Computer-aided design of novel inhibitors of human leukocyte elastase

Pharmacochemistry Library

Volumn 28, Issue C, 1997, Pages 499-509

  Andisik, D ^a   Bernstein, P ^a   Brown, F ^a   Bryant, C ^a   Ceccarelli, C ^a   Damewood, J ^a   Edwards, P ^a   Feeney, S ^a   Gomes, B ^a   Green, R ^a   Kosmider, B ^a   Shaw, A ^a   Steelman, G ^a   Thomas, R ^a   Tuthill, P ^a   Vacek, E ^a   Veale, C ^a   Warner, P ^a   Williams, J ^a   Wolanin, D ^a   Woolson, S ^a   more..

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77957776948     PISSN: 01657208     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0165-7208(97)80090-6     Document Type: Article

References (32)

1. Travis J., Dublin A., Potempa J., Watorek W., and Kurdowska A. Ann. N. Y. Acad. Sci. 624 (1991) 81-86
2. Janoff A. Am. Rev. Respir. Dis. 132 (1985) 417-433
3. Erisson S. Eur. Respir. J. 4 (1991) 1041-1043
4. Snider G.L., Ciccolella D.E., Morris S.M., Stone P.J., and Lucey E.C. Ann. N. Y. Acad. Sci. 624 (1991) 45-59
5. Merritt T.A., Cochrane C.G., Holcomb K., Bohl B., Hallman M., Strayer D., and Edwards D. J. Clin. Invest. 72 (1983) 656-666
6. Petty T.L. Ann. N. Y. Acad. Sci. 624 (1991) 267-277
7. Nadel J.A. Am Rev. Respir. Dis. 144 (1991) S48-S51
8. Jackson A.H., Hill S.L., Afford S.C., and Stockley R.A. J. Respir. Dis. 65 (1984) 114-124
9. Nadel J.A. Ann. N. Y. Acad. Sci. 624 (1991) 286-296
10. Stockley R.A., Hill S.L., and Burnett D. Ann. N. Y. Acad. Sci. 624 (1991) 257-266
11. Turino G.M. Ann. N. Y. Acad. Sci. 624 (1991) 18-29
12. Travis J., and Johnson D. J. Biol Chem. 253 (1978) 7142-7144
13. Beatty K., Matteson N., and Travis J. Hoppe-Segler's Z. Physiol. Chem. 365 (1984) 731-736
14. and references therein. Edwards P.D., and Bernstein P.R. Med. Res. Rev. 14 (1994) 127-194
15. Takahashi L.H., Radhakrishnan R., Rosenfield R.E., Meyers E.F., Trainor D.A., and Stein M. J.Mol. Biol. 201 (1988) 423-428
16. Williams J.C., Falcone R.C., Knee C., Stein R.L., Strimpler A.M., Reaves B., Giles R.E., and Krell R.D. Am. Rev. Respir. Dis. 144 (1991) 875-883
17. Williams J.C., Stein R.L., Giles R.E., and Krell R.D. Ann. N. Y. Acad. Sci. 624 (1991) 230-243
18. Bode W., Wei A.-Z., Huber R., Meyer E., Travis J., and Neumann S. EMBO J. 5 (1986) 2453-2458
19. Bode W., Meyer E., and Powers J.C. Biochemistry 28 (1989) 1951-1963
20. Skiles J.W., Fuchs V., Miao C., Sorcek R., Grozinger K.G., Maudlin S.C., Vitous J., Mui P.W., Jacober S., Chow G., Matteo M., Skoog M., Weldon S., Pssanza G., Keirns J., Letts G., and Rosenthal A.S. J. Med. Chem. 35 (1992) 641-662
21. Skiles J.W., Miao C., Sorcek R., Maudlin S.C., Mui P.W., Jacober S., Chow G., Skoog M.W.S., Possanza G., Keirns J., Letts G., and Rosenthal A.S. J. Med. Chem. 35 (1992) 4795-4808
22. DJ Wolanin, personal communication.
23. Skiles J.W., Sorcek R., Jacober S., Miao C., Mui C., Mui P.W., McNeil D., and Rosenthal A.S. Bioorg, Med. Chem. Letts 3 (1993) 773-778
24. Warner P., Green R.C., Gomes B., and Strimpler A.M. J. Med. Chem. 37 (1994) 3090-3099
25. Brown F.J., Andisik D.W., Bernstein P.R., Bryant C.B., Ceccarelli C., Damewood J.R., Edwards P.D., Earley R.A., Feeney S., Green R.C., Gomes B., Kosmider B.J., Krell R.D., Shaw A., Steelman G.B., Thomas R.M., Vacek E.P., Veale C.A., Tuthill P.A., Warner P., Williams J.C., Wolanin D.J., and Wooson S.A. J. Med Chem. 37 (1994) 1259-1261
26. Damewood J.R., Edwards P.D., Feeney S., Gomes B.C., Steelma G.B., Tuthill P.A., Williams J.C., Woolson S.A., Wolanin D.J., and Veale C.A. J. Med. Chem. 37 (1994) 3303-3312
27. Bernstein P.R., Andisik D., Bradley P.K., Bryant C.B., Ceccarelli C., Damewood J.R., Earley R., Edwards P.D., Feeney S., Gomes B.C., Kosmider B.J., Steelman G.B., Thomas R.M., Vacek E.P., Veale C.A., Williams J.C., Wolanin D.J., and Woolson S.A. J. Med. Chem. 37 (1994) 3313-3326
28. Edwards P.D., Andisik D.W., Strimpler A.M., Gomes B., and Tuthill P.A. J. Med. Chem. 39 (1996) 1112-1124
29. Veale C.A., Damewood J.R., Steelman G.B., Bryant C., Gomes B., and Williams J. J. Med. Chem. 38 (1995) 86-97
30. Veale C.A., Bernstein P.R., Bryant C., Ceccarelli C., Damewood J.R., Earley R., Feeney S.W., Gomes B., Kosmider B.J., Steelman G.B., Thomas R.M., Vacek E.P., Williams J.C., Wolanin D.J., and Woolson S. J. Med. Chem. 38 (1995) 98-108
31. World patent application WO 9618644. Tamura SY, Semple JE, Ripka WC, Ardecky R.J.
32. Dolle R.E., Prouty C.P., Prasad C.V.C., Cook E., Saha A., Morgan R.T., Salvino J.M., Helaszek C.T., and Ator M.A. J. Med. Chem. 39 (1996) 2438-2440