Remifentanil reduces the incidence of post-operative delirium

Journal of International Medical Research

Volumn 38, Issue 4, 2010, Pages 1225-1232

  Radtke, F M ^a   Franck, M ^a   Lorenz, M ^a   Luetz, A ^a   Heymann, A ^a   Wernecke, K D ^b   Spies, C D ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b SOSTANA GMBH   (Germany)

Author keywords

Analgesia; Delirium; Fentanyl; Intraoperative; Opioids; Outcome; Remifentanil

Indexed keywords

FENTANYL; REMIFENTANIL;

ADULT; ARTICLE; CONTROLLED STUDY; DELIRIUM; DISEASE ASSOCIATION; DRUG USE; FEMALE; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PATIENT MONITORING; POSTOPERATIVE PERIOD; RECOVERY ROOM; SCREENING TEST;

EID: 77957745095     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800403     Document Type: Article

References (32)

1. Dasgupta M, Dumbrell AC: Preoperative risk assessment for delirium after noncardiac surgery: a systematic review. J Am Geriatr Soc 2006; 54: 1578-1589.
2. Bickel H, Gradinger R, Kochs E, et al: High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study. Dement Geriatr Cogn Disord 2008; 26: 26-31.
3. de Jonghe JF, Kalisvaart KJ, Dijkstra M, et al: Early symptoms in the prodromal phase of delirium: a prospective cohort study in elderly patients undergoing hip surgery. Am J Geriatr Psychiatr 2007; 15: 112-121.
4. Wacker P, Nunes PV, Cabrita H, et al: Postoperative delirium is associated with poor cognitive outcome and dementia. Dement Geriatr Cogn Disord 2006; 21: 221-227.
5. Cavaliere F, D'Ambrosio F, Volpe C, et al: Postoperative delirium. Curr Drug Targets 2005; 6: 807-814.
6. Norkiene I, Ringaitiene D, Misiuriene I, et al: Incidence and precipitating factors of delirium after coronary bypass grafting. Scand Cardiovasc J 2007; 41: 180-185.
7. Thomason JW, Shintani A, Peterson JF, et al: Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients. Crit Care 2005; 9: R375-R331.
8. Inouye SK: Predisposing and precipitating factors for delirium in hospitalized older patients. Dement Geriatr Cogn Disord 1999; 10: 393-400.
9. Gaudreau JD, Gagnon P, Harel F, et al: Fast, systematic, and continuous delirium assessment in hospitalized patients: the Nursing Delirium Screening Scale. J Pain Symptom Manag 2005; 29: 368-375.
10. Gaudreau JD, Gagnon P, Harel F, et al: Psychoactive medications and risk of delirium in hospitalized cancer patients. J Clin Oncol 2005; 23: 6712-6718.
11. Radtke FM, Franck M, Macguill M, et al: Duration of fluid fasting and choice of analgesic are modifiable factors for early postoperative delirium. Eur J Anaesthesiol 2010; 27: 411-416.
12. American Society of Anesthesiologists (ASA): ASA Physical Status Classification System. Park Ridge: ASA (available at: http://www.asahq.org/clinical/physicalstatus.htm).
13. Lütz A, Radtke FM, Franck M, et al: The Nursing Delirium Screening Scale (Nu-DESC). Anastesiol Intensivmed Notfallmed Schmerzther 2008; 43: 98-102 [in German].
14. nd edn. Berlin: Springer, 2005 [in German].
15. Bruce AJ, Ritchie CW, Blizard R, et al: The incidence of delirium associated with orthopedic surgery: a meta-analytic review. Int Psychogeriatr 2007; 19: 197-214.
16. Marcantonio ER, Goldman L, Mangione CM, et al: A clinical prediction rule for delirium after elective noncardiac surgery. JAMA 1994; 271: 134-139.
17. Gaudreau JD, Gagnon P, Roy MA, et al: Opioid medications and longitudinal risk of delirium in hospitalized cancer patients. Cancer 2007; 109: 2365-2373.
18. Marcantonio ER, Juarez G, Goldman L, et al: The relationship of postoperative delirium with psychoactive medications. JAMA 1994; 272: 1518-1522.
19. Dubois MJ, Bergeron N, Dumont M, et al: Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 2001; 27: 1297-1304.
20. Fong HK, Sands LP, Leung JM: The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review. Anesth Analg 2006; 102: 1255-1266.
21. Kapila A, Glass PS, Jacobs JR, et al: Measured context-sensitive half-times of remifentanil and alfentanil. Anesthesiology 1995; 83: 968-975.
22. Egan TD: Remifentanil pharmacokinetics and pharmacodynamics. A preliminary appraisal. Clin Pharmacokinet 1995; 29: 80-94.
23. von Dossow, V, Luetz A, Haas A, et al: Effects of remifentanil and fentanyl on the cell-mediated immune response in patients undergoing elective coronary artery bypass graft surgery. J Int Med Res 2008; 36: 1235-1247.
24. Winterhalter M, Brandl K, Rahe-Meyer N, et al: Endocrine stress response and inflammatory activation during CABG surgery. A randomized trial comparing remifentanil infusion to intermittent fentanyl. Eur J Anaesthesiol 2008; 25: 326-335.
25. Maclullich AM, Ferguson KJ, Miller T, et al: Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses. J Psychosom Res 2008; 65: 229-238.
26. Kehlet H, Dahl JB: Anaesthesia, surgery, and challenges in postoperative recovery. Lancet 2003; 362: 1921-1928.
27. Böhner H, Friedrichs R, Habel U, et al: Delirium increases morbidity and length of stay after vascular surgery operations. Results of a prospective study. Chirurg 2003; 74: 931-936 [in German].
28. Inouye SK, Foreman MD, Mion LC, et al: Nurses' recognition of delirium and its symptoms: comparison of nurse and researcher ratings. Arch Intern Med 2001; 161: 2467-2473.
29. Peterson JF, Pun B-T, Dittus R-S, et al: Delirium and its motoric subtypes: a study of 614 critically ill patients. J Am Geriatr Soc 2006; 54: 479-484.
30. Radtke FM, Franck M, Schneider M, et al: Comparison of three scores to screen for delirium in the recovery room. Br J Anaesth 2008; 101: 338-343.
31. Ohki T, Matsushima E, Shibuya M, et al: An evaluation strategy for the early detection of postoperative delirium. Psychiatry Clin Neurosci 2006; 60: 277-282.
32. Robinson TN, Raeburn CD, Tran ZV, et al: Postoperative delirium in the elderly: risk factors and outcomes. Ann Surg 2009; 249: 173-178.