Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: Clinical and pharmacologic factors affecting outcome

Journal of Clinical Oncology

Volumn 28, Issue 25, 2010, Pages 3979-3986

  Widemann, Brigitte C ^a   Balis, Frank M ^a   Kim, AeRang ^a   Boron, Matthew ^a   Jayaprakash, Nalini ^a   Shalabi, Aiman ^a   O'Brien, Michelle ^a   Eby, Michelle ^a   Cole, Diane E ^a   Murphy, Robert F ^a   Fox, Elizabeth ^a   Ivy, Percy ^a   Adamson, Peter C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CARBOXYPEPTIDASE G2; FOLINIC ACID; METHOTREXATE; THYMIDINE; GAMMA GLUTAMYL HYDROLASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; BONE MARROW SUPPRESSION; BRAIN DISEASE; BURNING SENSATION; CHILD; COHORT ANALYSIS; CONFUSION; CONTINUOUS INFUSION; DEATH; DIZZINESS; DRUG FATALITY; EARLY INTERVENTION; EPIDERMOLYSIS; ERYTHEMA; FEBRILE NEUTROPENIA; FEELING OF WARMTH; FEMALE; FLUSHING; HEAD PRESSURE; HUMAN; INFANT; KIDNEY FAILURE; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; NAUSEA; NEPHROTOXICITY; NEUROTOXICITY; NEUTROPENIA; NONHODGKIN LYMPHOMA; OSTEOSARCOMA; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEPSIS; SHAKING; SIDE EFFECT; SINGLE DRUG DOSE; SOMNOLENCE; THROMBOCYTOPENIA; TINGLING FINGER; TREATMENT OUTCOME; TREMOR; VOMITING; BLOOD; CHEMICALLY INDUCED DISORDER; DRUG ADMINISTRATION; DRUG COMBINATION; KIDNEY DISEASE; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; GAMMA-GLUTAMYL HYDROLASE; HUMANS; INFANT; KIDNEY DISEASES; LEUCOVORIN; MALE; METHOTREXATE; MIDDLE AGED; THYMIDINE;

EID: 77957566458     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2009.25.4540     Document Type: Article

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