Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas

Leukemia and Lymphoma

Volumn 51, Issue 10, 2010, Pages 1875-1886

  Reiss, Cora ^a   Haneke, Torsten ^a   Völker, Hans Ulrich ^a   Spahn, Martin ^c   Rosenwald, Andreas ^a   Edelmann, Winfried ^b   Kneitz, Burkhard ^a,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Conditional mouse model; Lck Cre; Lymphoblastic T cell lymphoma; Mismatch repair; MLH1

Indexed keywords

CRE RECOMBINASE; PROTEIN MLH1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENE INACTIVATION; LYMPHOID PROGENITOR CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T CELL LYMPHOMA; T LYMPHOCYTE; THYMOCYTE; TRANSGENE; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA REPAIR; EXONS; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, LEUKEMIC; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSATELLITE INSTABILITY; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID; T-LYMPHOCYTES; THYMUS GLAND;

EID: 77957740256     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2010.510360     Document Type: Article

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