Fantastic voyage and opportunities of engineered nanomaterials: What are the potential risks of occupational exposures?

Journal of Occupational and Environmental Medicine

Volumn 52, Issue 9, 2010, Pages 943-946

  Kagan, Valerian E ^a   Shi, Jingwen ^a,b   Feng, Weihong ^a   Shvedova, Anna A ^a,c,d   Fadeel, Bengt ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^d WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON NANOTUBE; COLLAGEN; MULTI WALLED NANOTUBE; NANOCAPSULE; NANOMATERIAL; SINGLE WALLED NANOTUBE;

ARTIFICIAL ORGAN; BIOENGINEERING; BIOMEDICINE; COLLAGEN SYNTHESIS; CONFOCAL MICROSCOPY; CYTOTOXICITY; ELECTRON MICROSCOPY; ENVIRONMENTAL EXPOSURE; HEALTH SURVEY; HUMAN; INFLAMMATION; LUNG INFECTION; NANOMEDICINE; NANOTECHNOLOGY; NONHUMAN; NOTE; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PLEURA EFFUSION;

ANIMALS; HUMANS; MICE; NANOSTRUCTURES; OCCUPATIONAL EXPOSURE; RISK ASSESSMENT;

EID: 77957759662     PISSN: 10762752     EISSN: None     Source Type: Journal    
DOI: 10.1097/JOM.0b013e3181dc6c52     Document Type: Note

References (16)

1. Fadeel B, Kasemo B, Malmsten M, Strømme M. Nanomedicine: reshaping clinical practice. JIntern Med. 2010;267:2-8.
2. Xia T, Li N, Nel AE. Potential health impact of nanoparticles. Annu Rev Public Health. 2009; 30:137-150.
3. Oberdörster G, Oberdörster E, Oberdörster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005;113:823-839.
4. Shvedova AA, Kagan VE, Fadeel B. Close encounters of the small kind: adverse effects of man-made materials interfacing with the nano-cosmos ofbiological systems. Annu Rev Pharmacol Toxicol. 2010;50:63-88.
5. Sargent LM, Shvedova AA, Hubbs AF, et al. Induction of aneuploidy by single-walled car-bon nanotubes. Environ Mol Mutagen. 2009; 50:708-717.
6. Kenne K, Ljungquist S, Ringertz NR. Effects of asbestos fibers on cell division, cell survival, and formation of thioguanine-resistant mutants in Chinese hamster ovary cells. Environ Res. 1986;39:448-464.
7. Schulte P, Geraci C, Zumwalde R, Hoover M, Kuempel E. Occupational risk management of engineered nanoparticles. J Occup Environ Hyg. 2008;5:239-249.
8. Song Y, Li X, Du X. Exposure to nanoparticles is related to pleural effusion, pulmonary fibro-sis andgranuloma. EurRespirJ. 2009;34:559-567.
9. Shvedova AA, Kisin E, Murray AR, et al. Inha-lation vs. aspiration ofsingle-walled carbon nano-tubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am J Physiol Lung Cell MolPhysiol. 2008;295:L552-L565.
10. Shvedova AA, Fabisiak JP, Kisin ER, et al. Sequen-tial exposure to carbon nanotubes and bacteria en-hances pulmonary inflammation and infectivity. Am JRespir Cell Mol Biol. 2008;38:579-590.
11. Yang ST, Wang X, Jia G, et al. Long-term accumulation and low toxicity ofsingle-walled carbon nanotubes in intravenously exposed mice. ToxicolLett. 2008;181:182-189.
12. Park JH, Gu L, von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ. Biodegradable lumines-cent porous silicon nanoparticles for in vivo applications. Nat Mater. 2009;8:331-336.
13. Allen BL, Kotchey GP, Chen Y, et al. Mechanis-tic investigations of horseradish peroxidase-cata-lyzed degradation of single-walled carbon nano-tubes. JAm Chem Soc. 2009;131:17194-17205.
14. Kagan VE, Konduru NV, Feng W, et al. Carbon nanotubes degraded by neutrophil myeloperox-idase induce less pulmonary inflammation. Na-ture Nanotechnology. 2010;5:354-359.
15. Gwinn MR, Tran L. Risk management ofnano-materials. WIREs Nanomed Nanobiotechnol. 2010;2:130-137.
16. Warheit DB, Sayes CM, Reed KL, Swain KA. Health effects related to nanoparticle exposures: environmental, health and safety considerations for assessing hazards and risks. Pharmacol Ther. 2008;120:35-42.