Polymorphisms of the hypoxia-inducible factor 1 gene and peripheral artery disease

Vascular Medicine

Volumn 15, Issue 5, 2010, Pages 371-374

  Bahadori, Babak ^a   Uitz, Elisabeth ^a   Mayer, Andreas ^a   ̈rgenHarauer, Ju ^a   Dam, Karl ^a   Truschnig Wilders, Martini ^b   Pilger, Ernst ^b   Renner, Wilfried ^b  

^a State Clinic St Poelten   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

genetics; hypoxia inducible factor 1; peripheral artery disease; polymorphism

Indexed keywords

EXONUCLEASE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ADULT; AGED; ANKLE BRACHIAL INDEX; ARTERY DISEASE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; SMOKING;

ADULT; AGED; AUSTRIA; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PERIPHERAL ARTERIAL DISEASE; PHENOTYPE; POLYMORPHISM, GENETIC; RISK ASSESSMENT; RISK FACTORS;

EID: 77957791211     PISSN: 1358863X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1358863X10379674     Document Type: Article

References (21)

1. Haugen S, Casserly IP, Regensteiner JG, Hiatt WR. Risk assessment in the patient with established peripheral arterial disease. Vasc Med 2007; 12: 343-350.
2. Minar E. Peripheral arterial occlusive disease. Vasa 2007; 36: 155-164.
3. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999; 340: 115-126.
4. Kullo IJ, Turner ST, Kardia SL, Mosley TH Jr, Boerwinkle E, Andrade MD. A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study. Atherosclerosis 2006; 187: 433-438.
5. Murabito JM, Guo CY, Fox CS, D'Agostino RB. Heritability of the ankle-brachial index: the Framingham Offspring study. Am J Epidemiol 2006; 164: 963-968.
6. Knowles JW, Assimes TL, Li J, Quertermous T, Cooke JP. Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology. Arterioscler Thromb Vasc Biol 2007; 27: 2068-2078.
7. Ho TK, Abraham DJ, Black CM, Baker DM. Hypoxia-inducible factor 1 in lower limb ischemia. Vascular 2006; 14: 321-327.
8. Vink A, Schoneveld AH, Lamers D, et al. HIF-1 alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages. Atherosclerosis 2007; 195: e69-75.
9. Tanimoto K, Yoshiga K, Eguchi H, et al. Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance. Carcinogenesis 2003; 24: 1779-1783.
10. Resar JR, Roguin A, Voner J, et al Hypoxia-inducible factor 1alpha polymorphism and coronary collaterals in patients with ischemic heart disease. Chest 2005; 128: 787-791.
11. Hlatky MA, Quertermous T, Boothroyd DB, et al. Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease. Am Heart J 2007; 154: 1035-1042.
12. Halperin JL, Creage MA. Arterial obstructive disease of the extremities. In: Loscalzo J, Creager MA, Dzau VJ (eds). Vascular medicine. Boston: Little, Brown and Company, 1996, p.825-852.
13. Sanchez LA, Veith FJ. Diagnosis and treatment of chronic lower extremity ischemia. Vasc Med 1998; 3: 291-299.
14. Alberti KGMM, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications part 1: diagnosis and classification of diabetes mellitus-provisional report of a WHO consultation. Diabet Med 1998; 15: 539-553.
15. Apaydin I, Konac E, Onen HI, Akbaba M, Tekin E, Ekmekci A. Single nucleotide polymorphisms in the hypoxia-induc-ible factor-1alpha (HIF-1alpha) gene in human sporadic breast cancer. Arch Med Res 2008; 39: 338-345.
16. Lee JY, Choi JY, Lee KM, et al. Rare variant of hypoxia-inducible factor-1alpha (HIF-1A) and breast cancer risk in Korean women. Clin Chim Acta 2008; 389: 167-170.
17. Konac E, Onen HI, Metindir J, Alp E, Biri AA, Ekmekci A. An investigation of relationships between hypoxia-inducible factor-1 alpha gene polymorphisms and ovarian, cervical and endometrial cancers. Cancer Detect Prev 2007; 31: 102-109.
18. Hong JM, Kim TH, Chae SC, et al. Association study of hypoxia inducible factor 1alpha (HIF1alpha) with osteonecrosis of femoral head in a Korean population. Osteoarthritis Cartilage 2007; 15: 688-694.
19. Koukourakis MI, Papazoglou D, Giatromanolaki A, et al. C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1alpha gene define HIF-1alpha protein expression in non-small cell lung cancer. Lung Cancer 2006; 53: 257-262.
20. Yamada N, Horikawa Y, Oda N, et al. Genetic variation in the hypoxia-inducible factor-1alpha gene is associated with type 2 diabetes in Japanese. J Clin Endocrinol Metab 2005; 90: 5841-5847. (Pubitemid 41415501)
21. Rajagopalan S, Olin J, Deitcher S, et al. Use of a constitu-tively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: phase I dose-escalation experience. Circulation 2007; 115: 1234-1243.