Antiviral treatment for severe EBV infections in apparently immunocompetent patients

Journal of Clinical Virology

Volumn 49, Issue 3, 2010, Pages 151-157

  Rafailidis, Petros I ^a,b   Mavros, Michael N ^a   Kapaskelis, Anastasios ^a,b   Falagas, Matthew E ^a,b,c  

^a ALFA INSTITUTE OF BIOMEDICAL SCIENCES AIBS   (Greece)

^b HENRY DUNANT HOSPITAL   (Greece)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acyclovir; Epstein Barr; Infectious mononucleosis

Indexed keywords

ACICLOVIR; ALPHA INTERFERON; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; DIURETIC AGENT; FAMCICLOVIR; FOSCARNET; GANCICLOVIR; GRANULOCYTE COLONY STIMULATING FACTOR; RIBAVIRIN; STEROID; THYMOCYTE ANTIBODY; VALACICLOVIR; VIDARABINE;

ACUTE KIDNEY FAILURE; ADULT RESPIRATORY DISTRESS SYNDROME; ANTIVIRAL THERAPY; APLASTIC ANEMIA; BRAIN INFECTION; CEREBELLITIS; COMBINATION CHEMOTHERAPY; DISEASE SEVERITY; FACIAL NERVE PARALYSIS; GUILLAIN BARRE SYNDROME; HEPATITIS; HUMAN; IMMUNE DEFICIENCY; INFECTIOUS MONONUCLEOSIS; MENINGOENCEPHALITIS; MONOTHERAPY; MYELORADICULITIS; MYOCARDITIS; PRIORITY JOURNAL; RADICULITIS; REVIEW; THROMBOCYTOPENIA; TREATMENT OUTCOME; ULCER; VASCULITIS;

ACYCLOVIR; ANTIVIRAL AGENTS; EPSTEIN-BARR VIRUS INFECTIONS; HUMANS;

EID: 77957684688     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2010.07.008     Document Type: Review

References (49)

