Progesterone reduces the inhibitory effect of a serotonin 1B receptor agonist on lordosis behavior

Pharmacology Biochemistry and Behavior

Volumn 97, Issue 2, 2010, Pages 317-324

  Uphouse, Lynda ^a,b   Guptarak, Jutatip ^a   Hiegel, Cindy ^a  

^a TEXAS WOMAN'S UNIVERSITY   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

CP 93129; Hormonal priming; Hypothalamus; Intracranial infusion; Ovariectomized rats; Sexual behavior; Stress; Ventromedial nucleus

Indexed keywords

3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; ESTRADIOL BENZOATE; PROGESTERONE; SEROTONIN 1B RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; LORDOSIS; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SEXUAL BEHAVIOR; STRESS;

ANIMALS; ESTRADIOL; FEMALE; HANDLING (PSYCHOLOGY); MICROINJECTIONS; OVARIECTOMY; POSTURE; PROGESTERONE; PYRIDINES; PYRROLES; RATS; RATS, INBRED F344; RECEPTOR, SEROTONIN, 5-HT1B; SEROTONIN RECEPTOR AGONISTS; SEXUAL BEHAVIOR, ANIMAL; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

RATTUS; SESAMUM INDICUM;

EID: 77957792955     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2010.08.017     Document Type: Article

References (70)

