Development of a clinically relevant liquid chromatography tandem mass spectrometry assay for 13 drugs of abuse in urine, designed to meet the needs of the service users

Annals of Clinical Biochemistry

Volumn 47, Issue 5, 2010, Pages 415-422

  Duxbury, K ^a   Romagnoli, C ^a   Anderson, M ^a   Watts, R ^b   Waite, G ^a  

^a SALFORD ROYAL NHS FOUNDATION TRUST   (United Kingdom)

^b WATERS CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCODEINE; AMPHETAMINE; BENZOYLECGONINE; BUPRENORPHINE; CODEINE; COTININE; DIHYDROCODEINE; DRUG METABOLITE; ILLICIT DRUG; METHADONE; MORPHINE; MORPHINE 6 ACETATE; NORCODEINE;

ACCURACY; ARTICLE; HYDROLYSIS; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINALYSIS; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LIMIT OF DETECTION; LINEAR MODELS; STREET DRUGS; SUBSTANCE ABUSE DETECTION; SUBSTANCE ABUSE TREATMENT CENTERS; TANDEM MASS SPECTROMETRY; URINALYSIS;

EID: 77957672877     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/acb.2010.010049     Document Type: Article

References (18)

1. www.dh.gov.uk/en/Publichealth/Healthimprovement/Drugmisuse/DH-085886 (last checked December 2009)
2. Levine MR, Rennie WP. Pre-employment urine drug testing of hospital employees: future questions and review of current literature. Occup Environ Med 2004;61:318-24
3. Braithwaite RA, Jarvie DR, Minty PSB, Simpson D, Widdop B. Screening for drugs of abuse I: opiates, amphetamines and cocaine. Ann Clin Biochem 1995;32:123-53
4. Simpson D, Braithwaite RA, Jarvie DR, et al. Screening for drugs of abuse (II): cannabinoids, lysergic acid diethylamide, buprenorphine, methadone, barbiturates, benzodiazepines and other drugs. Ann Clin Biochem 1997;34:460-510 (Pubitemid 27379832)
5. Verstraete AG, Heyden FV. Comparison of the sensitivity and specificity of 6 immunoassays for the detection of amphetamines in urine. J Anal Toxicol 2005;29:359-64
6. Eichhorst JC, Etter ML, Rousseaux N, Lehotay DC. Drugs of abuse testing by tandem mass spectrometry: A rapid simple method to replace immunoassays. Clin Biochem 2009;42:1531-42
7. Sudakin D, Power LE. Regional and temporal variation in methamphetamine related incidents: applications of spatial and temporal scan statistics. Clin Toxicol (Phila) 2009;47:243-7
8. Wells JE, Degenharat L, Bohnert KM, Anthony JC, Scott KM. Geographical clustering of cannabis use: results from the New Zealand Mental Health Survey 2003-2004. Drug Alcohol Depend 2009;99:309-16
9. de Wet CJ, Reed LJ, Bearn J. The rise of buprenorphine prescribing in England: analysis of NHS regional data, 2001-03. Addiction 2005;100:495-9 (Pubitemid 40529842)
10. Staub C, Marset M, Mino A, Mangin P. Detection of acetylcodeine in urine as an indicator of illicit heroin use: method validation and results of a pilot study. Clin Chem 2001;47:301-7
11. www.heathcontrol.com (last checked December 2009)
12. Chadwick CA, Keevil B. Measurement of cotinine in urine by liquid chromatography tandem mass spectrometry. Ann Clin Biochem 2007;44:455-62 (Pubitemid 351724654)
13. European Union Decision 2002/657/EC 17.08.2002. Commission decision laying down performance criteria for the analytical methods to be used for certain substances and residues thereof in live animals and animal products. Off J Eur Commun 2002;221:8-32
14. Brenneisen R, Hasler F, Wursch D. Acetylcodeine as a urinary marker to differentiate the use of street heroin and pharmaceutical heroin. J Anal Toxicol 2002;26:561-6 (Pubitemid 35453746)
15. Coles R, Kushnir MM, Nelson GJ, McMillin GA, Urry FM. Simultaneous determination of codeine, morphine, hydrocodone, hydromorphone, oxycodone and 6-acetylmorphine in urine, serum, plasma, whole blood and meconium by LC-MS/MS. J Anal Toxicol 2007;31:1-14
16. Cheng WC, Yau TS, Wong MK, Chan LP, Mok VKK. A high-throughput urinanalysis of abused drugs based on a SPE-LC-MS/MS method coupled with an in-house developed post analysis data treatment system. Forensic Sci Int 2006;162:95-107
17. Feng J, Wang L, Dai I, Harmon T, Bernet JT. Simultaneous determination of multiple drugs of abuse and relevant metabolites in urine by LC-MS-MS. J Anal Toxicol 2007;31:359-68 (Pubitemid 47451063)
18. Chen CY, Shen CC, Yang TJ, Chang YZ, Lee MR. High throughput screening of various abused drugs and metabolites in urine by liquid chromatography-heated electrospray ionization/tandem mass spectrometry. Talanta 2009;77:1351-7