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Volumn 6, Issue 11, 2010, Pages 2316-2324

Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis

(13) Ekins, Sean a,b,c,d Kaneko, Takushi e Lipinski, Christopher A f Bradford, Justin a Dole, Krishna a Spektor, Anna a Gregory, Kellan a Blondeau, David a Ernst, Sylvia a Yang, Jeremy g Goncharoff, Nicko h Hohman, Moses M a Bunin, Barry A a

a Collaborative Drug Discovery ^* (United States)

b Collaborations in Chemistry ^* (United States)

c UNIVERSITY OF MARYLAND (United States)

d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL (United States)

e GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (United States)

f University of New Mexico ^* (United States)

g UNIVERSITY OF NEW MEXICO (United States)

h SureChem Macmillan Building (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TUBERCULOSTATIC AGENT;

ARTICLE; BAYES THEOREM; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; FACTUAL DATABASE; MOLECULAR LIBRARY; MYCOBACTERIUM TUBERCULOSIS;

ANTITUBERCULAR AGENTS; BAYES THEOREM; DATABASES, FACTUAL; DRUG EVALUATION, PRECLINICAL; MYCOBACTERIUM TUBERCULOSIS; SMALL MOLECULE LIBRARIES;

MYCOBACTERIUM TUBERCULOSIS;

EID: 77957680455 PISSN: 1742206X EISSN: 17422051 Source Type: Journal
DOI: 10.1039/c0mb00104j Document Type: Article

Times cited : (69)

References (41)

1
- 54349105873
- T. S. Balganesh P. M. Alzari S. T. Cole Trends Pharmacol. Sci. 2008 29 576 581
- (2008) Trends Pharmacol. Sci. , vol.29 , pp. 576-581
- Balganesh, T.S.¹ Alzari, P.M.² Cole, S.T.³

2
- 19544390716
- L. Ballel R. A. Field K. Duncan R. J. Young Antimicrob. Agents Chemother. 2005 49 2153 2163
- (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 2153-2163
- Ballel, L.¹ Field, R.A.² Duncan, K.³ Young, R.J.⁴

3
- 77952326917
- S. Ekins J. Bradford K. Dole A. Spektor K. Gregory D. Blondeau M. Hohman B. Bunin Mol. BioSyst. 2010 6 840 851
- (2010) Mol. BioSyst. , vol.6 , pp. 840-851
- Ekins, S.¹ Bradford, J.² Dole, K.³ Spektor, A.⁴ Gregory, K.⁵ Blondeau, D.⁶ Hohman, M.⁷ Bunin, B.⁸

4
- 70449108128
- J. A. Maddry S. Ananthan R. C. Goldman J. V. Hobrath C. D. Kwong C. Maddox L. Rasmussen R. C. Reynolds J. A. Secrist, 3rd M. I. Sosa E. L. White W. Zhang Tuberculosis 2009 89 354 363
- (2009) Tuberculosis , vol.89 , pp. 354-363
- Maddry, J.A.¹ Ananthan, S.² Goldman, R.C.³ Hobrath, J.V.⁴ Kwong, C.D.⁵ Maddox, C.⁶ Rasmussen, L.⁷ Reynolds, R.C.⁸ Secrist III, J.A.⁹ Sosa, M.I.¹⁰ White, E.L.¹¹ Zhang, W.¹²

5
- 70350765485
- S. Ananthan E. R. Faaleolea R. C. Goldman J. V. Hobrath C. D. Kwong B. E. Laughon J. A. Maddry A. Mehta L. Rasmussen R. C. Reynolds J. A. Secrist, 3rd N. Shindo D. N. Showe M. I. Sosa W. J. Suling E. L. White Tuberculosis 2009 89 334 353
- (2009) Tuberculosis , vol.89 , pp. 334-353
- Ananthan, S.¹ Faaleolea, E.R.² Goldman, R.C.³ Hobrath, J.V.⁴ Kwong, C.D.⁵ Laughon, B.E.⁶ Maddry, J.A.⁷ Mehta, A.⁸ Rasmussen, L.⁹ Reynolds, R.C.¹⁰ Secrist III, J.A.¹¹ Shindo, N.¹² Showe, D.N.¹³ Sosa, M.I.¹⁴ Suling, W.J.¹⁵ White, E.L.¹⁶