1. Aiello-Zaldivar M., Luine V., Frankfurt M. 5, 7-DHT facilitated lordosis: effects of 5-HT agonists. NeuroReport 1992, 3:542-544.
2. Alex K.D., Pehek E.A. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacol Ther 2007, 113:296-320.
3. Armario A., Gavalda A., Marti J. Comparison of the behavioural and endocrine response to forced swimming stress in five inbred strains of rats. Psychoneuroendocrinology 1995, 20:879-890.
4. Auerbach S.B., Rutter J.J., Juliano P.J. Substituted piperazine and indole compounds increase extracellular serotonin in rat diencephalon as determined by in vivo microdialysis. Neuropharmacology 1991, 30:307-311.
5. Barnes N.M., Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 1999, 38:1083-1152.
6. Beekman M., Flachskamm C., Linthorst A.C. Effects of exposure to a predator on behaviour and serotonergic neurotransmission in different brain regions of C57bl/6N mice. Eur J Neurosci 2005, 21:2825-2836.
7. Bethea C.L., Lu N.Z., Gundlah C., Streicher J.M. Diverse actions of ovarian steroids in the serotonin neural system. Front Neuroendocrinol 2002, 23:41-100.
8. Blaustein J.D. Neuroendocrine regulation of feminine sexual behavior: lessons from rodent models and thoughts about humans. Annu Rev Psychol 2008, 59:93-118.
9. Blundell J.E., Lawton C.L., Halford J.C. Serotonin, eating behavior, and fat intake. Obes Res 1995, 3(Suppl 4):471S-476S.
10. Cecconello A.L., Raineki C., Sebben V., Lucion A.B., Sanvitto G.L. Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system. Behav Brain Res 2009, 207(2):429-433.
11. Dhabhar F.S., McEwen B.S., Spencer R.L. Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels-a comparison between Sprague-Dawley, Fischer 344 and Lewis rats. Brain Res 1993, 616:89-98.
12. Dhabhar F.S., Miller A.H., McEwen B.S., Spencer R.L. Differential activation of adrenal steroid receptors in neural and immune tissues of Sprague Dawley, Fischer 344, and Lewis rats. J Neuroimmunol 1995, 56:77-90.
13. Donadio M.V., Kunrath A., Corezola K.L., Franci C.R., Anselmo-Franci J.A., Lucion A.B., et al. Effects of acute stress on the day of proestrus on sexual behavior and ovulation in female rats: participation of the angiotensinergic system. Physiol Behav 2007, 92:591-600.
14. Engel G., Gothert M., Hoyer D., Schlicker E., Hillenbrand K. Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites. Naunyn Schmiedebergs Arch Pharmacol 1986, 332:1-7.
15. Erskine M.S. Solicitation behavior in the estrous female rat: a review. Horm Behav 1989, 23:473-502.
16. Farmer C.J., Isakson T.R., Coy D.J., Renner K.J. In vivo evidence for progesterone dependent decreases in serotonin release in the hypothalamus and midbrain central grey: relation to the induction of lordosis. Brain Res 1996, 711:84-92.
17. Foreman M.M., Moss R.L. Role of hypothalamic serotonergic receptors in the control of lordosis behavior in the female rat. Horm Behav 1978, 10:97-106.
18. Frye C.A. Progestins influence motivation, reward, conditioning, stress, and/or response to drugs of abuse. Pharmacol Biochem Behav 2007, 86:209-219.
19. Frye C.A., Petralia S.M., Rhodes M.E. Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha, 5alpha-THP. Pharmacol Biochem Behav 2000, 67:587-596.
20. Fujino K., Yoshitake T., Inoue O., Ibii N., Kehr J., Ishida J., et al. Increased serotonin release in mice frontal cortex and hippocampus induced by acute physiological stressors. Neurosci Lett 2002, 320:91-95.
21. Georgescu M., Pfaus J.G. Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors. II. Behavioral effects of selective glutamate receptor antagonists AP-5, CNQX, and DNQX. Pharmacol Biochem Behav 2006, 83:333-341.
22. Gomez-Serrano M.A., Kearns D.N., Riley A.L. The effects of light cycle phase on morphine-induced conditioned taste aversions in the Lewis, Fischer and Sprague-Dawley rat strains. Behav Brain Res 2009, 196:116-122.
23. Gorzalka B.B., Hanson L.A., Brotto L.A. Chronic stress effects on sexual behavior in male and female rats: mediation by 5-HT2A receptors. Pharmacol Biochem Behav 1998, 61:405-412.
24. Guptarak J., Selvamani A., Uphouse L. GABAA-5-HT1A receptor interaction in the mediobasal hypothalamus. Brain Res 2004, 1027:144-150.
25. Hannon J., Hoyer D. Molecular biology of 5-HT receptors. Behav Brain Res 2008, 195:198-213.
