IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist

Journal of Allergy and Clinical Immunology

Volumn 126, Issue 4, 2010, Pages 875-878

  Slager, Rebecca E ^a   Hawkins, Gregory A ^a   Ampleford, Elizabeth J ^a   Bowden, Alexandra ^b   Stevens, Lauren E ^b   Morton, Matthew T ^b   Tomkinson, Adrian ^b   Wenzel, Sally E ^c   Longphre, Malinda ^b   Bleecker, Eugene R ^a   Meyers, Deborah A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b Aerovance   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR ANTAGONIST; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; PITRAKINRA; PLACEBO; STAT6 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ASTHMA; CLINICAL TRIAL; DNA SEQUENCE; DRUG MECHANISM; EOSINOPHIL COUNT; FORCED EXPIRATORY VOLUME; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; LETTER; LUNG FUNCTION; LUNG LAVAGE; NONHUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE;

EID: 77957764848     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.08.001     Document Type: Article

References (9)

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