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Volumn 1, Issue 5, 2010, Pages

GANP enhances the efficiency of mRNA nuclear export in mammalian cells

Author keywords

GANP; mRNA export; Nucleoporins

Indexed keywords

GERMINAL CENTER ASSOCIATED NUCLEAR PROTEIN; MESSENGER RIBONUCLEOPROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; NUCLEOPORIN; RIBONUCLEOPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NXF1; UNCLASSIFIED DRUG; ACYLTRANSFERASE;

EID: 77957671734     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.1.5.12351     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 0034460814 scopus 로고    scopus 로고
    • TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture
    • Herold A, Suyama M, Rodrigues JP, Braun IC, Kutay U, Carmo-Fonseca M, et al. TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. Mol Cell Biol 2000; 20:8996-9008.
    • (2000) Mol Cell Biol , vol.20 , pp. 8996-9008
    • Herold, A.1    Suyama, M.2    Rodrigues, J.P.3    Braun, I.C.4    Kutay, U.5    Carmo-Fonseca, M.6
  • 2
    • 0036315590 scopus 로고    scopus 로고
    • Nuclear export of mRNA by TAP/NXF1 requires two nucleoporin- binding sites but not p15
    • Braun IC, Herold A, Rode M, Izaurralde E. Nuclear export of mRNA by TAP/NXF1 requires two nucleoporin- binding sites but not p15. Mol Cell Biol 2002; 22:5405-18.
    • (2002) Mol Cell Biol , vol.22 , pp. 5405-5418
    • Braun, I.C.1    Herold, A.2    Rode, M.3    Izaurralde, E.4
  • 3
    • 0036215896 scopus 로고    scopus 로고
    • Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1
    • Grant RP, Hurt E, Neuhaus D, Stewart M. Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1. Nat Struct Biol 2002; 9:247-51.
    • (2002) Nat Struct Biol , vol.9 , pp. 247-251
    • Grant, R.P.1    Hurt, E.2    Neuhaus, D.3    Stewart, M.4
  • 4
    • 0037459067 scopus 로고    scopus 로고
    • Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1 A resolution
    • Grant RP, Neuhaus D, Stewart M. Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1 A resolution. J Mol Biol 2003; 326:849-58.
    • (2003) J Mol Biol , vol.326 , pp. 849-858
    • Grant, R.P.1    Neuhaus, D.2    Stewart, M.3
  • 5
    • 34648816826 scopus 로고    scopus 로고
    • Exporting RNA from the nucleus to the cytoplasm
    • Kohler A, Hurt E. Exporting RNA from the nucleus to the cytoplasm. Nat Rev Mol Cell Biol 2007; 8:761-73.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 761-773
    • Kohler, A.1    Hurt, E.2
  • 6
    • 0345643313 scopus 로고    scopus 로고
    • The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human
    • Katahira J, Strasser K, Podtelejnikov A, Mann M, Jung JU, Hurt E. The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J 1999; 18:2593-609.
    • (1999) EMBO J , vol.18 , pp. 2593-2609
    • Katahira, J.1    Strasser, K.2    Podtelejnikov, A.3    Mann, M.4    Jung, J.U.5    Hurt, E.6
  • 7
    • 0038697629 scopus 로고    scopus 로고
    • The interplay of nuclear mRNP assembly, mRNA surveillance and export
    • Stutz F, Izaurralde E. The interplay of nuclear mRNP assembly, mRNA surveillance and export. Trends Cell Biol 2003; 13:319-27.
    • (2003) Trends Cell Biol , vol.13 , pp. 319-327
    • Stutz, F.1    Izaurralde, E.2
  • 8
    • 33744967486 scopus 로고    scopus 로고
    • Dynamic nuclear pore complexes: Life on the edge
    • Tran EJ, Wente SR. Dynamic nuclear pore complexes: life on the edge. Cell 2006; 125:1041-53.
