Benzophenone-3 entrapped in solid lipid microspheres: Formulation and in vitro skin evaluation

International Journal of Pharmaceutics

Volumn 400, Issue 1-2, 2010, Pages 1-7

  Mestres, J P ^b   Duracher, L ^a   Baux, C ^a   Vian, L ^a   Marti Mestres, G ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

Benzophenone 3; Microparticles; Percutaneous penetration; Solid lipid microspheres; Targeted drug delivery

Indexed keywords

DRUG CARRIER; DRUG VEHICLE; MICROSPHERE; NONIONIC SURFACTANT; OXYBENZONE; SOLID LIPID NANOPARTICLE;

ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; IN VITRO STUDY; LIPOPHILICITY; NONHUMAN; PARTICLE SIZE; POLARIZATION MICROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SKIN PENETRATION; ULTRAVIOLET RADIATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; BENZOPHENONES; DRUG CARRIERS; DRUG STABILITY; EAR, EXTERNAL; LIPIDS; MICROSPHERES; PARTICLE SIZE; PERMEABILITY; SKIN; SKIN ABSORPTION; SUNSCREENING AGENTS; SWINE;

EID: 77957663309     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.07.028     Document Type: Article

References (21)

1. Albertini B., Mezzena M., Passerini N., Rodriguez L., Scalia S. Evaluation of spray congealing as technique for the preparation of highly loaded solid lipid microparticles containing the sunscreen agent, avobenzone. J. Pharm. Sci. 2009, 98:2759-2769.
2. Al haushey L., Bolzinger M.A., Bordes C., Gauvrit J.Y., Briançon S. Improvement of a bovine serum albumin microencapsulation process by screening design. Int. J. Pharm. 2007, 344:16-25.
3. Fernandez C., Marti-Mestres G., Mestres J.P., Maillols H. LC analysis of benzophenone-3 in pigskin and in saline solution. II. Application to determination of 'in vitro' and 'in vivo' skin penetration from solvents, coarse and submicron emulsions. J. Pharm. Biomed. Anal. 2000, 24:155-165.
4. Fernandez C., Marti-Mestres G., Mestres J.P., Maillols H. LC analysis of benzophenone-3 in pigskin and in saline solution. Application to determination of in vitro skin penetration. J. Pharm. Biomed. 2000, 22:393-402.
5. Iannuccelli V., Sala N., Tursilli R., Coppi G., Scalia S. Influence of liposphere preparation on butylmethoxydibenzoylmethane photostability. Eur. J. Pharm. Biopharm. 2006, 63:140-145.
6. Küchler S., Radowski M.R., Blaschke T., Dathe M., Plendl J., Haag R., Schäfer-Korting M., Kramer K.D. Nanoparticles for skin penetration enhancement - a comparison of a dendritic core-multishell-nanotransporter and solid lipid nanoparticles. Eur. J. Pharm. Biopharm. 2009, 71:243-250.
7. Larroque M., Mestres J.P., Garreau H., Marti-Mestres G. Lipid microspheres in sunscreen formulations. Skin and Formulation 2003, 16.
8. Lombardi Borgia S., Regehly M., Sivaramakrishnan R., Mehnert W., Korting H.C., Danker K., Röder B., Kramer K.D., Schäfer-Korting M. Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. J. Control. Release 2005, 110:151-163.
9. Marti-Mestres G., Mestres J.P., Bres J., Martin S., Ramos J., Vian L. The " in vitro" percutaneous penetration of three antioxidant compounds. Int. J. Pharm. 2007, 331:139-144.
10. Pardeike J., Hommoss A., Müller R.H. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int. J. Pharm. 2009, 366:170-184.
11. Puglia C., Blasi P., Rizza L., Schoubben A., Bonina F., Rossi C., Ricci M. Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation. Int. J. Pharm. 2008, 357:295-304.
12. Schäfer-Korting M., Mehnert W., Korting H.C. Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv. Drug Deliv. Rev. 2007, 59:427-443.
13. SCCP, 2006a. Opinion on benzophenone-3. Colipa n° S38 adopted by the Scientific Committee on Consumer Products during the 10th Plenary. European Commission, SCCP/1069/06. http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_078.pdf.
14. SCCP, 2006b. Opinion for Basic criteria for the in vitro assessment of dermal absorption of cosmetic ingredients. adopted by the Scientific Committee on Consumer Products during the 7th Plenary. European Commission, SCCP/0970/06. http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_s_03.pdf.
15. Statgraphics Plus, 2001. Manugistics, Inc., Maryland, USA.
16. Stecova J., Mehnert W., Blaschke T., Kleuser B., Sivaramakrishnan R., Zouboulis C.C., Seltmann H., Korting H.C., Kramer K.D., Schäfer-Korting M. Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptake. Pharm. Res. 2007, 24:991-1000.
17. Trotta M., Debernardi F., Caputto O. Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique. Int. J. Pharm. 2003, 257:153-160.
18. Tursilli R., Piel G., Delattre L., Scalia S. Solid lipid microparticles containing the sunscreen agent, octyl-dimethylaminobenzoate: effect of the vehicle. Eur. J. Pharm. Biopharm. 2007, 66:483-487.
19. Wissing S.A., Mäder K., Müller R.H. Prolonged efficacy of the insect repellent lemon oil by incorporation into solid lipid nanoparticles (SLNTM). Proceeding in the 3rd World Meeting of Pharmacy, Biopharmacy and Pharmaceutical Technology 2000.
20. Wissing S.A., Mäder K., Müller R.H. Solid lipid nanoparticles (SLN) as a novel carrier system offereing prolonged release of perfume Allure (Chanel). Int. Symp. Control. Release Bioact. Mater., vol. 27 2000, 311-312.
21. Yener G., Incegül T., Yener T.N. Importance of using solid lipid microspheres as carriers for UV filters on the example octyl methoxy cinnamate. Int. J. Pharm. 2003, 258:203-207.