26. Hjorth S., Tao R. The putative 5-HT1B receptor agonist CP-93, 129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969. Eur J Pharmacol 1991, 209:249-252.
27. Hulse G.K., Coleman G.J. The role of endogenous opioids in the blockade of reproductive function in the rat following exposure to acute stress. Pharmacol Biochem Behav 1983, 19:795-799.
28. Izumi J., Washizuka M., Hayashi-Kuwabara Y., Yoshinaga K., Tanaka Y., Ikeda Y., et al. An attenuated alpha-1 potentiation of beta adrenoceptor-stimulated cyclic AMP formation after repeated saline injections in Fischer 344 strain rats. Life Sci 1996, 59:33-42.
29. Jackson A., Uphouse L. Dose-dependent effects of estradiol benzoate on 5-HT1A receptor agonist action. Brain Res 1998, 796:299-302.
30. Jonnakuty C., Gragnoli C. What do we know about serotonin?. J Cell Physiol 2008, 217:301-306.
31. Kirby L.G., Chou-Green J.M., Davis K., Lucki I. The effects of different stressors on extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid. Brain Res 1997, 760:218-230.
32. König J., Klippel R. The rat brain. A Stereotaxic Atlas of the Forebrain and Lower Parts of the Brain Stem 1963, Williams and Wilkins, Baltimore.
33. Llaneza D.C., Frye C.A. Progestogens and estrogen influence impulsive burying and avoidant freezing behavior of naturally cycling and ovariectomized rats. Pharmacol Biochem Behav 2009, 93:337-342.
34. Mani S.K. Signaling mechanisms in progesterone-neurotransmitter interactions. Neuroscience 2006, 138:773-781.
35. Mani S.K., Blaustein J.D., Allen J.M., Law S.W., O'Malley B.W., Clark J.H. Inhibition of rat sexual behavior by antisense oligonucleotides to the progesterone receptor. Endocrinology 1994, 135:1409-1414.
36. Mani S.K., Allen J.M., Lydon J.P., Mulac-Jericevic B., Blaustein J.D., DeMayo F.J., et al. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice. Mol Endocrinol 1996, 10:1728-1737.
37. Marcondes F.K., Miguel K.J., Melo L.L., Spadari-Bratfisch R.C. Estrous cycle influences the response of female rats in the elevated plus-maze test. Physiol Behav 2001, 74:435-440.
38. Marissal-Arvy N., Gaumont A., Langlois A., Dabertrand F., Bouchecareilh M., Tridon C., et al. Strain differences in hypothalamic pituitary adrenocortical axis function and adipogenic effects of corticosterone in rats. J Endocrinol 2007, 195:473-484.
39. Maswood S., Andrade M., Caldarola-Pastuszka M., Uphouse L. Protective actions of the 5-HT2A/2C receptor agonist, DOI, on 5-HT1A receptor-mediated inhibition of lordosis behavior. Neuropharmacology 1996, 35:497-501.
40. Maswood N., Caldarola-Pastuszka M., Uphouse L. 5-HT3 receptors in the ventromedial nucleus of the hypothalamus and female sexual behavior. Brain Res 1997, 769:13-20.
41. Maswood N., Caldarola-Pastuszka M., Uphouse L. Functional integration among 5-hydroxytryptamine receptor families in the control of female rat sexual behavior. Brain Res 1998, 802:98-103.
42. Maswood S., Truitt W., Hotema M., Caldarola-Pastuszka M., Uphouse L. Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: role of the serotonin transporter and terminal autoreceptors. Brain Res 1999, 831:146-154.
43. McCarthy M.M., Felzenberg E., Robbins A., Pfaff D.W., Schwartz-Giblin S. Infusions of diazepam and allopregnanolone into the midbrain central gray facilitate open-field behavior and sexual receptivity in female rats. Horm Behav 1995, 29:279-295.
44. Mendelson S.D. A review and reevaluation of the role of serotonin in the modulation of lordosis behavior in the female rat. Neurosci Biobehav Rev 1992, 16:309-350.
45. Mendelson S.D., Gorzalka B.B. Sex differences in the effects of 1-(m-trifluoromethylphenyl) piperazine and 1-(m-chlorophenyl) piperazine on copulatory behavior in the rat. Neuropharmacology 1990, 29:783-786.
46. Mo B., Feng N., Renner K., Forster G. Restraint stress increases serotonin release in the central nucleus of the amygdala via activation of corticotropin-releasing factor receptors. Brain Res Bull 2008, 76:493-498.
47. Ogawa S., Olazabal U.E., Parhar I.S., Pfaff D.W. Effects of intrahypothalamic administration of antisense DNA for progesterone receptor mRNA on reproductive behavior and progesterone receptor immunoreactivity in female rat. J Neurosci 1994, 14:1766-1774.
48. Pfaff D.W., Kow L.M., Loose M.D., Flanagan-Cato L.M. Reverse engineering the lordosis behavior circuit. Horm Behav 2008, 54:347-354.