6
- 43949129098
- R. O'Shea H. E. Moser J. Med. Chem. 2008 51 2871 2878
- (2008) J. Med. Chem. , vol.51 , pp. 2871-2878
- O'Shea, R.¹ Moser, H.E.²

7
- 33845903833
- D. A. Payne M. N. Gwynn D. J. Holmes D. L. Pompliano Nat. Rev. Drug Discovery 2007 6 29 40
- (2007) Nat. Rev. Drug Discovery , vol.6 , pp. 29-40
- Payne, D.A.¹ Gwynn, M.N.² Holmes, D.J.³ Pompliano, D.L.⁴

8
- 0033986977
- C. E. Barry, 3rd R. A. Slayden A. E. Sampson R. E. Lee Biochem. Pharmacol. 2000 59 221 231
- (2000) Biochem. Pharmacol. , vol.59 , pp. 221-231
- Barry III, C.E.¹ Slayden, R.A.² Sampson, A.E.³ Lee, R.E.⁴

9
- 76749147365
- A. J. Williams V. Tkachenko C. Lipinski A. Tropsha S. Ekins Drug Discovery World 2009
- (2009) Drug Discovery World
- Williams, A.J.¹ Tkachenko, V.² Lipinski, C.³ Tropsha, A.⁴ Ekins, S.⁵

10
- 0037204546
- W. P. Walters M. A. Murcko Adv. Drug Delivery Rev. 2002 54 255 271
- (2002) Adv. Drug Delivery Rev. , vol.54 , pp. 255-271
- Walters, W.P.¹ Murcko, M.A.²

11
- 0033194752
- M. Hann B. Hudson X. Lewell R. Lifely L. Miller N. Ramsden J. Chem. Inf. Comput. Sci. 1999 39 897 902
- (1999) J. Chem. Inf. Comput. Sci. , vol.39 , pp. 897-902
- Hann, M.¹ Hudson, B.² Lewell, X.³ Lifely, R.⁴ Miller, L.⁵ Ramsden, N.⁶

12
- 33745381593
- B. C. Pearce M. J. Sofia A. C. Good D. M. Drexler D. A. Stock J. Chem. Inf. Model. 2006 46 1060 1068
- (2006) J. Chem. Inf. Model. , vol.46 , pp. 1060-1068
- Pearce, B.C.¹ Sofia, M.J.² Good, A.C.³ Drexler, D.M.⁴ Stock, D.A.⁵

13
- 11844253252
- J. R. Huth R. Mendoza E. T. Olejniczak R. W. Johnson D. A. Cothron Y. Liu C. G. Lerner J. Chen P. J. Hajduk J. Am. Chem. Soc. 2005 127 217 224
- (2005) J. Am. Chem. Soc. , vol.127 , pp. 217-224
- Huth, J.R.¹ Mendoza, R.² Olejniczak, E.T.³ Johnson, R.W.⁴ Cothron, D.A.⁵ Liu, Y.⁶ Lerner, C.G.⁷ Chen, J.⁸ Hajduk, P.J.⁹

14
- 38149108462
- J. R. Huth D. Song R. R. Mendoza C. L. Black-Schaefer J. C. Mack S. A. Dorwin U. S. Ladror J. M. Severin K. A. Walter D. M. Bartley P. J. Hajduk Chem. Res. Toxicol. 2007 20 1752 1759
- (2007) Chem. Res. Toxicol. , vol.20 , pp. 1752-1759
- Huth, J.R.¹ Song, D.² Mendoza, R.R.³ Black-Schaefer, C.L.⁴ MacK, J.C.⁵ Dorwin, S.A.⁶ Ladror, U.S.⁷ Severin, J.M.⁸ Walter, K.A.⁹ Bartley, D.M.¹⁰ Hajduk, P.J.¹¹

