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Volumn 6, Issue 10, 2010, Pages 558-559

Therapy: Immunogenicity of biologic therapies-we need tolerance

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; AZATHIOPRINE; EPITOPE; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; METHOTREXATE; TUMOR NECROSIS FACTOR INHIBITOR;

EID: 77957594345     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2010.153     Document Type: Short Survey
Times cited : (9)

References (10)
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    • Dealing with immunogenicity of biologicals: Assessment and clinical relevance
    • Wolbink, G. J., Aarden, L. A. & Dijkmans, B. A. Dealing with immunogenicity of biologicals: assessment and clinical relevance. Curr. Opin. Rheumatol. 21, 211-215 (2009).
    • (2009) Curr. Opin. Rheumatol. , vol.21 , pp. 211-215
    • Wolbink, G.J.1    Aarden, L.A.2    Dijkmans, B.A.3
  • 3
    • 34347267600 scopus 로고    scopus 로고
    • Clinical response to adalimumab: Relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis
    • Bartelds, G. M. et al. Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis. Ann. Rheum. Dis. 66, 921-926 (2007).
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 921-926
    • Bartelds, G.M.1
  • 4
    • 77956209762 scopus 로고    scopus 로고
    • A novel strategy to reduce the immunogenicity of biological therapies
    • Somerfield, J. et al. A novel strategy to reduce the immunogenicity of biological therapies. J. Immunol. 185, 763-768 (2010)
    • (2010) J. Immunol. , vol.185 , pp. 763-768
    • Somerfield, J.1
  • 5
    • 0028862268 scopus 로고
    • CAMPATH-1H, a humanized monoclonal antibody, in refractory rheumatoid arthritis. An intravenous dose-escalation study
    • Weinblatt, M. E. et al. CAMPATH-1H, a humanized monoclonal antibody, in refractory rheumatoid arthritis. An intravenous dose-escalation study. Arthritis Rheum. 38, 1589-1594 (1995).
    • (1995) Arthritis Rheum. , vol.38 , pp. 1589-1594
    • Weinblatt, M.E.1
  • 6
    • 54949143968 scopus 로고    scopus 로고
    • Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
    • Coles, A. J. et al. Alemtuzumab vs. interferon beta-1a in early multiple sclerosis. N. Engl. J. Med. 359, 1786-1801 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 1786-1801
    • Coles, A.J.1
  • 7
    • 0033559501 scopus 로고    scopus 로고
    • Elimination of the mmunogenicity of therapeutic antibodies
    • Gilliland, L. K. et al. elimination of the mmunogenicity of therapeutic antibodies. J. Immunol. 162, 3663-3671 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 3663-3671
    • Gilliland, L.K.1
  • 8
    • 0031660364 scopus 로고    scopus 로고
    • Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
    • Maini, R. N. et al. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum. 41, 1552-1563 (1998).
    • (1998) Arthritis Rheum. , vol.41 , pp. 1552-1563
    • Maini, R.N.1
  • 9
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn's disease
    • Colombel, J. F. et al. infliximab, azathioprine, or combination therapy for Crohn's disease. N. Engl. J. Med. 362, 1383-1395 (2010).
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1383-1395
    • Colombel, J.F.1
  • 10
    • 77950673538 scopus 로고    scopus 로고
    • Optimization algorithms for functional deimmunization of therapeutic proteins
    • Parker, A. S., Zheng, W., Griswold, K. E. & Bailey-Kellogg, C. Optimization algorithms for functional deimmunization of therapeutic proteins. BMC Bioinformatics 11, 180 (2010).
    • (2010) BMC Bioinformatics , vol.11 , Issue.180
    • Parker, A.S.1    Zheng, W.2    Griswold, K.E.3    Bailey-Kellogg, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.