Umbilical cord-derived mesenchymal stem cells isolated by a novel explantation technique can differentiate into functional endothelial cells and promote revascularization

Stem Cells and Development

Volumn 19, Issue 10, 2010, Pages 1511-1522

  Xu, Yan ^a   Meng, Hengxing ^b   Li, Changhong ^a   Hao, Mu ^a   Wang, Yafei ^a   Yu, Zhen ^a   Li, Qian ^a,b   Han, Junling ^a,b   Zhai, Qiongli ^c   Qiu, Lugui ^a,b  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b National Research Center for Stem Cell Engineering and Technology   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY DENSITY; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL ISOLATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSPLANTATION; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPLANT; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO CULTURE; ISCHEMIA; LIMB ISCHEMIA; LIMB PERFUSION; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVASCULARIZATION; STEM CELL; UMBILICAL CORD;

ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SEPARATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; HINDLIMB; HUMANS; ISCHEMIA; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOCYTES; UMBILICAL CORD;

MUS;

EID: 77957579877     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2009.0321     Document Type: Article

References (27)

1. Levenberg S, J Rouwkema, M Macdonald, ES Garfein, DS Kohane, DC Darland, R Marini, CA van Blitterswijk, RC Mulligan, PAD Amore and R Langer. (2005). Engineering vascularized skeletal muscle tissue. Nat Biotechnol 23:879-884.
2. Herzog EL, L Chai and DS Krause. (2003). Plasticity of marrow-derived stem cells. Blood 102:3483-3493.
3. Oswald J, S Boxberger, B Jørgensen, S Feldmann, G Ehninger, M Bornhäuser and C Werner. (2004). Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22:377-384. (Pubitemid 38736621)
4. Lakshmipathy, U and C Verfaillie. (2005). Stem cell plasticity. Blood Rev 19:29-38. (Pubitemid 39574247)
5. Deans RJ and AB Moseley. (2000). Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 28:875-884.
6. Romanov YA, VA Svintsitskaya and VN Smirnov. (2003). Searching for alternative sources of postnatal human mesenchymal stem cells: candidate MSC-like cells from umbilical cord. Stem Cells 21:105-110.
7. Nekanti U, VB Rao, AG Bahirvani, M Jan, S Totey and M Ta. (2010). Long-term expansion and pluripotent marker array analysis of Wharton's jelly-derived mesenchymal stem cells. Stem Cells Dev 19:117-130.
8. Sarugaser R, D Lickorish, D Baksh, MM Hosseini and JE Davies. (2005). Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 23:220-229.
9. Kestendjieva S, D Kyurkchiev, G Tsvetkova, T Mehandjiev, A Dimitrov, A Nikolov and S Kyurkchiev. (2008). Characterization of mesenchymal stem cells isolated from the human umbilical cord. Cell Biol Int 32:724-732.
10. Zucconi E, NM Vieira, DF Bueno, M Secco, T Jazedje, CE Ambrosio, MR Passos-Bueno, MA Miglino and Zatz M. (2010). Mesenchymal stem cells derived from canine umbilical cord vein: a novel source for cell therapy studies. Stem Cells Dev Feb 17. [Epub ahead of print]
11. Weiss ML, S Medicetty, AR Bledsoe, RS Rachakatla, M Choi, S Merchav, Y Luo, MS Rao, G Velagaleti and D Troyer. (2006). Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells 24:781-792.
12. Fu YS, YC Cheng, MY Lin, H Cheng, PM Chu, SC Chou, YH Shih, MH Ko and MS Sung. (2006). Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism. Stem Cells 24:115-124.
13. Aranguren XL, JD McCue, B Hendrickx, XH Zhu, F Du, E Chen, B Pelacho, I Peñuelas, G Abizanda, M Uriz, SA Frommer, JJ Ross, BA Schroeder, MS Seaborn, JR Adney, J Hagenbrock, NH Harris, Y Zhang, X Zhang, MH Nelson-Holte, Y Jiang, AD Billiau, W Chen, F Prosper, CM Verfaillie and A Luttun. (2008). Multipotent adult progenitor cells sustain function of ischemic limbs in mice. J Clin Invest 118:505-514.
14. Liu JW, S Dunoyer-Geindre, V Serre-Beinier, G Mai, JF Lambert, RJ Fish, G Pernod, L Buehler, H Bounameaux and EK Kruithof. (2007). Characterization of endothelial-like cells derived from human mesenchymal stem cells. J Thromb Haemost 5:826-834.
15. Zhuang H, JP Zheng, H Gao and K De Yao. (2007). In vitro biodegradation and biocompatibility of gelatin/montmorillonitechitosan intercalated nanocomposite. J Mater Sci Mater Med 18:951-957
16. Hristov M and C Weber. (2004). Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance. J Cell Mol Med 8:498-508.
17. Goodwin HS, AR Bicknese, SN Chien, BD Bogucki, CO Quinn and DA Wall. (2001). Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers. Biol Blood Marrow Transplant 7:581-588.
18. Reyes M, A Dudek, B Jahagirdar, L Koodie, PH Marker and CM Verfaillie. (2002). Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 109:337-346.
19. Rao MS and MP Mattson. (2001). Stem cells and aging: expanding the possibilities. Mech Ageing Dev 122:713-734.
20. Wexler SA, C Donaldson, P Denning-Kendall, C Rice, B Bradley and JM Hows. (2003). Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not. Br J Haematol 121:368-374.
21. Yu M, Z Xiao, L Shen and L Li. (2004). Mid-trimester fetal blood-derived adherent cells share characteristics similar to mesenchymal stem cells but full-term umbilical cord blood does not. Br J Haematol 124:666-675.
22. Ferrara N. (2004). Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25:581-611. (Pubitemid 39099316)
23. Kern S, H Eichler, J Stoeve, H Klüter and K Bieback. (2006). Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24:1294-1301.
24. Yue WM, W Liu, YW Bi, XP He., WY Sun, XY Pang, XH Gu and XP Wang. (2008). Mesenchymal stem cells differentiate into an endothelial phenotype, reduce neointimal formation, and enhance endothelial function in a rat vein grafting model. Stem Cells Dev 17:785-793.
25. Silva GV, S Litovsky, JA Assad, AL Sousa, BJ Martin, D Vela, SC Coulter, J Lin, J Ober, WK Vaughn, RV Branco, EM Oliveira, R He, YJ Geng, JT Willerson and EC Perin. (2005). Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 111:150-156.
26. Kinnaird T, E Stabile, MS Burnett, M Shou, CW Lee, S Barr, S Fuchs and SE Epstein. (2004). Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 109:1543-1549.
27. Nakagami H, K Maeda, R Morishita, S Iguchi, T Nishikawa, Y Takami, Y Kikuchi, Y Saito, K Tamai, T Ogihara and Y Kaneda. (2005). Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vase Biol 25: 2542-2547