956202 scopus 로고    scopus 로고
    • Efficacy and safety of bevacizumab with standard first-line fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer: FIRST BEAT
    • abstract O-029
    • Rivera F, Cunningham D, Berry S, et al. Efficacy and safety of bevacizumab with standard first-line fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer: FIRST BEAT Ann Oncol 2008; 19(suppl 6):vi17 (abstract O-029).
    • (2008) Ann Oncol , vol.19 , Issue.SUPPL. 6
    • Rivera, F.1    Cunningham, D.2    Berry, S.3
  • 71
    • 55949084563 scopus 로고    scopus 로고
    • Preoperative bevacizumab does not sig-nificantly increase postoperative complication rates in patients undergoing hepatic surgery for colorectal cancer liver metastases
    • Kesmodel SB, Ellis LM, Lin E, et al. Preoperative bevacizumab does not sig-nificantly increase postoperative complication rates in patients undergoing hepatic surgery for colorectal cancer liver metastases. J Clin Oncol 2008; 26:5254-60.
    • (2008) J Clin Oncol , vol.26 , pp. 5254-5260
    • Kesmodel, S.B.1    Ellis, L.M.2    Lin, E.3
  • 72
    • 66149155832 scopus 로고    scopus 로고
    • Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: Recommendations from an expert panel
    • Nordlinger B, Van Cutsem E, Gruenberger T, et al. Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: recommendations from an expert panel. Ann Oncol 2009; 20:985-92.
    • (2009) Ann Oncol , vol.20 , pp. 985-992
    • Nordlinger, B.1    Van Cutsem, E.2    Gruenberger, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.