    • (2006) Cell , vol.125 , pp. 1041-1053
    • Tran, E.J.1    Wente, S.R.2
  • 9
    • 0033625090 scopus 로고    scopus 로고
    • REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/ Mex67p and participates in mRNA nuclear export
    • Stutz F, Bachi A, Doerks T, Braun IC, Seraphin B, Wilm M, et al. REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/ Mex67p and participates in mRNA nuclear export. RNA 2000; 6:638-50.
    • (2000) RNA , vol.6 , pp. 638-650
    • Stutz, F.1    Bachi, A.2    Doerks, T.3    Braun, I.C.4    Seraphin, B.5    Wilm, M.6
  • 10
    • 0034699472 scopus 로고    scopus 로고
    • The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
    • Zhou Z, Luo MJ, Straesser K, Katahira J, Hurt E, Reed R. The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 2000; 407:401-5.
    • (2000) Nature , vol.407 , pp. 401-405
    • Zhou, Z.1    Luo, M.J.2    Straesser, K.3    Katahira, J.4    Hurt, E.5    Reed, R.6
  • 11
    • 0344211508 scopus 로고    scopus 로고
    • SR splicing factors serve as adapter proteins for TAP-dependent mRNA export
    • Huang Y, Gattoni R, Stevenin J, Steitz JA. SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol Cell 2003; 11:837-43.
    • (2003) Mol Cell , vol.11 , pp. 837-843
    • Huang, Y.1    Gattoni, R.2    Stevenin, J.3    Steitz, J.A.4
  • 12
    • 0035846138 scopus 로고    scopus 로고
    • Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
    • Luo ML, Zhou Z, Magni K, Christoforides C, Rappsilber J, Mann M, et al. Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature 2001; 413:644-7.
    • (2001) Nature , vol.413 , pp. 644-647
    • Luo, M.L.1    Zhou, Z.2    Magni, K.3    Christoforides, C.4    Rappsilber, J.5    Mann, M.6
  • 13
    • 19344374094 scopus 로고    scopus 로고
    • SR proteins and export of mRNA
    • Reed R, Cheng H. TREX, SR proteins and export of mRNA. Curr Opin Cell Biol 2005; 17:269-73.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 269-273
    • Reed, R.1    Cheng, H.T.2
  • 14
    • 33845626622 scopus 로고    scopus 로고
    • Human mRNA export machinery recruited to the 5' end of mRNA
    • Cheng H, Dufu K, Lee CS, Hsu JL, Dias A, Reed R. Human mRNA export machinery recruited to the 5' end of mRNA. Cell 2006; 127:1389-400.
    • (2006) Cell , vol.127 , pp. 1389-1400
    • Cheng, H.1    Dufu, K.2    Lee, C.S.3    Hsu, J.L.4    Dias, A.5    Reed, R.6
  • 16
    • 22344438756 scopus 로고    scopus 로고
    • Recruitment of the human TREX complex to mRNA during splicing
    • Masuda S, Das R, Cheng H, Hurt E, Dorman N, Reed R. Recruitment of the human TREX complex to mRNA during splicing. Genes Dev 2005; 19:1512-7.
    • (2005) Genes Dev , vol.19 , pp. 1512-1517
    • Masuda, S.1    Das, R.2    Cheng, H.3    Hurt, E.4    Dorman, N.5    Reed, R.6
  • 17
    • 0141469976 scopus 로고    scopus 로고
    • Yra1p, a conserved nuclear RNAbinding protein, interacts directly with Mex67p and is required for mRNA export
    • Strasser K, Hurt E. Yra1p, a conserved nuclear RNAbinding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J 2000; 19:410-20.
    • (2000) EMBO J , vol.19 , pp. 410-420
    • Strasser, K.1    Hurt, E.2
  • 18
    • 0037175374 scopus 로고    scopus 로고
    • REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export
    • Gatfield D, Izaurralde E. REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol 2002; 159:579-88.
