A concise, total synthesis and antibacterial evaluation of 2-hydroxy-1-(1H-indol-3-yl)-4-methylpentan-3-one

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 19, 2010, Pages 5739-5742

  Nguyen, Son T ^a   Butler, Michelle M ^a   Varady, Laszlo ^b   Peet, Norton P ^a   Bowlin, Terry L ^a  

^a MICROBIOTIX INC   (United States)

^b Rilas Technologies Inc   (United States)

Author keywords

Acyloin natural products; Antibiotic; Nematode; Xenorhabdus

Indexed keywords

2 HYDROXY 1 (1H INDOL 3 YL) 4 METHYLPENTAN 3 ONE; 2 HYDROXY 3 (1H INDOL 3YL)PROPIONIC ACID METHYL ESTER; 3 HYDROXY 1 (INDOL 3 YL) 4 METHYLPENTAN 2 ONE; ACETIC ACID DERIVATIVE; ANTIINFECTIVE AGENT; ISOPROPYL MAGNESIUM CHLORIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; DRUG SYNTHESIS; ENANTIOMER; ESCHERICHIA COLI; ISOMER; NONHUMAN; STAPHYLOCOCCUS AUREUS; SUPERCRITICAL FLUID CHROMATOGRAPHY;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; ESCHERICHIA COLI; INDOLES; ISOMERISM; MICROBIAL SENSITIVITY TESTS; PROPIONIC ACIDS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; STAPHYLOCOCCUS AUREUS; XENORHABDUS;

EID: 77957567677     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.08.003     Document Type: Article

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