1. Cohen J.I. Epstein-Barr virus infection. N Engl J Med 2000, 343:481-492.
2. Quintanilla-Martinez L., Kumar S., Fend F., Reyes E., Teruya-Feldstein J., Kingma D.W., et al. Fulminant EBV (+) T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome. Blood 2000, 96(2):443-451.
3. Linde A., Kallin B., Dillner J., Andersson J., Jägdahl L., Lindvall A., et al. Evaluation of enzyme-linked immunosorbent assays with two synthetic peptides of Epstein-Barr virus for diagnosis of infectious mononucleosis. Infect Dis 1990, 161(5):903-909.
4. Svahn A., Magnusson M., Jägdahl L., Schloss L., Kahlmeter G., Linde A. Evaluation of three commercial enzyme-linked immunosorbent assays and two latex agglutination assays for diagnosis of primary Epstein-Barr virus infection. J Clin Microbiol 1997, 35(11):2728-2732.
5. Zingg W., Bossart W., Berli E., Nadal D. Detection and quantification of cell-free Epstein-Barr virus by polymerase chain reaction and subsequent DNA enzyme immunoassay. J Virol Methods 1999, 79(2):141-148.
6. Ma C., Wong C.K., Wong B.C., Chan K.C., Lun S.W., Lee N., et al. Cytokine responses in a severe case of glandular fever treated successfully with foscarnet combined with prednisolone and intravenous immunoglobulin. J Med Virol 2009, 81:99-105.
7. Farrando J., Fonollosa A., Segura A., Garcia-Arumi J. Frosted branch angiitis associated with Epstein-Barr virus systemic infection. Ocul Immunol Inflamm 2008, 16:41-43.
8. Sanefuji M., Ohga S., Kira R., Nomura A., Torisu H., Takada H., et al. Epstein-Barr virus-associated meningoencephalomyelitis: intrathecal reactivation of the virus in an immunocompetent child. J Child Neurol 2008, 23:1072-1077.
9. Riachy M., Baaklini C., Ibrahim I., Azar H., Yaghi C., Dabar G., et al. Acute respiratory distress syndrome complicating Epstein-Barr virus pneumonia. Rev Mal Respir 2007, 24:639-643. French.
10. Bahadori H.R., Williams V.C., Turner R.P., Rumboldt Z., Reigart J.R., Fowler S.L., et al. Acute disseminated encephalomyelitis following infectious mononucleosis. J Child Neurol 2007, 22:324-328.
11. Adams L.A., Deboer B., Jeffrey G., Marley R., Garas G. Ganciclovir and the treatment of Epstein-Barr virus hepatitis. J Gastroenterol Hepatol 2006, 21:1758-1760.
12. Højberg L., Søndergård E., Pedersen C. A case of Epstein-Barr virus infection complicated with Guillain-Barré syndrome involving several cranial nerves. Scand J Infect Dis 2005, 37:522-524.
13. Lorenzo C.V., Robertson W.S. Genital ulcerations as presenting symptom of infectious mononucleosis. J Am Board Fam Pract 2005, 18:67-68.
14. Francisci D., Sensini A., Fratini D., Moretti M.V., Luchetta M.L., Di Caro A., et al. Acute fatal necrotizing hemorrhagic encephalitis caused by Epstein-Barr virus in a young adult immunocompetent man. J Neurovirol 2004, 10(6):414-417.
15. Terada K., Niizuma T., Kosaka Y., Inoue M., Ogita S., Kataoka N. Bilateral facial nerve palsy associated with Epstein-Barr virus infection with a review of the literature. Scand J Infect Dis 2004, 36:75-77.
16. Fujimoto H., Asaoka K., Imaizumi T., Ayabe M., Shoji H., Kaji M. Epstein-Barr virus infections of the central nervous system. Intern Med 2003, 42(1):33-40.
17. Gautschi O., Berger C., Gubler J., Laube I. Acute respiratory failure and cerebral hemorrhage due to primary Epstein-Barr virus infection. Respiration 2003, 70:419-422.
18. Ortí A., Otero M.C., Tallón P., Merlos R., Pérez-Tamarit D., Morant A., et al. Epstein-Barr virus mononucleosis: neurologic complications. Clin Pediatr (Phila) 2003, 42:361-364.
19. Tsai J.D., Lee H.C., Lin C.C., Liang D.C., Chen S.H., Huang F.Y. Epstein-Barr virus-associated acute renal failure: diagnosis, treatment, and follow-up. Pediatr Nephrol 2003, 18:667-674.
20. Goldani L.Z. Treatment of severe infectious mononucleosis with famciclovir. J Infect 2002, 44:92-93.
21. Simon M.W. Treatment of Epstein-Barr virus illness: an illustrative case. Int Pediatr 2002, 17:21-23.
22. Mori T., Nagai K., Asanuma H. Reactivation of varicella-zoster virus in facial palsy associated with infectious mononucleosis. Pediatr Infect Dis J 2002, 21:709-711.
23. Majid A., Galetta S.L., Sweeney C.J., Robinson C., Mahalingam R., Smith J., et al. Epstein-Barr virus myeloradiculitis and encephalomyeloradiculitis. Brain 2002, 125(Pt 1):159-165.