    • (2002) J Cell Biol , vol.159 , pp. 579-588
    • Gatfield, D.1    Izaurralde, E.2
  • 19
    • 0344338368 scopus 로고
    • Gene gating: A hypothesis
    • Blobel G. Gene gating: a hypothesis. Proc Natl Acad Sci USA 1985; 82:8527-9.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8527-8529
    • Blobel, G.1
  • 20
    • 62549141017 scopus 로고    scopus 로고
    • Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export
    • Jani D, Lutz S, Marshall NJ, Fischer T, Kohler A, Ellisdon AM, et al. Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol Cell 2009; 33:727-37.
    • (2009) Mol Cell , vol.33 , pp. 727-737
    • Jani, D.1    Lutz, S.2    Marshall, N.J.3    Fischer, T.4    Kohler, A.5    Ellisdon, A.M.6
  • 21
    • 18744370194 scopus 로고    scopus 로고
    • The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores
    • Fischer T, Strasser K, Racz A, Rodriguez-Navarro S, Oppizzi M, Ihrig P, et al. The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J 2002; 21:5843-52.
    • (2002) EMBO J , vol.21 , pp. 5843-5852
    • Fischer, T.1    Strasser, K.2    Racz, A.3    Rodriguez-Navarro, S.4    Oppizzi, M.5    Ihrig, P.6
  • 22
    • 33745001795 scopus 로고    scopus 로고
    • SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
    • Cabal GG, Genovesio A, Rodriguez-Navarro S, Zimmer C, Gadal O, Lesne A, et al. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature 2006; 441:770-3.
    • (2006) Nature , vol.441 , pp. 770-773
    • Cabal, G.G.1    Genovesio, A.2    Rodriguez-Navarro, S.3    Zimmer, C.4    Gadal, O.5    Lesne, A.6
  • 23
    • 40349113413 scopus 로고    scopus 로고
    • Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes
    • Brown CR, Kennedy CJ, Delmar VA, Forbes DJ, Silver PA. Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes Dev 2008; 22:627-39.
    • (2008) Genes Dev , vol.22 , pp. 627-639
    • Brown, C.R.1    Kennedy, C.J.2    Delmar, V.A.3    Forbes, D.J.4    Silver, P.A.5
  • 24
    • 34249307315 scopus 로고    scopus 로고
    • Nuclear organization of the genome and the potential for gene regulation
    • Fraser P, Bickmore W. Nuclear organization of the genome and the potential for gene regulation. Nature 2007; 447:413-7.
    • (2007) Nature , vol.447 , pp. 413-417
    • Fraser, P.1    Bickmore, W.2
  • 27
    • 12944266918 scopus 로고    scopus 로고
    • A novel nuclear phosphoprotein, GANP, is upregulated in centrocytes of the germinal centre and associated with MCM3, a protein essential for DNA replication
    • Kuwahara K, Yoshida M, Kondo E, Sakata A, Watanabe Y, Abe E, et al. A novel nuclear phosphoprotein, GANP, is upregulated in centrocytes of the germinal centre and associated with MCM3, a protein essential for DNA replication. Blood 2000; 95:2321-8.
    • (2000) Blood , vol.95 , pp. 2321-2328
    • Kuwahara, K.1    Yoshida, M.2    Kondo, E.3    Sakata, A.4    Watanabe, Y.5    Abe, E.6
  • 28
    • 21344446332 scopus 로고    scopus 로고
    • Increased expression of germinal center-associated nuclear protein RNA-primase is associated with lymphomagenesis
    • Fujimura S, Xing Y, Takeya M, Yamashita Y, Ohshima K, Kuwahara K, et al. Increased expression of germinal center-associated nuclear protein RNA-primase is associated with lymphomagenesis. Cancer Res 2005; 65:5925-34.
