Trimethoprim/sulfamethoxazole pharmacokinetics in two patients undergoing continuous venovenous hemodiafiltration

Annals of Pharmacotherapy

Volumn 44, Issue 10, 2010, Pages 1669-1672

  Curkovic, Ivanka ^a   Lüthi, Beatrice ^a   Franzen, Daniel ^a   Ceschi, Alessandro ^a   Rudiger, Alain ^a   Corti, Natascia ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Continuous venovenous hemodiafiltration; Pharmacokinetics; Sulfamethoxazole; Trimethoprim

Indexed keywords

CYCLOSPORIN; METHOTREXATE; POLYSULFONE; PREDNISONE; SULFAMETHOXAZOLE; TRIMETHOPRIM;

ACUTE KIDNEY FAILURE; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; AORTIC ROOT SURGERY; ARTICLE; ARTIFICIAL VENTILATION; ASPIRATION PNEUMONIA; BLOOD FLOW VELOCITY; BODY SURFACE; CASE REPORT; CONTINUOUS HEMODIAFILTRATION; CRITICALLY ILL PATIENT; DIALYSATE; DIVERTICULITIS; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG MEGADOSE; ENTEROBACTER CLOACAE; FEMALE; GLOMERULUS FILTRATION RATE; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; KIDNEY CLEARANCE; KIDNEY FUNCTION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PNEUMOCYSTIS JIROVECI; PNEUMOCYSTIS PNEUMONIA; POLYMYOSITIS; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; RESPIRATORY FAILURE; SEPTIC SHOCK; STEADY STATE; STENOTROPHOMONAS MALTOPHILIA; THORAX RADIOGRAPHY; TREATMENT RESPONSE; XENOGRAFT;

ACUTE KIDNEY INJURY; AGED; ANTI-INFECTIVE AGENTS; CRITICAL ILLNESS; CROSS INFECTION; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HEMODIAFILTRATION; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; PNEUMONIA, PNEUMOCYSTIS; STENOTROPHOMONAS MALTOPHILIA; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 77957674693     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1P160     Document Type: Article

References (14)

1. Mofenson LM, Oleske J, Serchuck L, Van Dyke R, Wilfert C. Treating opportunistic infections among HIV-exposed and infected children: recommendations from CDC, the National Institutes of Health, and the Infectious Diseases Society of America. MMWR Recomm Rep 2004;53:1-92. DOI 10.1086/427295
2. Looney WJ, Narita M, Muhlemann K. Stenotrophomonas maltophilia: an emerging opportunist human pathogen. Lancet Infect Dis 2009;9:312-23. DOI 10.1016/S1473-3099(09)70083-0
3. Patel RB, Welling PG. Clinical pharmacokinetics of co-trimoxazole (trimethoprim-sulphamethoxazole). Clin Pharmacokinet 1980;5:405-23. DOI 10.2165/00003088-198005050-00001
4. Siber GR, Gorham CC, Ericson JF, Smith AL. Pharmacokinetics of intravenous trimethoprim-sulfamethoxazole in children and adults with normal and impaired renal function. Rev Infect Dis 1982;4:566-78.
5. Joos B, Schmidli M, Keusch G. Pharmacokinetics of antimicrobial agents in anuric patients during continuous venovenous haemofiltration. Nephrol Dial Transplant 1996;11:1582-5.
6. Nissenson AR, Wilson C, Holazo A. Pharmacokinetics of intravenous trimethoprim-sulfamethoxazole during hemodialysis. Am J Nephrol 1987;7:270-4. DOI 10.1159/000167484
7. Bugge JF. Pharmacokinetics and drug dosing adjustments during continuous venovenous hemofiltration or hemodiafiltration in critically ill patients. Acta Anaesthesiol Scand 2001;45:929-34. DOI 10.1034/j.1399-6576.2001.450802.x
8. Bouman CS, van Kan HJ, Koopmans RP, Korevaar JC, Schultz MJ, Vroom MB. Discrepancies between observed and predicted continuous venovenous hemofiltration removal of antimicrobial agents in critically ill patients and the effects on dosing. Intensive Care Med 2006;32:2013-9. DOI 10.1007/s00134-006-0397-x
9. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-70.
10. Product information. Bactrim (trimethoprim/sulfamethoxazole) injection. Reinach, Switzerland: Roche Pharma AG, November 2007.
11. Klinker H, Langmann P, Zilly M, Richter E. Drug monitoring during the treatment of AIDS-associated Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole. J Clin Pharm Ther 1998;23:149-54. DOI 10.1046/j.1365-2710.1998.00152.x
12. Sattler FR, Cowan R, Nielsen DM, Ruskin J. Trimethoprim-sulfamethoxazole compared with pentamidine for treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A prospective, noncrossover study. Ann Intern Med 1988;109:280-7.
13. Wharton JM, Coleman DL, Wofsy CB, et al. Trimethoprim-sulfamethoxazole or pentamidine for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A prospective randomized trial. Ann Intern Med 1986;105:37-44.
14. Brunet S, Leblanc M, Geadah D, Parent D, Courteau S, Cardinal J. Diffusive and convective solute clearances during continuous renal replacement therapy at various dialysate and ultrafiltration flow rates. Am J Kidney Dis 1999;34:486-92. DOI 10.1016/S0272-6386(99)70076-4