Development and validation of a pediatric severity index for sickle cell patients

American Journal of Hematology

Volumn 85, Issue 10, 2010, Pages 746-751

  Van Den Tweel, Xandra W ^a   Van Der Lee, Johanna H ^a   Heijboer, Harriët ^a   Peters, Marjolein ^a   Fijnvandraat, Karin ^a  

^a EMMA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHILD; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; GENE DELETION; GENOTYPE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT CODING; PEDIATRIC SEVERITY INDEX; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SCORING SYSTEM; SICKLE CELL ANEMIA; VALIDATION STUDY; VALIDITY; AGE; BETA THALASSEMIA; BLOOD; CLASSIFICATION; COMPLICATION; GENETICS; INCIDENCE; LENGTH OF STAY; MORTALITY; OSTEONECROSIS; PAIN; PNEUMOCOCCAL INFECTIONS; RISK; SEVERITY OF ILLNESS INDEX; SICKLE CELL TRAIT; STATISTICS AND NUMERICAL DATA; THROMBOSIS;

BIOLOGICAL MARKER;

ADOLESCENT; AGE FACTORS; ANEMIA, SICKLE CELL; BETA-THALASSEMIA; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; GENOTYPE; HOSPITALIZATION; HUMANS; INCIDENCE; LENGTH OF STAY; OSTEONECROSIS; PAIN; PNEUMOCOCCAL INFECTIONS; RISK; SEVERITY OF ILLNESS INDEX; SICKLE CELL TRAIT; THROMBOSIS;

EID: 77957663223     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21846     Document Type: Article

References (16)

1. Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 1994;330:1639-1644.
2. Steinberg MH, Dreiling BJ, Morrison FS, et al. Mild sickle cell disease. Clinical and laboratory studies. JAMA 1973;224:317-321.
3. Serjeant GR, Higgs DR, Hambleton IR. Elderly survivors with homozygous sickle cell disease. N Engl J Med 2007;356:642-643.
4. Miller ST, Sleeper LA, Pegelow CH, et al. Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med 2000;342:83-89.
5. Steinberg MH, Rodgers GP. Pathophysiology of sickle cell disease: Role of cellular and genetic modifiers. Semin Hematol 2001;38:299-306.
6. Sebastiani P, Ramoni MF, Nolan V, et al. Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet 2005;37:435-440.
7. Cameron BF, Christian E, Lobel JS, et al. Evaluation of clinical severity in sickle cell disease. J Natl Med Assoc 1983;75:483-487.
8. Day SW. Development and evaluation of a sickle cell assessment instrument. Pediatr Nurs 2004;30:451-458.
9. Pearson SR, Alkon A, Treadwell M, et al. Autonomic reactivity and clinical severity in children with sickle cell disease. Clin Auton Res 2005;15:400-407.
10. Nolan VG, Wyszynski DF, Farrer LA, et al. Hemolysis-associated priapism in sickle cell disease. Blood 2005;106:3264-3267.
11. Vichinsky EP, Neumayr LD, Earles AN, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med 2000;342:1855-1865.
12. Powars D, Weidman JA, Odom-Maryon T, et al. Sickle cell chronic lung disease: Prior morbidity and the risk of pulmonary failure. Medicine (Baltimore) 1988;67:66-76.
13. Castro O, Brambilla DJ, Thorington B, et al. The acute chest syndrome in sickle cell disease: Incidence and risk factors. The Cooperative Study of Sickle Cell Disease. Blood 1994;84:643-649.
14. Sebastiani P, Nolan VG, Baldwin CT, et al. A network model to predict the risk of death in sickle cell disease. Blood 2007;110:2727-2735.
15. Terwee CB, Bot SD, de Boer MR, et al. Quality criteria were proposed for measurement properties of health status questionnaires. J Clin Epidemiol 2007;60:34-42.
16. Altman DG. Practical Statistics for Medical Research. London. Chapman & Hall: Chapman & Hall; 1991.