49. Picazo O., Fernandez-Guasti A. Anti-anxiety effects of progesterone and some of its reduced metabolites: an evaluation using the burying behavior test. Brain Res 1995, 680:135-141.
50. Rosecrans J.A., Robinson S.E., Johnson J.H., Mokler D.J., Hong J.S. Neuroendocrine, biogenic amine and behavioral responsiveness to a repeated foot-shock-induced analgesia (FSIA) stressor in Sprague-Dawley (CD) and Fischer-344 (CDF) rats. Brain Res 1986, 382:71-80.
51. Saavedra M., Contreras C.M., Azamar-Arizmendi G., Hernandez-Lozano M. Differential progesterone effects on defensive burying and forced swimming tests depending upon a gradual decrease or an abrupt suppression schedules. Pharmacol Biochem Behav 2006, 83:130-135.
52. Sarrieau A., Mormede P. Hypothalamic-pituitary-adrenal axis activity in the inbred Brown Norway and Fischer 344 rat strains. Life Sci 1998, 62:1417-1425.
53. Schneider T., Popik P. Attenuation of estrous cycle-dependent marble burying in female rats by acute treatment with progesterone and antidepressants. Psychoneuroendocrinology 2007, 32:651-659.
54. Shimizu N., Take S., Hori T., Oomura Y. In vivo measurement of hypothalamic serotonin release by intracerebral microdialysis: significant enhancement by immobilization stress in rats. Brain Res Bull 1992, 28:727-734.
55. Siddiqui A., Abu-Amara M., Aldairy C., Hagan J.J., Wilson C. 5-HT7 receptor subtype as a mediator of the serotonergic regulation of luteinizing hormone release in the zona incerta. Eur J Pharmacol 2004, 491:77-84.
56. Siddiqui A., Niazi A., Shaharyar S., Wilson C.A. The 5HT(7) receptor subtype is involved in the regulation of female sexual behaviour in the rat. Pharmacol Biochem Behav 2007, 87:386-392.
57. Sinclair-Worley L., Uphouse L. Effect of estrogen on the lordosis-inhibiting action of ketanserin and SB 206553. Behav Brain Res 2004, 152:129-135.
58. Sodersten P. Estradiol-progesterone interactions in the reproductive behavior of female rats. Current Topics in Neuroendocrinology: Actions of Progesterone on the Brain 1981, 141-174. Springer-Verlag, New York. D. Ganten, D. Pfaff (Eds.).
59. Stohr T., Szuran T., Welzl H., Pliska V., Feldon J., Pryce C.R. Lewis/Fischer rat strain differences in endocrine and behavioural responses to environmental challenge. Pharmacol Biochem Behav 2000, 67:809-819.
60. Tanco S.A., Watson N.V., Gorzalka B.B. Lack of effects of 5-HT3 antagonists on normal and morphine-attenuated sexual behaviours in female and male rats. Experientia 1993, 49:238-241.
61. Truitt W., Harrison L., Guptarak J., White S., Hiegel C., Uphouse L. Progesterone attenuates the effect of the 5-HT1A receptor agonist, 8-OH-DPAT, and of mild restraint on lordosis behavior. Brain Res 2003, 974:202-211.
62. Uphouse L. Female gonadal hormones, serotonin, and sexual receptivity. Brain Res Brain Res Rev 2000, 33:242-257.
63. Uphouse L., Caldarola-Pastuszka M., Montanez S. Intracerebral actions of the 5-HT1A agonists, 8-OH-DPAT and buspirone and of the 5-HT1A partial agonist/antagonist, NAN-190, on female sexual behavior. Neuropharmacology 1992, 31:969-981.
64. Uphouse L., White S., Harrison L., Hiegel C., Majumdar D., Guptarak J., et al. Restraint accentuates the effects of 5-HT2 receptor antagonists and a 5-HT1A receptor agonist on lordosis behavior. Pharmacol Biochem Behav 2003, 76:63-73.
65. Uphouse L., Selvamani A., Lincoln C., Morales L., Comeaux D. Mild restraint reduces the time hormonally primed rats spend with sexually active males. Behav Brain Res 2005, 157:343-350.
66. Uphouse L., Hiegel C., Perez E., Guptarak J. Serotonin receptor involvement in effects of restraint on female rat lordosis behavior. Pharmacol Biochem Behav 2007, 86:631-636.
67. Uphouse L., Hiegel C., Sarkar J., Hurlburt J., Templeton C., Guptarak J., et al. Female gonadal hormones, mild restraint, and male preference. Pharmacol Biochem Behav 2008, 90:758-762.
68. Uphouse L., Hiegel C., Guptarak J., Maswood N. Progesterone reduces the effect of the serotonin 1B/1D receptor antagonist, GR 127935, on lordosis behavior. Horm Behav 2009, 55:169-174.
69. White S., Uphouse L. Estrogen and progesterone dose-dependently reduce disruptive effects of restraint on lordosis behavior. Horm Behav 2004, 45:201-208.
70. Zar J. Biostatistical Analysis 1999, Prentice Hall, Englewood Cliffs, NJ.