24. Baykurt C., Kudret C., Ceviz N., Akyuz C., Secmeer G. Successful treatment of Epstein-Barr virus infection associated with myocarditis. Pediatr Int 2002, 41:389-391.
25. Kimura H., Nagasaka T., Hoshino Y., Hayashi N., Tanaka N., Xu J.L., et al. Severe hepatitis caused by Epstein-Barr virus without infection of hepatocytes. Hum Pathol 2001, 32:757-762.
26. Follet-Bouhamed C., Nassimi A., Troller S., Loiseau-Corvez M.N., Berthier M., Oriot D. A cause of acute encephalitis: primo-infection due to Epstein-Barr virus. Arch Pediatr 1999, 6:286-289. French.
27. Feranchak A.P., Tyson R.W., Narkewicz M.R., Karrer F.M., Sokol R.J. Fulminant Epstein-Barr viral hepatitis: orthotopic liver transplantation and review of the literature. Liver Transpl Surg 1998, 4:469-476.
28. Greene W.L., Craft J. A man with fever and petechiae. Lancet 1997, 349:696.
29. de Fraiture D.M., Sie T.H., Boezeman E.H., Haanen H.C. Cerebellitis as an uncommon complication of infectious mononucleosis. Neth J Med 1997, 51:79-82.
30. Merelli E., Bedin R., Sola P., Gentilini M., Pietrosemoli P., Meacci M., et al. Encephalomyeloradiculopathy associated with Epstein-Barr virus: primary infection or reactivation?. Acta Neurol Scand 1997, 96:416-420.
31. Tselis A., Duman R., Storch G.A., Lisak R.P. Epstein-Barr virus encephalomyelitis diagnosed by polymerase chain reaction: detection of the genome in the CSF. Neurology 1997, 48:1351-1355.
32. Morgenlander J.C. A syndrome of concurrent central and peripheral nervous system involvement due to Epstein-Barr virus infection. Muscle Nerve 1996, 19:1037-1039.
33. Mayer H.B., Wanke C.A., Williams M., Crosson A.W., Federman M., Hammer S.M. Epstein-Barr virus-induced infectious mononucleosis complicated by acute renal failure: case report and review. Clin Infect Dis 1996, 22:1009-1018.
34. Shian W.J., Chi C.S. Fatal brainstem encephalitis caused by Epstein-Barr virus. Pediatr Radiol 1994, 24:596-597.
35. Tsutsumi H., Kamazaki H., Nakata S., Nagao, Chiba S., Imai S., et al. Sequential development of acute meningoencephalitis and transverse myelitis caused by Epstein-Barr virus during infectious mononucleosis. Pediatr Infect Dis J 1994, 13:665-667.
36. Lau Y.L., Srivastava G., Lee C.W., Kwong K.Y., Yeung C.Y. Epstein-Barr virus associated aplastic anaemia and hepatitis. J Paediatr Child Health 1994, 30:74-76.
37. Baumgarten E., Herbst H., Schmitt M., Seeger K.H., Schulte-Overberg U., Henze G. Life-threatening infectious mononucleosis: is it correlated with virus-induced T cell proliferation?. Clin Infect Dis 1994, 19:152-156.
38. McKendall R.R., Sadiq S.A., Calverley J.R. Unusual manifestations of Epstein-Barr virus encephalomyelitis. Infection 1990, 18:33-35.
39. Bhatti N., Larson E., Hickey M., Seal D. Encephalitis due to Epstein-Barr virus. J Infect 1990, 20:69-72.
40. Bétrémieux P., André P., Casadevall I., Abdelnabi K., La Rocca M.C., Lefrançois C. Fatal acute encephalitis in primary Epstein-Barr virus infection. Arch Fr Pediatr 1990, 47:513-514. French.
41. Hugo H., Linde A., Abom P.E. Epstein-Barr virus induced thrombocytopenia treated with intravenous acyclovir and immunoglobulin. Scand J Infect Dis 1989, 21:103-105.
42. Demey H.E., Martin J.J., Leus R.M., Moeremans C.J., Bossaert L.L. Coma as a presenting sign of Epstein-Barr encephalitis. Arch Intern Med 1988, 148:1459-1461.
43. Hart G.K., Thompson W.R., Schneider J., Davis N.J., Oh T.E. Fulminant hepatic failure and fatal encephalopathy associated with Epstein-Barr virus infection. Med J Aust 1984, 141:112-113.
44. Berkovic S.F., Bladin P.F., Walsh K.W. Infectious mononucleosis encephalitis. Possible therapeutic response to vidarabine. Med J Aust 1982, 2:343-344.
45. Torre D., Tambini R. Acyclovir for treatment of infectious mononucleosis: a meta-analysis. Scand J Infect Dis 1999, 31:543-547.
46. Pagano J.S., Sixbey J.W., Lin J.C. Acyclovir and Epstein-Barr virus infection. J Antimicrob Chemother 1983, 12(Suppl. B):113-121.
47. Andersson J., Britton S., Ernberg I., Andersson U., Henle W., Sköldenberg B., et al. Effect of acyclovir on infectious mononucleosis: a double-blind, placebo-controlled study. J Infect Dis 1986, 153(2):283-290.
48. Rafailidis P.I., Mourtzoukou E.G., Varbobitis I.C., Falagas M.E. Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review. Virol J 2008, 5:47.
49. Gershburg E., Pagano J.S. Epstein-Barr virus infections: prospects for treatment. J Antimicrob Chemother 2005, 56:277-281.