    • (2005) Cancer Res , vol.65 , pp. 5925-5934
    • Fujimura, S.1    Xing, Y.2    Takeya, M.3    Yamashita, Y.4    Ohshima, K.5    Kuwahara, K.6
  • 29
    • 0742270965 scopus 로고    scopus 로고
    • Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses
    • Kuwahara K, Fujimura S, Takahashi Y, Nakagata N, Takemori T, Aizawa S, et al. Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses. PNAS 2004; 101:1010-5.
    • (2004) PNAS , vol.101 , pp. 1010-1015
    • Kuwahara, K.1    Fujimura, S.2    Takahashi, Y.3    Nakagata, N.4    Takemori, T.5    Aizawa, S.6
  • 30
    • 34848924366 scopus 로고    scopus 로고
    • GANP suppresses DNA recombination, measured by direct-repeat betagalactosidase gene construct, but does not suppress the type of recombination applying to immunoglobulin genes in mammalian cells
    • Yoshida M, Kuwahara K, Shimasaki T, Nakagata N, Matsuoka M, Sakaguchi N. GANP suppresses DNA recombination, measured by direct-repeat betagalactosidase gene construct, but does not suppress the type of recombination applying to immunoglobulin genes in mammalian cells. Genes Cells 2007; 12:1205-13.
    • (2007) Genes Cells , vol.12 , pp. 1205-1213
    • Yoshida, M.1    Kuwahara, K.2    Shimasaki, T.3    Nakagata, N.4    Matsuoka, M.5    Sakaguchi, N.6
  • 31
    • 0032575659 scopus 로고    scopus 로고
    • Identification of a Novel MCM3-associated Protein that Facilitates MCM3 Nuclear Localisation
    • Takei Y, Tsujimoto G. Identification of a Novel MCM3-associated Protein that Facilitates MCM3 Nuclear Localisation. J Biol Chem 1998; 273:22177-80.
    • (1998) J Biol Chem , vol.273 , pp. 22177-22180
    • Takei, Y.1    Tsujimoto, G.2
  • 32
    • 0037044723 scopus 로고    scopus 로고
    • The MCM3 Acetylase MCM3AP Inhibits Initiation, but Not Elongation, of DNA Replication via Interaction with MCM3
    • Takei Y, Assenberg M, Tsujimoto G, Laskey R. The MCM3 Acetylase MCM3AP Inhibits Initiation, but Not Elongation, of DNA Replication via Interaction with MCM3. J Biol Chem 2002; 277:43121-5.
    • (2002) J Biol Chem , vol.277 , pp. 43121-43125
    • Takei, Y.1    Assenberg, M.2    Tsujimoto, G.3    Laskey, R.4
  • 33
    • 0034687059 scopus 로고    scopus 로고
    • Structure, expression and chromosomal localisation of the human gene encoding a germinal centre-associated nuclear protein (GANP) that associates with MCM3 involved in the initiation of DNA replication
    • Abe E, Kuwahara K, Yoshida M, Suzuki M, Terasaki H, Matsuo Y, et al. Structure, expression and chromosomal localisation of the human gene encoding a germinal centre-associated nuclear protein (GANP) that associates with MCM3 involved in the initiation of DNA replication. Gene 2000; 255:219-27.
    • (2000) Gene , vol.255 , pp. 219-227
    • Abe, E.1    Kuwahara, K.2    Yoshida, M.3    Suzuki, M.4    Terasaki, H.5    Matsuo, Y.6
  • 36
    • 40749091704 scopus 로고    scopus 로고
    • Centrin 2 localizes to the vertebrate nuclear pore and plays a role in mRNA and protein export
    • Resendes KK, Rasala BA, Forbes DJ. Centrin 2 localizes to the vertebrate nuclear pore and plays a role in mRNA and protein export. Mol Cell Biol 2008; 28:1755-69.
    • (2008) Mol Cell Biol , vol.28 , pp. 1755-1769
    • Resendes, K.K.1    Rasala, B.A.2    Forbes, D.J.3
  • 37
    • 0034851781 scopus 로고    scopus 로고
    • Nuclear domains
    • Spector DL. Nuclear domains. J Cell Sci 2001; 114:2891-3.