15
- 33947194049
- J. T. Metz J. R. Huth P. J. Hajduk J. Comput.-Aided Mol. Des. 2007 21 139 144
- (2007) J. Comput.-Aided Mol. Des. , vol.21 , pp. 139-144
- Metz, J.T.¹ Huth, J.R.² Hajduk, P.J.³

16
- 77950571108
- J. B. Baell G. A. Holloway J. Med. Chem. 2010 53 2719 2740
- (2010) J. Med. Chem. , vol.53 , pp. 2719-2740
- Baell, J.B.¹ Holloway, G.A.²

17
- 65649096556
- V. Makarov G. Manina K. Mikusova U. Mollmann O. Ryabova B. Saint-Joanis N. Dhar M. R. Pasca S. Buroni A. P. Lucarelli A. Milano E. De Rossi M. Belanova A. Bobovska P. Dianiskova J. Kordulakova C. Sala E. Fullam P. Schneider J. D. McKinney P. Brodin T. Christophe S. Waddell P. Butcher J. Albrethsen I. Rosenkrands R. Brosch V. Nandi S. Bharath S. Gaonkar R. K. Shandil V. Balasubramanian T. Balganesh S. Tyagi J. Grosset G. Riccardi S. T. Cole Science 2009 324 801 804
- (2009) Science , vol.324 , pp. 801-804
- Makarov, V.¹ Manina, G.² Mikusova, K.³ Mollmann, U.⁴ Ryabova, O.⁵ Saint-Joanis, B.⁶ Dhar, N.⁷ Pasca, M.R.⁸ Buroni, S.⁹ Lucarelli, A.P.¹⁰ Milano, A.¹¹ De Rossi, E.¹² Belanova, M.¹³ Bobovska, A.¹⁴ Dianiskova, P.¹⁵ Kordulakova, J.¹⁶ Sala, C.¹⁷ Fullam, E.¹⁸ Schneider, P.¹⁹ McKinney, J.D.²⁰ more..

18
- 67349287483
- N. Willand B. Dirie X. Carette P. Bifani A. Singhal M. Desroses F. Leroux E. Willery V. Mathys R. Deprez-Poulain G. Delcroix F. Frenois M. Aumercier C. Locht V. Villeret B. Deprez A. R. Baulard Nat. Med. 2009 15 537 544
- (2009) Nat. Med. , vol.15 , pp. 537-544
- Willand, N.¹ Dirie, B.² Carette, X.³ Bifani, P.⁴ Singhal, A.⁵ Desroses, M.⁶ Leroux, F.⁷ Willery, E.⁸ Mathys, V.⁹ Deprez-Poulain, R.¹⁰ Delcroix, G.¹¹ Frenois, F.¹² Aumercier, M.¹³ Locht, C.¹⁴ Villeret, V.¹⁵ Deprez, B.¹⁶ Baulard, A.R.¹⁷

19
- 61849137243
- M. Hohman K. Gregory K. Chibale P. J. Smith S. Ekins B. Bunin Drug Discovery Today 2009 14 261 270
- (2009) Drug Discovery Today , vol.14 , pp. 261-270
- Hohman, M.¹ Gregory, K.² Chibale, K.³ Smith, P.J.⁴ Ekins, S.⁵ Bunin, B.⁶

20
- 77952704258
- F.-J. Gamo L. M. Sanz J. Vidal C. de Cozar E. Alvarez J.-L. Lavandera D. E. Vanderwall D. V. S. Green V. Kumar S. Hasan J. R. Brown C. E. Peishoff L. R. Cardon J. F. Garcia-Bustos Nature 2010 465 305 310
- (2010) Nature , vol.465 , pp. 305-310
- Gamo, F.-J.¹ Sanz, L.M.² Vidal, J.³ De Cozar, C.⁴ Alvarez, E.⁵ Lavandera, J.-L.⁶ Vanderwall, D.E.⁷ Green, D.V.S.⁸ Kumar, V.⁹ Hasan, S.¹⁰ Brown, J.R.¹¹ Peishoff, C.E.¹² Cardon, L.R.¹³ Garcia-Bustos, J.F.¹⁴

