A biosensor study indicating that entropy, electrostatics, and receptor glycosylation drive the binding interaction between interleukin-7 and its receptor

Biochemistry

Volumn 49, Issue 40, 2010, Pages 8766-8778

  Walsh, Scott T R ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC MECHANISMS; BINDING AFFINITIES; BINDING INTERACTION; BINDING INTERFACE; BIOPHYSICAL STUDIES; CHARGE INTERACTIONS; ELECTROSTATIC COMPONENTS; ENTHALPY CHANGE; ENTROPY CHANGES; EXTRACELLULAR DOMAINS; GLYCOSYLATED; HEAT CAPACITY CHANGE; INTERLEUKIN-7; N-GLYCAN; N-GLYCANS; N-LINKED GLYCOSYLATION; REACTION PATHWAYS; SALT CONCENTRATION; SURFACE PLASMON RESONANCE SPECTROSCOPY; T CELLS; TRANSITION-STATE; TRANSITION-STATE BINDING; TWO-STEP REACTIONS; VAN'T HOFF ANALYSIS;

BINDING ENERGY; BIOSENSORS; ELECTROSTATICS; ENTHALPY; ENTROPY; ESTERIFICATION; GLYCOSYLATION; REDUCTION; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

REACTION RATES;

INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; SODIUM CHLORIDE;

ARTICLE; BINDING AFFINITY; BIOSENSOR; CIRCULAR DICHROISM; ENTHALPY; ENTROPY; GLYCOSYLATION; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; STATIC ELECTRICITY; SURFACE PLASMON RESONANCE; TEMPERATURE; THERMODYNAMICS;

BIOSENSING TECHNIQUES; ENTROPY; GLYCOSYLATION; HUMANS; INTERLEUKIN-7; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN-7; SODIUM CHLORIDE; STATIC ELECTRICITY;

EID: 77957683633     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101050h     Document Type: Article

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