    • (2001) J Cell Sci , vol.114 , pp. 2891-2893
    • Spector, D.L.1
  • 38
    • 17044441683 scopus 로고    scopus 로고
    • The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
    • Bachi A, Braun IC, Rodrigues JP, Pante N, Ribbeck K, von Kobbe C, et al. The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA 2000; 6:136-58.
    • (2000) RNA , vol.6 , pp. 136-158
    • Bachi, A.1    Braun, I.C.2    Rodrigues, J.P.3    Pante, N.4    Ribbeck, K.5    von Kobbe, C.6
  • 39
    • 0034800318 scopus 로고    scopus 로고
    • Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor
    • Fribourg S, Braun IC, Izaurralde E, Conti E. Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor. Mol Cell 2001; 8:645-56.
    • (2001) Mol Cell , vol.8 , pp. 645-656
    • Fribourg, S.1    Braun, I.C.2    Izaurralde, E.3    Conti, E.4
  • 40
    • 17644443879 scopus 로고    scopus 로고
    • In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei
    • Custodio N, Carvalho C, Condado I, Antoniou M, Blencowe BJ, Carmo-Fonseca M. In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei. Rna 2004; 10:622-33.
    • (2004) Rna , vol.10 , pp. 622-633
    • Custodio, N.1    Carvalho, C.2    Condado, I.3    Antoniou, M.4    Blencowe, B.J.5    Carmo-Fonseca, M.6
  • 41
    • 34547879583 scopus 로고    scopus 로고
    • The SAGA continues: Expanding the cellular role of a transcriptional co-activator complex
    • Baker SP, Grant PA. The SAGA continues: expanding the cellular role of a transcriptional co-activator complex. Oncogene 2007; 26:5329-40.
    • (2007) Oncogene , vol.26 , pp. 5329-5340
    • Baker, S.P.1    Grant, P.A.2
  • 43
    • 10744233477 scopus 로고    scopus 로고
    • Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery
    • Rodriguez-Navarro S, Fischer T, Luo MJ, Antunez O, Brettschneider S, Lechner J, et al. Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery. Cell 2004; 116:75-86.
    • (2004) Cell , vol.116 , pp. 75-86
    • Rodriguez-Navarro, S.1    Fischer, T.2    Luo, M.J.3    Antunez, O.4    Brettschneider, S.5    Lechner, J.6
  • 44
    • 75749103380 scopus 로고    scopus 로고
    • Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes
    • Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer MW. Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. Cell; 140:372-83.
    • Cell , vol.140 , pp. 372-383
    • Capelson, M.1    Liang, Y.2    Schulte, R.3    Mair, W.4    Wagner, U.5    Hetzer, M.W.6
  • 45
    • 75749117571 scopus 로고    scopus 로고
    • Nucleoporins directly stimulate expression of developmental and cell cycle genes inside the nucleoplasm
    • Kalverda B, Pickersgill H, Shloma VV, Fornerod M. Nucleoporins directly stimulate expression of developmental and cell cycle genes inside the nucleoplasm. Cell; 140:360-71.
    • Cell , vol.140 , pp. 360-371
    • Kalverda, B.1    Pickersgill, H.2    Shloma, V.V.3    Fornerod, M.4
  • 47
    • 17944366840 scopus 로고    scopus 로고
    • Germinal centre-associated nuclear protein (GANP) has a phosphorylationdependent DNA-primase activity that is upregulated in germinal centre regions
    • Kuwahara K, Tomiyasu S, Fujimura S, Nomura K, Xing Y, Nishiyama N, et al. Germinal centre-associated nuclear protein (GANP) has a phosphorylationdependent DNA-primase activity that is upregulated in germinal centre regions. Proc Natl Acad Sci USA 2001; 98:10279-83.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10279-10283
    • Kuwahara, K.1    Tomiyasu, S.2    Fujimura, S.3    Nomura, K.4    Xing, Y.5    Nishiyama, N.6


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