21
- 34548070044
- D. R. Jones S. Ekins L. Li S. D. Hall Drug Metab. Dispos. 2007 35 1466 1475
- (2007) Drug Metab. Dispos. , vol.35 , pp. 1466-1475
- Jones, D.R.¹ Ekins, S.² Li, L.³ Hall, S.D.⁴

22
- 0000381930
- A. K. Ghose V. N. Viswanadhan J. J. Wendoloski J. Phys. Chem. 1998 102 3762 3772
- (1998) J. Phys. Chem. , vol.102 , pp. 3762-3772
- Ghose, A.K.¹ Viswanadhan, V.N.² Wendoloski, J.J.³

23
- 0029894013
- G. W. Bemis M. A. Murcko J. Med. Chem. 1996 39 2887 2893
- (1996) J. Med. Chem. , vol.39 , pp. 2887-2893
- Bemis, G.W.¹ Murcko, M.A.²

24
- 0035996571
- T. J. Monks D. C. Jones Curr. Drug Metab. 2002 3 425 438
- (2002) Curr. Drug Metab. , vol.3 , pp. 425-438
- Monks, T.J.¹ Jones, D.C.²

25
- 37349033017
- J. C. Sacchettini E. J. Rubin J. S. Freundlich Nat. Rev. Microbiol. 2008 6 41 52
- (2008) Nat. Rev. Microbiol. , vol.6 , pp. 41-52
- Sacchettini, J.C.¹ Rubin, E.J.² Freundlich, J.S.³

26
- 77957914933
- S. Ekins and A. J. Williams, 2010, submitted
- S. Ekins and A. J. Williams, 2010, submitted

27
- 77953138779
- A. Talukdar E. Morgunova J. Duan W. Meining N. Foloppe L. Nilsson A. Bacher B. Illarionov M. Fischer R. Ladenstein M. Cushman Bioorg. Med. Chem. 2010 18 3518 3534
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 3518-3534
- Talukdar, A.¹ Morgunova, E.² Duan, J.³ Meining, W.⁴ Foloppe, N.⁵ Nilsson, L.⁶ Bacher, A.⁷ Illarionov, B.⁸ Fischer, M.⁹ Ladenstein, R.¹⁰ Cushman, M.¹¹

28
- 77957908498
- submitted
- S. Ekins, J. S. Freundlich, I. Choi, M. Sarker and C. Talcott, 2010, submitted
- (2010)
- Ekins, S.¹ Freundlich, J.S.² Choi, I.³ Sarker, M.⁴ Talcott, C.⁵

29
- 58149105628
- P. Prathipati N. L. Ma T. H. Keller J. Chem. Inf. Model. 2008 48 2362 2370
- (2008) J. Chem. Inf. Model. , vol.48 , pp. 2362-2370
- Prathipati, P.¹ Ma, N.L.² Keller, T.H.³

30
- 0035899174
- O. Llorens J. J. Perez H. O. Villar J. Med. Chem. 2001 44 2793 2804
- (2001) J. Med. Chem. , vol.44 , pp. 2793-2804
- Llorens, O.¹ Perez, J.J.² Villar, H.O.³

31
- 53549091061
- Y. Cho T. R. Ioerger J. C. Sacchettini J. Med. Chem. 2008 51 5984 5992
- (2008) J. Med. Chem. , vol.51 , pp. 5984-5992
- Cho, Y.¹ Ioerger, T.R.² Sacchettini, J.C.³

32
- 57149099588
- R. Singh U. Manjunatha H. I. Boshoff Y. H. Ha P. Niyomrattanakit R. Ledwidge C. S. Dowd I. Y. Lee P. Kim L. Zhang S. Kang T. H. Keller J. Jiricek C. E. Barry, 3rd Science 2008 322 1392 1395
- (2008) Science , vol.322 , pp. 1392-1395
- Singh, R.¹ Manjunatha, U.² Boshoff, H.I.³ Ha, Y.H.⁴ Niyomrattanakit, P.⁵ Ledwidge, R.⁶ Dowd, C.S.⁷ Lee, I.Y.⁸ Kim, P.⁹ Zhang, L.¹⁰ Kang, S.¹¹ Keller, T.H.¹² Jiricek, J.¹³ Barry III, C.E.¹⁴

33
- 64349096833
- P. Kim S. Kang H. I. Boshoff J. Jiricek M. Collins R. Singh U. H. Manjunatha P. Niyomrattanakit L. Zhang M. Goodwin T. Dick T. H. Keller C. S. Dowd C. E. Barry J. Med. Chem. 2009 52 1329 1344
- (2009) J. Med. Chem. , vol.52 , pp. 1329-1344
- Kim, P.¹ Kang, S.² Boshoff, H.I.³ Jiricek, J.⁴ Collins, M.⁵ Singh, R.⁶ Manjunatha, U.H.⁷ Niyomrattanakit, P.⁸ Zhang, L.⁹ Goodwin, M.¹⁰ Dick, T.¹¹ Keller, T.H.¹² Dowd, C.S.¹³ Barry, C.E.¹⁴

34
- 60549111040
- P. Axerio-Cilies I. P. Castaneda A. Mirza J. Reynisson Eur. J. Med. Chem. 2009 44 1128 1134
- (2009) Eur. J. Med. Chem. , vol.44 , pp. 1128-1134
- Axerio-Cilies, P.¹ Castaneda, I.P.² Mirza, A.³ Reynisson, J.⁴

35
- 0034460173
- S. Ekins C. L. Waller P. W. Swaan G. Cruciani S. A. Wrighton J. H. Wikel J. Pharmacol. Toxicol. Methods 2000 44 251 272
- (2000) J. Pharmacol. Toxicol. Methods , vol.44 , pp. 251-272
- Ekins, S.¹ Waller, C.L.² Swaan, P.W.³ Cruciani, G.⁴ Wrighton, S.A.⁵ Wikel, J.H.⁶

36
- 0036589360
- S. Ekins B. Boulanger P. W. Swaan M. A. Z. Hupcey J. Comput.-Aided Mol. Des. 2002 16 381 401
- (2002) J. Comput.-Aided Mol. Des. , vol.16 , pp. 381-401
- Ekins, S.¹ Boulanger, B.² Swaan, P.W.³ Hupcey, M.A.Z.⁴

37
- 77957924192
- R. R. Gupta E. M. Gifford T. Liston C. L. Waller B. Bunin S. Ekins Drug Metab. Dispos. 2010
- (2010) Drug Metab. Dispos.
- Gupta, R.R.¹ Gifford, E.M.² Liston, T.³ Waller, C.L.⁴ Bunin, B.⁵ Ekins, S.⁶

38
- 77950531688
- S. Ekins A. J. Williams Lab Chip 2010 10 13 22
- (2010) Lab Chip , vol.10 , pp. 13-22
- Ekins, S.¹ Williams, A.J.²

39
- 84889611652
- John Wiley and Sons, Hoboken, NJ
- S. Ekins, Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals, John Wiley and Sons, Hoboken, NJ, 2007
- (2007) Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals
- Ekins, S.¹

40
- 15944425080
- S. Ekins Y. Nikolsky T. Nikolskaya Trends Pharmacol. Sci. 2005 26 202 209
- (2005) Trends Pharmacol. Sci. , vol.26 , pp. 202-209
- Ekins, S.¹ Nikolsky, Y.² Nikolskaya, T.³

41
- 57349154252
- A. Gupte H. I. Boshoff D. J. Wilson J. Neres N. P. Labello R. V. Somu C. Xing C. E. Barry C. C. Aldrich J. Med. Chem. 2008 51 7495 7507
- (2008) J. Med. Chem. , vol.51 , pp. 7495-7507
- Gupte, A.¹ Boshoff, H.I.² Wilson, D.J.³ Neres, J.⁴ Labello, N.P.⁵ Somu, R.V.⁶ Xing, C.⁷ Barry, C.E.⁸ Aldrich, C.C.⁹

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